Age-related changes in spontaneous behavior and learning in NMRI mice from maturity to middle age

1990 ◽  
Vol 47 (6) ◽  
pp. 1137-1144 ◽  
Author(s):  
Yves Lamberty ◽  
Alma J. Gower
Keyword(s):  
Middle Age ◽  
Nmri Mice ◽  
Age Related ◽  
Spontaneous Behavior ◽  
Age Related Changes

scholarly journals Age-related changes in spatial navigation are evident by midlife and differ by sex

2020 ◽  
Author(s):  
Shuying Yu ◽  
Alexander Paul Boone ◽  
Carol He ◽  
Rie Davis ◽  
Mary Hegarty ◽  
...  
Keyword(s):  
Path Integration ◽  
Middle Age ◽  
Spatial Navigation ◽  
Spatial Knowledge ◽  
Early Age ◽  
Age Related ◽  
Navigation Path ◽  
Spatial Knowledge Acquisition ◽  
Age Related Changes ◽  
Navigation Strategies

Accumulating evidence suggests that distinct aspects of successful navigation—path integration, acquiring spatial knowledge, and navigation strategies—change with advanced age. Yet, few studies have established whether navigation deficits emerge early in the aging process (prior to age 65) or whether early age-related deficits vary by sex. Here, we probed healthy young (ages 18-28) and midlife (ages 43-61) adults on three essential aspects of navigation. First, path integration ability shows negligible effects of sex or age. Second, robust sex differences in spatial knowledge acquisition are observed in young adulthood and persist, but are diminished, with age. Third, by midlife, men and women show decreased ability to acquire spatial knowledge and increased reliance on taking habitual paths. Together, our findings indicate that age-related changes in navigation ability and strategy are evident as early as midlife and that path integration ability is relatively spared in the transition from youth to middle age.

scholarly journals A Report of Two Cases of Age-Related Changes in Cervical Morphology in Postmenopausal Women with Vaginal Adenosis

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Marguerite B. Vigliani
Keyword(s):  
Middle Age ◽  
Morphological Changes ◽  
Pap Smears ◽  
Squamocolumnar Junction ◽  
Age Related ◽  
Normal Cervix ◽  
Vaginal Canal ◽  
Endocervical Canal ◽  
Over Time ◽  
Age Related Changes

This paper presents two cases of women who had extensive vaginal adenosis from prenatal DES exposure, extending almost halfway down the vaginal canal. Both women were followed for decades with annual exams and Pap smears until after menopause. Clinical examination in both cases initially showed an absent pars vaginalis of the cervix, vaginal adenosis, and shallowness of the fornices. Several decades of annual exams showed these stigmata of DES exposure gradually disappear as the upper vagina progressively contracted. After menopause the upper vagina in both cases transformed into what appeared to be a normal cervix with all adenosis involuted into a normal endocervical canal. A timeline was created to show the morphological changes that were observed over time. This timeline illustrates how severe vaginal stenosis above the level of the squamocolumnar junction developed in middle age and was followed in the postmenopause by fusion of the upper vaginal walls in the midline resulting in the appearance of a normal, but prolapsed, cervix.

scholarly journals Age-related changes in body composition persons of middle age (letter 1)

2020 ◽  
pp. 31-41
Author(s):  
Антонина Владимировна Алексеева ◽  
Анатолий Яковлевич Рыжов ◽  
Данила Игоревич Игнатьев
Keyword(s):  
Body Composition ◽  
Middle Age ◽  
Middle Aged ◽  
Men And Women ◽  
Anthropometric Indicators ◽  
Aged People ◽  
Age Related ◽  
Positive Correlations ◽  
Age Related Changes

Исследованы антропометрические показатели и параметры состава тела у лиц среднего возраста. Установлено, что некоторые калиперометрические показатели испытывают различие у мужчин и женщин. Калиперометрические показатели величины кожных покровов спины, медиальной и латеральной поверхностей бедер характеризуются тесными положительными корреляциями. Anthropometric indicators and parameters of body composition in middle-aged people were studied. It is established that some caliperometric indicators experience a difference in men and women. Caliperometric indicators of the size of the skin of the back, medial and lateral surfaces of the thighs are characterized by close positive correlations.

scholarly journals Stability and change in well-being among middle-aged and older Japanese

2020 ◽  
Vol 45 (1) ◽  
pp. 78-88
Author(s):  
Takeshi Nakagawa ◽  
Yukiko Nishita ◽  
Chikako Tange ◽  
Makiko Tomida ◽  
Kaori Kinoshita ◽  
...  
Keyword(s):  
Life Satisfaction ◽  
Negative Affect ◽  
Positive Affect ◽  
Old Age ◽  
Middle Age ◽  
Late Life ◽  
Well Being ◽  
Middle Aged ◽  
Age Related ◽  
Age Related Changes

