Degradation of polypropylene under gamma irradiation: protection effect of additives

1995 ◽  
Vol 50 (2) ◽  
pp. 203-210 ◽  
Author(s):  
Yanti S. Soebianto ◽  
Isami Kusuhata ◽  
Yosuke Katsumura ◽  
Kenkichi Ishigure ◽  
Junichi Kubo ◽  
...  
Keyword(s):  
Gamma Irradiation ◽  
Protection Effect ◽  
Effect Of Additives ◽  
Irradiation Protection

scholarly journals Studies of the Irradiation Protection Effect of Fetal Liver in Mice. I. Influence of the Gestational Age of the Donor Tissue

Blood ◽  
1961 ◽  
Vol 18 (2) ◽  
pp. 182-186 ◽  
Author(s):  
PAUL N. TSCHETTER ◽  
JOHN H. GITHENS ◽  
M. GIOVANNELLA MOSCOVICI
Keyword(s):  
Gestational Age ◽  
Fetal Liver ◽  
Second Trimester ◽  
Hematopoietic Tissue ◽  
Third Trimester ◽  
Protection Effect ◽  
Late Mortality ◽  
Donor Tissue ◽  
Level Of Significance ◽  
Irradiation Protection

Abstract 1. The gestational age of donor hematopoietic tissue appeared to have no influence on the 30-day mortality following homologous transplants in irradiated mice. 2. Recipients of second trimester homologous donor tissue had a late (90-day) mortality that was 16 per cent lower than that observed in animals receiving tissue from third trimester and neonatal donors, but statistical analysis showed a low level of significance. 3. Irradiation alone appeared to cause a late mortality in non-injected irradiated animals and in isologously transplanted irradiated animals.

scholarly journals Protective Effect of Spin-Labeled 1-Ethyl-1-nitrosourea against Oxidative Stress in Liver Induced by Antitumor Drugs and Radiation

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
V. Gadjeva ◽  
B. Grigorov ◽  
G. Nikolova ◽  
A. Tolekova ◽  
A. Zheleva ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Gamma Irradiation ◽  
Antitumor Drugs ◽  
Protection Effect ◽  
Tumor Bearing ◽  
Liver Injuries ◽  
Liver Homogenates ◽  
Total Body ◽  
Biomarkers Of Oxidative Stress

This study was carried out to investigate possible protection effect of 1-ethyl-3-[4-(2,2,6,6-tetramethylpiperidine-1-oxyl)]-1-nitrosourea (SLENU), synthesized in our laboratory, against oxidative liver injuries induced in mice treated by antitumor drugs: doxorubicin (DOX), bleomycin (BLM), or gamma irradiation (R). Specifically, alterations in some biomarkers of oxidative stress, such as lipid peroxidation products measured as malondialdehyde (MDA) levels and activities of the antioxidant enzymes, superoxide dismutase (SOD) and catalase (CAT), were studied in liver homogenates isolated from tumor bearing C57 black mice after i.p. treatment with solutions of DOX (60 mg/kg), BLM (60 mg/kg), or after total body gamma-irradiation with a single dose of 5 Gy. The same biomarkers were also measured after i.p. pretreatment of mice with SLENU (100 mg/kg). Statistical significant increased MDA levels and SOD and CAT enzymes activities were found in the liver homogenates of tumor bearing mice after alone treatment with DOX or gamma-irradiation compared to the control mice, while these parameters were insignificantly increased after BLM administration compared to the same controls.

scholarly journals Studies of the Irradiation Protection Effect of Fetal Liver in Mice. II. Storage by Freezing

Blood ◽  
1961 ◽  
Vol 18 (3) ◽  
pp. 344-348 ◽  
Author(s):  
JOHN H. GITHENS ◽  
PAUL N. TSCHETTER ◽  
M. GIOVANNELLA MOSCOVICI ◽  
WILLIAM E. HATHAWAY
Keyword(s):  
Radiation Protection ◽  
Mouse Liver ◽  
Fetal Liver ◽  
Protection Effect ◽  
Fetal Mouse ◽  
Fetal Mouse Liver ◽  
Irradiation Protection

Abstract Various methods of freezing have been evaluated for the preservation of the radiation protection effect in fetal mouse liver. The best results were obtained with tissue frozen slowly in glycerol to -80 C., stored at -50 C. or lower, and thawed rapidly. Other variables such as the size of the tissue particles, the amount of serum in the freezing mixture, and the method of dilution did not influence the results.

