Organ-on-a-chip and 3D printing as preclinical models for medical research and practice

Author(s):  
Abhishek Jain ◽  
Tanmay Mathur ◽  
Navaneeth K.R. Pandian ◽  
Amirali Selahi
Author(s):  
L. Gelda ◽  
L. Nesterovich

The problem of adequate diagnostic tools use for suicide risk assessment т medical research and practice is of extreme importance because of the high incidence of suicide in the population of psychotic patients and the high vulnerability of the latter to the known risk factors. The article provides ап overview of the existing psychometric instruments (scales) used to assess the risk of suicide in psychiatry as well as in general medicine.


PEDIATRICS ◽  
1991 ◽  
Vol 88 (3) ◽  
pp. 637-639
Author(s):  
OLLE JANE Z. SAHLER

Resource allocation is of increasing concern as we seek to provide necessary services to our citizens within the confines of balanced budgets. Of particular interest to those allocating resources is the issue of efficiency or cost effectiveness (cost/those who benefit). Although budgetary constraints tend to focus attention on cost effectiveness, consideration of program effectiveness (the number of people who actually benefit/those who theoretically could benefit), itself, must be a primary concern of medical research and practice. Without this information, we cannot be assured that our patients are receiving the best care possible, let alone secure funding for programs that promise the best return for each dollar spent.


2021 ◽  
Author(s):  
◽  
C. A. Romero Zepeda

The development of different types of Organ on a Chip has attract the attention of pharmaceutical industry to develop alternative methods for ensuring the efficiency of drugs before approval. A dual bioprinting-culturing system was developed to construct the needed elements needed for creating three dimensional tissues including the corresponding instrumented device that may keep the environment conditions that may reinforce the cells´ growth. The proposed 3D printing platform considering the principles of an Organ on a Chip for the creation of a hybrid system of scaffolds for tissue engineering using polylactic acid. The usage of the 3D printing method allows the modification and creation of a flexible platform with different structures to a low cost, including the possibility of introducing the structural elements to create multi component tissues. The developed system was tested using a traditional fibroblasts culture.


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