Prior evidence suggests that subjective well-being (SWB) remains relatively stable across adulthood. However, longitudinal evidence is sparse except in Western societies such as North America and Western Europe. We examined age-related changes in SWB (life satisfaction, positive affect, and negative affect) among middle-aged and older Japanese. We applied multilevel growth models to 14-year seven-wave longitudinal data of a dynamic cohort study. A total of 3,890 participants aged 40–81 at first assessment were included in the analysis. The longitudinal results demonstrated differential trajectories of SWB. Life satisfaction exhibited an accelerated increase in middle age but decreased and leveled off in old age. Positive affect increased in midlife and declined in late life. Negative affect remained stable in middle age but increased in old age. Demographics, health, and methodological correlates did not fully account for age-related changes in SWB. Of note, increases in negative affect in old age remained evident even after controlling for the correlates. In conclusion, life satisfaction was stable across adulthood, which was not the case with positive and negative affect. We discussed the possible mechanisms in these observed trajectories of SWB, in particular, negative affect in late life.

scholarly journals Correlation Between Pulpal and Carotid Arteries Blood Flow in Two Age Groups

2015 ◽  
Vol 62 (3) ◽  
pp. 130-136
Author(s):  
Bojan Dželetović ◽  
Nikola Aleksić ◽  
Djurica Grga ◽  
Tatjana Savić-Stanković ◽  
Ivana Milanović ◽  
...  
Keyword(s):  
Blood Flow ◽  
Carotid Artery ◽  
Carotid Arteries ◽  
Middle Age ◽  
External Carotid Artery ◽  
External Carotid ◽  
Artery Blood Flow ◽  
Pulp Tissue ◽  
Age Related ◽  
Age Related Changes

Abstract Introduction Vascular network of dental pulp is supplied through common and external carotid artery and terminal dental branches that supply each pulp tissue. Age related changes of pulp tissue influence pulpal vascularization as well. The aim of this study was to compare and correlate pulpal and common and external carotid artery blood flow in young and middle age individuals of general population. Material and Methods Two groups of 10 participants were included in the study, young (20-25 years) and middle age (50-55 years) group. Pulpal blood flow (PBF) measurements on intact right and left upper central incisors were performed using laser Doppler flowmetry (LDF) method. Carotid arteries blood flow was assessed using carotid ultrasonography. Results PBF levels were significantly higher in young (3.11±0.67 and 3.46±1.11, right and left upper central incisors, respectively) compared to middle age (1.93±0.47 and 2.30±0.64, right and left upper central incisors, respectively) participants (independent sample t test; p<0.05). There was no correlation between common and external carotid artery blood flow and upper central incisors PBF in young as well as middle age participants, for right or left side. Conclusion Absence of correlation between carotid arteries blood flow and PBF suggests that reduced PBF in middle age participants was probably not due to reduced blood supply from carotid arteries but it was result of age related changes at the level of pulpal blood vessels.

Sleep Through the Ages: Adults and Older Adults

2021 ◽  
pp. 49-64
Author(s):  
Joseph M. Dzierzewski ◽  
Tarah Raldiris ◽  
Scott Ravyts
Keyword(s):  
Mental Health ◽  
Older Adults ◽  
Sleep Disorders ◽  
Middle Age ◽  
Late Life ◽  
Physical And Mental Health ◽  
Older Adulthood ◽  
Age Related ◽  
Rhythm Disorder ◽  
Age Related Changes

Sleep is essential for optimal physical and mental health, particularly in late-life. Thus, knowledge regarding age-related changes in sleep are of particular importance. This chapter begins by synthesizing existing research regarding the normative changes in sleep architecture, timing, and duration which occur from middle age to late-life. These normative changes are characterized by less N3 sleep, earlier bed and wake times, and shorter overall nocturnal sleep duration. The chapter concludes by providing an overview of common sleep disorders in older adulthood, including circadian rhythm disorder, sleep disordered breathing, and insomnia. These sleep disorders become more prevalent with age and are frequently associated with declines in functioning. Overall, though changes in sleep in late-life are common, they tend to occur gradually, with a significant portion of older adults able to maintain adequate sleep as they age.

Age-related changes of mitogen responsiveness in different lymphoid organs from outbred NMRI mice

Immunobiology ◽  
1981 ◽  
Vol 158 (5) ◽  
pp. 439-449 ◽  
Author(s):  
Franziska Joncourt ◽  
Florence Bettens ◽  
Flemming Kristensen ◽  
Alain L. de Weck
Keyword(s):  
Lymphoid Organs ◽  
Nmri Mice ◽  
Age Related ◽  
Mitogen Responsiveness ◽  
Age Related Changes
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