scholarly journals Studies of the Irradiation Protection Effect of Fetal Liver in Mice. I. Influence of the Gestational Age of the Donor Tissue

Blood ◽  
1961 ◽  
Vol 18 (2) ◽  
pp. 182-186 ◽  
Author(s):  
PAUL N. TSCHETTER ◽  
JOHN H. GITHENS ◽  
M. GIOVANNELLA MOSCOVICI
Keyword(s):  
Gestational Age ◽  
Fetal Liver ◽  
Second Trimester ◽  
Hematopoietic Tissue ◽  
Third Trimester ◽  
Protection Effect ◽  
Late Mortality ◽  
Donor Tissue ◽  
Level Of Significance ◽  
Irradiation Protection

Abstract 1. The gestational age of donor hematopoietic tissue appeared to have no influence on the 30-day mortality following homologous transplants in irradiated mice. 2. Recipients of second trimester homologous donor tissue had a late (90-day) mortality that was 16 per cent lower than that observed in animals receiving tissue from third trimester and neonatal donors, but statistical analysis showed a low level of significance. 3. Irradiation alone appeared to cause a late mortality in non-injected irradiated animals and in isologously transplanted irradiated animals.

scholarly journals Normal value of pulsatility index of umbilical artery in second and third trimester of pregnancy

2013 ◽  
Vol 39 (1) ◽  
pp. 42-44 ◽  
Author(s):  
MA Ferdous ◽  
MM Sharif ◽  
AS Mohiuddin ◽  
F Shegufta
Keyword(s):  
Gestational Age ◽  
Pulsatility Index ◽  
Umbilical Artery ◽  
Negative Relationship ◽  
Cross Sectional Study ◽  
Third Trimester ◽  
Cross Sectional ◽  
Mean Values ◽  
The Mean ◽  
Level Of Significance

This cross sectional study was carried out on 60 pregnant Bangladeshi women in the department of Radiology and Imaging, BIRDEM for measurement of Pulsatility Index (PI) of umbilical artery of their fetuses by duplex colour Doppler sonography during 2nd and 3rd trimester of pregnancies. Considering total 2nd and 3rd trimesters the mean PI value of umbilical artery was 1.24 (SD±0.27). While considering the gestational in separate trimesters, study showed that the value of PI in 2nd trimester was 1.33 (SD±0.29) and in 3rd trimester PI was 1.18 (SD±0.25). Paired t test shows there was a highly significant (t=35.79, df=59, Level of significance=0.001) difference between mean values of PI in different gestational ages. It was observed that there was gradual decrease of PI value with increase of gestational age (r= -0.207) but this decrease of PI was not statistically significant (p=0.113). Regression analysis between dependent PI value and independent gestational age showed linear negative relationship but this was not statistically significant (p=0.11). This study revealed that the Pulsatility index of umbilical artery was decreased with increase of gestational age from 2nd to 3rd trimester. DOI: http://dx.doi.org/10.3329/bmrcb.v39i1.15809 Bangladesh Med Res Counc Bull 2013; 39: 42-44

scholarly journals Maternal Serum Levels of Alpha Tumour Necrotic Factor, Interleukin 10, Interleukin 6 and Interleukin 4 in Malaria Infected Pregnant Women Based on Their Gestational Age in Southeast, Nigeria

2020 ◽  
pp. 64-70
Author(s):  
Obeagu, Emmanuel Ifeanyi ◽  
Esimai, Bessie Nonyelum ◽  
Ekelozie, Ifeoma Stella ◽  
Asogwa Eucharia Ijego ◽  
Amaeze Augustine Amaeze ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Gestational Age ◽  
First Trimester ◽  
Interleukin 10 ◽  
Interleukin 4 ◽  
Second Trimester ◽  
Third Trimester ◽  
Tnf Α ◽  
Significant Difference ◽  
Tumour Necrotic Factor

Malaria has been reported as a condition caused by infestation with Plasmodium parasite species, is a major public health problem globally especially in developing countries like Nigeria. This study was carried out in Federal Medical Centre Umuahia in Abia State, Nigeria. A study was done to determine the maternal serumlevels of alpha tumour necrotic factor, interleukin 10, interleukin 6and interleukin 4 in malaria infected pregnant women based on their gestational age in Southeast, Nigeria. A total of 150 subjects between the ages of 18-45 years were recruited for the study comprising of fifty (50) subjects each of the 3 trimesters. Commercial ELISA Kit by MELSIN Medical Co Limited was used to measure all the cytokines. The results of Table 1 showed no significant difference of TNF-α (p=0.346), IL-10 (p=0.059), IL-6 (p=0.811) and IL-4 (p=0.257) of malaria infected pregnant women at first trimester and second trimester respectively. The results of Table 2 showed no significant difference of TNF-α (p=0.642), IL-10 (p=0.678), IL-6 (p=0.551) and IL-4 (p=0.280) of malaria infected pregnant women at first trimester and third trimester respectively. The results of Table 2 showed no significant difference of TNF-α (p=0.062), IL-10 (p=0.016), IL-6 (p=0.352) and IL-4 (p=0.914) of malaria infected pregnant women at first trimester and third trimester respectively. The study showed no changes in the cytokines studied among the malaria infected pregnant women based on gestational ages except when IL-10 was compared between the subjects on second trimester and third trimester. This study shows that malaria infection does not changes these cytokines in pregnant women based on gestational ages except the il-10 when compared at second trimester and third trimester but changes when compared at other trimesters.