Evaluation of the Fibrin Plate Method for Estimating Plasminogen Activators

1972 ◽  
Vol 28 (01) ◽  
pp. 075-088 ◽  
Author(s):  
N. A Marsh ◽  
C. L Arocha-Pinango
Keyword(s):  
Tranexamic Acid ◽  
Plasminogen Activators ◽  
Heated Plate ◽  
Plasminogen Activation ◽  
Response Curves ◽  
Plate Method ◽  
Single Plate ◽  
Effect Of Additives ◽  
Threefold Increase ◽  
Fibrin Plate

SummaryA study was carried out in order to evaluate the Astrup and Mullertz fibrin plate method for estimating plasminogen activators.Choice of a suitable fibrinogen substrate was found to be the most important factor in setting up a workable assay. Many preparations contained a large proportion of non-clottable protein and plates made from these fibrinogens were usually unreliable. In addition, plasminogen content varied appreciably between preparations so that sensitivity of the method required careful calibration with each new batch of fibrinogen.The effect of additives in the fibrin plate was considered and it was found that calcium chloride alone was sufficient to ensure a stabilised plate which could be stored at 4° C for some time. The addition of tranexamic acid (AMCHA) was found to be a slightly more convenient way of estimating direct proteolytic activity, compared with the traditional heated plate. However neither method distinguished completely between proteolysis and plasminogen activation.In order to improve the precision of the method, the use of an analysis of variance technique has been studied. This technique provides information on the dose-response curves of test and unknown substances, and in addition produces an approximately threefold increase in precision over single plate tests.

Effect of Additives on High Temperature Deformation in Cubic Zirconia (Y-CSZ)

2008 ◽  
Vol 57 (6) ◽  
pp. 543-547
Author(s):  
Takuma WADA ◽  
Takahiro KAKEI ◽  
Hiroyuki HORII ◽  
Takeshi SHIONO ◽  
Yasunori OKAMOTO
Keyword(s):  
High Temperature ◽  
High Temperature Deformation ◽  
Temperature Deformation ◽  
Cubic Zirconia ◽  
Effect Of Additives

Solid State Analysis and Theoretical Explorations on Polymorphic and Hydrate Forms of p-Hydroxybenzaldehyde Isonicotinichydrazone: Effect of Additives on Polymorphic Crystallization

2018 ◽  
Author(s):  
Lincy Tom ◽  
Victoria A. Smolenski ◽  
Jerry P. Jasinski ◽  
M.R. Prathapachandra Kurup
Keyword(s):  
Hirshfeld Surface ◽  
Framework Analysis ◽  
Reaction Conditions ◽  
Space Groups ◽  
Effect Of Additives ◽  
Ft Ir ◽  
Packing Arrangement ◽  
The Stability ◽  
Ir And Raman ◽  
Isonicotinic Hydrazide

The reaction of p-hydroxybenzaldehyde with an equimolar amount of isonicotinic hydrazide afforded two polymorphic and hydrate forms of p-hydroxybenzaldehyde isonicotinichydrazone (HBIH) by varying the experimental reaction conditions. The compounds are fully characterized by means of single crystal and powder diffraction methods, vibrational spectroscopy (FT-IR and Raman), thermal and elemental analysis. The compound crystallizes in three different forms in two different space groups, P21/c (form PA and PB) and Pbca (PC). The Hirshfeld surface analysis shows the differences in the relative contributions of intermolecular interactions to the total Hirshfeld surface area for the HBIH molecules. The calculated pairwise interaction energies (104-116 kJ/mol) can be related to the stability of the crystals. Energy framework analysis identifies the interaction hierarchy and their topology. The geometry and conformation of the three forms are essentially similar which differ only by packing arrangement.

Solid State Analysis and Theoretical Explorations on Polymorphic and Hydrate Forms of p-Hydroxybenzaldehyde Isonicotinichydrazone: Effect of Additives on Polymorphic Crystallization

2018 ◽  
Author(s):  
Lincy Tom ◽  
Victoria A. Smolenski ◽  
Jerry P. Jasinski ◽  
M.R. Prathapachandra Kurup
Keyword(s):  
Hirshfeld Surface ◽  
Framework Analysis ◽  
Reaction Conditions ◽  
Space Groups ◽  
Effect Of Additives ◽  
Ft Ir ◽  
Packing Arrangement ◽  
The Stability ◽  
Ir And Raman ◽  
Isonicotinic Hydrazide

The reaction of p-hydroxybenzaldehyde with an equimolar amount of isonicotinic hydrazide afforded two polymorphic and hydrate forms of p-hydroxybenzaldehyde isonicotinichydrazone (HBIH) by varying the experimental reaction conditions. The compounds are fully characterized by means of single crystal and powder diffraction methods, vibrational spectroscopy (FT-IR and Raman), thermal and elemental analysis. The compound crystallizes in three different forms in two different space groups, P21/c (form PA and PB) and Pbca (PC). The Hirshfeld surface analysis shows the differences in the relative contributions of intermolecular interactions to the total Hirshfeld surface area for the HBIH molecules. The calculated pairwise interaction energies (104-116 kJ/mol) can be related to the stability of the crystals. Energy framework analysis identifies the interaction hierarchy and their topology. The geometry and conformation of the three forms are essentially similar which differ only by packing arrangement.

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