scholarly journals Comparison of the Ultrasonic Evaluation of Bi-Parietal Diameter and Femoral Length in 2nd and 3rd Trimester to Estimate the Gestational Age

2021 ◽  
Vol 49 (3) ◽  
pp. 43-48
Author(s):  
Farjana Akther ◽  
Borhan Uddin ◽  
Mahbuba Ahmed ◽  
Kazi Nazma Begum ◽  
Nasrin Akhter ◽  
...  
Keyword(s):  
Correlation Coefficient ◽  
Gestational Age ◽  
Second Trimester ◽  
Third Trimester ◽  
Femoral Length ◽  
Medical College ◽  
Gestational Period ◽  
Ultrasonic Evaluation ◽  
History Of ◽  
Two Parameters

During the gestational period, fetal biometrics are assessed through ultrasonography to observe the growth of the fetus. This study observed the corresponding of gestational age those were measured by two of the fetal diameters; gestational age were calculated from history of last menstrual period (LMP), in the last two trimesters. This descriptive type of observational study was carried out in the Department of Radiology and Imaging of Dhaka Medical College and Hospital, during the period of July, 2004 to June, 2005. Here 291 single-ton, non-complicated pregnant women of LMP were selected purposively from valid record. Bi-parietal diameter (BPD) and femoral length (FL) estimated through ultrasonography. These two parameters compared with the gestational age in second and third trimester. The study found that, before 36th week, the BPD based gestational age varied 2 to 3 days from LMP based gestational age and after that, the variation was 1 to 4 weeks. In case of FL, the ultrasonic measurement found to be 2 to 4 days backward in the second trimester and 2 to 3 days advance in the last trimester in contrast to the LMP based gestational age. In the second trimester, it has been found that, BPD has been the superior predictor of the gestational age than the FL with the correlation coefficient of 0.999 in case of BPD and 0.998 in case of FL when correlated with LMP based gestational age. Although, in third trimester, FL versus BPD predicted the gestational age with a correlation coefficient of 0.998 versus 0.978 respectively, when correlated with gestational age based on the history of LMP. This study has observed that, later in pregnancy, FL has the better predictability over BPD to determine the gestational age. Bangladesh Med J. 2020 Sept; 49(3) : 43-48

scholarly journals Lipid Profile of Healthy Women During Normal Pregnancy

2009 ◽  
Vol 28 (3) ◽  
pp. 152-160 ◽  
Author(s):  
Margarita Diareme ◽  
Petros Karkalousos ◽  
Georgos Theodoropoulos ◽  
Stefanos Strouzas ◽  
Nikos Lazanas
Keyword(s):  
Pregnant Women ◽  
Lipid Profile ◽  
Gestational Age ◽  
First Trimester ◽  
Normal Pregnancy ◽  
Second Trimester ◽  
Third Trimester ◽  
Predisposing Factor ◽  
Healthy Women ◽  
C 30

Lipid Profile of Healthy Women During Normal PregnancyThe four basic lipid indexes (Chol, Trig, HDL-C and LDL-C) increase during pregnancy, following different rates of increase. Among the four analytes triglycerides show the largest increase and HDL-C the smallest. All analyte values are raised during the 40 weeks of pregnancy, except HDL-C which is stabilized during the second trimester. After delivery the values decrease, except LDL-C which remains steady (for some weeks) before starting to fall following the others. In this study the relations between the four lipid indexes and some predisposing factors (age, gestational age, nationality, body mass index, profession, smoking and diabetes during pregnancy) were investigated. The sample consisted of 413 pregnant women, mainly Greeks and Albanians. After regression analysis it was proved that the only common predisposing factor was the gestational age. Triglycerides and total cholesterol are also influenced by the women's age. The lipid indexes showed no important difference between the pregnant women in the first trimester and the non-pregnant women. On the contrary, there was a statistical difference between the pregnant women in the second and third trimester and between them and the women in the first trimester. The percentages of increase between first and second trimester were: Chol: 38%, Trig: 115%, HDL-C: 30%, LDL-C: 33%. The percentages of increase between first and third trimester were: Chol: 65%, Trig: 208%, HDL-C: 26%, LDLC: 64%.

scholarly journals Down-regulation of PM20D1 is associated with clinics outcomes and prognosis of gestational patients with diabetes mellitus

2021 ◽  
Author(s):  
Lieming Zhang
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Age ◽  
Pregnancy Outcomes ◽  
Serum Levels ◽  
Inflammatory Factors ◽  
Second Trimester ◽  
Third Trimester ◽  
Tnf Α ◽  
Patients With Diabetes ◽  
Healthy Control

IntroductionTo investigate clinic role of PM20D1 in gestational diabetes mellitus (GDM).Material and methodsThis observational study included 189 cases of GDM patients who came to our department during March 2018 to December 2019. Additionally, 100 healthy pregnant individuals who came to physical examination were included as healthy control during the same period. Western blotting was used to determine the expression of PM20D1 at gestational age 24-28 weeks, as well as gestational age 37-40 weeks. Serum inflammatory factors of C reactive protein (CRP), interleukin (IL)-1β, IL-6, and tumor necrosis factor (TNF)-α.ResultsThe expression of PM20D1 was markedly decreased in GDM patients compared with the healthy control. Besides, patients of third trimester of pregnancy (gestational age 37-40 weeks) showed significantlylower expression of PM20D1 than patients of second trimester of pregnancy (gestational age 24-28 weeks). Serum levels of CRP, IL-1β, IL-6, TNF-α and leptin were remarkably higher and levels of adiponectin were markedly lower in GDM patients at both second and third trimester of pregnancy, which were the highest at third trimester of pregnancy. Pearson’s analysis showed PM20D1 was negatively correlated with IL-1β, IL-6 and leptin and positively correlated with adiponectin. At second trimester of pregnancy, patients with lower expression of PM20D1 showed remarkably higher levels of HOMA-IR, fasting insulin, FBG, OGTT-1hPG, OGTT-2hPG, as well as TG and LDL-ch, as well as markedly lower levels of HDL-ch. Down-regulated PM20D1 predicted poor pregnancy outcomes.ConclusionsReduced was PM20D1 associated with patients’ clinics outcomes and pregnancy outcomes in GDM.

scholarly journals Fetal Ductus Venosus Pulsatility Index and Diameter during Second and Third Trimester of Gestation

2017 ◽  
Vol 56 (205) ◽  
pp. 124-131 ◽  
Author(s):  
Pratit Pokharel ◽  
Mukhtar Alam Ansari
Keyword(s):  
Gestational Age ◽  
Pulsatility Index ◽  
Fetal Liver ◽  
Umbilical Vein ◽  
Vena Cava ◽  
Cross Sectional Study ◽  
Ductus Venosus ◽  
Third Trimester ◽  
Cross Sectional ◽  
The Mean

Introduction: The ductus venosus is a small funnel shaped vessel found posterior to the fetal liver connecting the intra-abdominal umbilical vein and the inferior vena cava. It is one of the three physiological shunts in the fetus. The main objective of this study is to construct the reference table and normogram for fetal ductus venosus Pulsatility Index and diameter with gestational age. Methods: This was a prospective cross sectional study conducted during August 2011 to July 2012 taking 294 uncomplicated pregnancies using systemic random sampling method. Three measurements were made for ductus venosus diameter and Pulsatility Index in each fetus during period of fetal quiescence. Results: The ductus venosus diameter at <20weeks, 20-25 weeks, 25-30 weeks, >30 weeks were 1.16, 1.31, 1.62, 1.81 and Pulsatility Index at <20weeks, 20-25 weeks, 25-30 weeks, >30 weeks were 0.41, 0.44, 0.41 and 0.41 respectively. Conclusions: The mean diameter of the ductus venosus was linear across gestational age. The Pulsatility Index shows a scattered distribution across the gestational age. Keywords: ductus venosus diameter; gestational age; Pulsatility Index.

scholarly journals A correlation of trans cerebellar diameter by ultrasonography and gestational age in second and third trimester

2018 ◽  
Vol 6 (2) ◽  
pp. 55-59
Author(s):  
Ankur Shah ◽  
Manish Kumar Shah
Keyword(s):  
Standard Deviation ◽  
Perinatal Mortality ◽  
Gestational Age ◽  
Second Trimester ◽  
Third Trimester ◽  
Mortality Incidence ◽  
Reliable Parameter ◽  
The Mean ◽  
Linear Manner ◽  
Singleton Pregnancies

Background and Objectives: Increased perinatal mortality incidence has been seen amongst patients whose precise gestational age is unknown. Trans cerebellar diameter is a newer parameter in the estimation of gestational age. Therefore, the present study was conducted with the aim to determine the accuracy of trans cerebellar diameter in predicting gestational age during second and third trimester of pregnancy. Materials and Methods: The present study was conducted in the Mithila Hospital,Janakpurdham for a period of 1 year. The study included a total of 160 females with singleton pregnancies during their 2nd or 3rd trimester. The characteristic butterfly appearance of the cerebellum hinted the location of posterior fossa. All the data was arranged in a tabulated form and analyzed statistically. Data was expressed in the form of mean with standard deviation. SPSS software16 was used for the analysis of the data. Results: The present study enrolled 160 subjects, out of which 80 were in their second trimester and 80 were in their third trimester.  The mean transcerebellar diameter of subjects in second trimester was 20.22±4.87 and it was 36.01±2.89 amongst subjects in their third trimester. As the gestational age advances, the transcerebellar diameter also increases with it in a linear manner. Conclusion: Transcerebellar diameter can be used as a reliable parameter to estimate the gestational age and is also not altered in cases of intrautering growth restriction.

Midwifery Care for Pregnant Women With Back Pain Discomfort in Trimester III Pregnancy at the Karunia Birth Clinic, Sidoarjo.

Academia Open ◽  
2021 ◽  
Vol 5 ◽  
Author(s):  
Anggraeni Kriswidya Putri ◽  
Hanik Machfudloh
Keyword(s):  
Back Pain ◽  
Data Collection ◽  
Pregnant Women ◽  
Gestational Age ◽  
Analysis Data ◽  
Second Trimester ◽  
Third Trimester ◽  
Midwifery Care ◽  
The Third ◽  
Maternity Clinic

Pregnancy is a process that begins with the unification of spermatozoa with ovum called fertilization and then continued with implantation. Normal pregnancies generally last for 9 months, and are divided into the first 3 trimesters 1-12 weeks, the second trimester 13-27 weeks, the third trimester 28-40 weeks. Various complaints felt by pregnant women, one of which is back pain that causes pregnant women discomfort. This aerikel was written taken from the place of Maternity Clinic Karunia Sidoarjo on January 05, 2020. The way of data collection is by means of anamnesa, examination of analysis, data then documenting by comparing between the data that has been obtained with existing theories. Mrs. .m 40 weeks gestational age, with complaints of physiological back pain with good maternal and fetal conditions.

scholarly journals The role of three-dimensional ultrasound in pregnancies submitted to cerclage

2018 ◽  
Vol 64 (7) ◽  
pp. 620-626
Author(s):  
Thais da Fonseca Borghi ◽  
Mário Henrique Burlacchini de Carvalho ◽  
Antonio Gomes de Amorim Filho ◽  
Silvio Martinelli ◽  
Marcelo Zugaib ◽  
...  
Keyword(s):  
Gestational Age ◽  
Cox Regression ◽  
Three Dimensional ◽  
Cervical Length ◽  
Second Trimester ◽  
Regression Analyses ◽  
Third Trimester ◽  
The Third ◽  
Gestational Age At Birth ◽  
Age At Birth

SUMMARY OBJECTIVE: Cervical cerclage is the standard treatment for cervical incompetence (CI); however, there is still a high risk of preterm birth for women who undergo this treatment. The aim of this study was to longitudinally evaluate findings on two-dimensional transvaginal ultrasonography (2DTVUS) and three-dimensional transvaginal ultrasonography (3DTVUS) that could be related to gestational age at birth. METHODS: A total of 68 pregnant women who were treated with cerclage were evaluated by 2DTVUS and 3DTVUS in the second and third trimesters of pregnancy. Log-rank tests and Cox regression analyses were used to identify significant findings related to gestational age at delivery. RESULTS: A cervical length lower than 281 mm (p= 0.0083), a proximal cervical length lower than 10 mm (p= 0.0151), a cervical volume lower than 18.17 cm3 (p= 0.0152), a vascularization index (VI) under 2.153 (p= 0.0044), and a vascularization-flow index (VFI) under 0.961 (p= 0.0059) in the second trimester were all related to earlier delivery. In the third trimester, a cervical length lower than 20.4 mm (p= 0.0009), a VI over 0.54 (p= 0.0327) and a VFI over 2.275 (p= 0.0479) were all related to earlier delivery. Cervical funnelling in the second and third trimesters and proximal cervical length in the third trimester were not related to gestational age at birth. The COX regression analyses showed that cervical volume in the second trimester; FI and VFI in the third trimester were significantly associated with gestational age at birth. CONCLUSION: In women treated with history-indicated cerclage or ultrasound-indicated cerclage, 2nd trimester cervical volume and 3rd trimester FI and VFI are independent significant sonographic findings associated with time to delivery.

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