Switchable green solvents for lipids extraction from microalgae

Understanding the miscibility behavior of ionic liquid (IL) / monomer, IL / polymer and IL / nanoparticle mixtures is critical for the use of ILs as green solvents in polymerization processes, and to rationalize recent observations concerning the superior solubility of some proteins in ILs when compared to standard solvents. In this work, the most relevant results obtained in terms of a three-component Flory-Huggins theory concerning the “Extra Solvent Power, ESP” of ILs when compared to traditional non-ionic solvents for monomeric solutes (case I), linear polymers (case II) and globular nanoparticles (case III) are presented. Moreover, useful ESP maps are drawn for the first time for IL mixtures corresponding to case I, II and III. Finally, a potential pathway to improve the miscibility of non-ionic polymers in ILs is also proposed.

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Ionic Liquids for Topical Delivery in Cancer

Current Medicinal Chemistry ◽

10.2174/0929867325666181026110227 ◽

2020 ◽

Vol 26 (41) ◽

pp. 7520-7532 ◽

Cited By ~ 4

Author(s):

Ana Rita Dias ◽

João Costa-Rodrigues ◽

Cátia Teixeira ◽

Cristina Prudêncio ◽

Paula Gomes ◽

...

Keyword(s):

Ionic Liquids ◽

Clinical Applications ◽

Great Promise ◽

Topical Drug Delivery ◽

Green Solvents ◽

2Nd Generation ◽

Windows Of Opportunity ◽

Pharmaceutical Technology ◽

Skin Cancers ◽

Per Se

: The unique properties of ionic liquids make them quite appealing for diverse applications, from “green” solvents (1st generation ionic liquids) to finely tuned materials (2nd generation ionic liquids). A decade ago, a 3rd generation of ionic liquids emerged which is focused on their prospective clinical applications, either as drugs per se or as adjuvants in drug formulations. In recent years, research focused on the use of ionic liquids for topical drug delivery has been increasing and holds great promise towards clinical application against skin cancers. This article highlights the growing relevance of ionic liquids in medicinal chemistry and pharmaceutical technology, which is opening new windows of opportunity.

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Green Solvents in Organic Synthesis: An Overview II

Current Organic Chemistry ◽

10.2174/1385272820666160209212804 ◽

2016 ◽

Vol 20 (15) ◽

pp. 1576-1583 ◽

Cited By ~ 6

Author(s):

Karem Shanab ◽

Catharina Neudorfer ◽

Helmut Spreitzer

Keyword(s):

Organic Synthesis ◽

Green Solvents

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Green Chemistry and Green Solvents: An Overview

Current Green Chemistry ◽

10.2174/2213346107999200709132815 ◽

2020 ◽

Vol 7 (3) ◽

pp. 314-325

Author(s):

Barla Karuna Devi ◽

Swathi Naraparaju ◽

Chaganti Soujanya ◽

Sayan Dutta Gupta

Keyword(s):

Ionic Liquids ◽

Green Chemistry ◽

Chemical Reaction ◽

Supercritical Co2 ◽

Environmental Problems ◽

Green Solvents ◽

Eutectic Mixtures ◽

Organic Carbonates

: Green chemistry emphasizes designing novel routes to overcome health and environmental problems that occur during a chemical reaction. Green solvents are used in place of conventional solvents that are hazardous to both human and the environment. Solvents like water, ionic liquids, supercritical CO2, biosolvents, organic carbonates, and deep eutectic mixtures can be used as green solvents. The review focuses on the properties, applications, and limitations of these solvents.

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Sustainable synthesis of AFe2O4 (A= Mg, Zn, Mn) catalysts: comparing the photooxidative and electrochemical properties towards organic dyes detection and degradation

New Journal of Chemistry ◽

10.1039/d1nj01367j ◽

2021 ◽

Author(s):

Jeena N. Baby ◽

Lavanya Chandrasekar ◽

Sea-Fue Wang ◽

Sriram Balasubramanian ◽

Ashwini Anantharaman ◽

...

Keyword(s):

Electrochemical Properties ◽

Organic Dyes ◽

Energy Requirements ◽

Green Solvents ◽

Reaction Media

By serving as alternatives to toxic and hazardous solvents, green solvents assist in implementing the idea of sustainability. The use of these neoeric reaction media dramatically reduces energy requirements and...

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Green extraction of proteins, umami and other free amino acids from brown macroalgae Ascophyllum nodosum and Fucus vesiculosus

Journal of Applied Phycology ◽

10.1007/s10811-021-02569-y ◽

2021 ◽

Author(s):

Viruja Ummat ◽

Marco Garcia-Vaquero ◽

Mahesha M. Poojary ◽

Marianne N. Lund ◽

Colm O’Donnell ◽

...

Keyword(s):

Amino Acids ◽

Citric Acid ◽

Free Amino Acids ◽

Free Amino ◽

Food Industry ◽

Ascophyllum Nodosum ◽

Fucus Vesiculosus ◽

Green Solvents ◽

Brown Macroalgae ◽

Extraction Solvent

AbstractSeaweeds are a valuable potential source of protein, as well as free amino acids (FAAs) with umami flavour which are in high demand by the food industry. The most commonly used flavouring agents in the food industry are chemically synthesised and therefore are subject to concerns regarding their safety and associated consumer resistance. This study focuses on the effects of extraction time (1 and 2 h) and solvents (0.1 M HCl, 1% citric acid and deionised water) on the extraction of protein and FAAs including umami FAAs from Irish brown seaweeds (Ascophyllum nodosum and Fucus vesiculosus). Extraction yields were influenced by both the extraction solvent and time, and also varied according to the seaweed used. Both seaweeds investigated were found to be good sources of protein, FAAs including umami FAAs, demonstrating potential application as flavouring agents in the food industry. Overall, the use of green solvents (deionised water and citric acid) resulted in higher recoveries of compounds compared to HCl. The results of this study will facilitate the use of more sustainable solvents in industry for the extraction of proteins and flavouring agents from seaweed.

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Green Solvents as an Alternative to DMF in ZIF-90 Synthesis

Molecules ◽

10.3390/molecules26061573 ◽

2021 ◽

Vol 26 (6) ◽

pp. 1573

Author(s):

Aljaž Škrjanc ◽

Ciara Byrne ◽

Nataša Zabukovec Logar

Keyword(s):

Room Temperature ◽

Product Yield ◽

Solvent Exchange ◽

Green Solvents ◽

Zeolitic Imidazolate Framework ◽

Short Treatment ◽

Molar Ratios ◽

Primary Particles ◽

High Product Yield

The use of green solvents as an alternative to dimethylformamide (DMF) in the synthesis of zeolitic imidazolate framework-90 (ZIF-90) was investigated. Two biobased aprotic dipolar solvents CyreneTM and γ-valerolactone (GVL) proved to successfully replace DMF in the synthesis at room temperature with a high product yield. While the CyreneTM—based product shows reduced porosity after activation, the use of GVL resulted in materials with preserved crystallinity and porosity after activation, without prior solvent exchange and a short treatment at 200 °C. The primary particles of 30 nm to 60 nm in all products further form agglomerates of different size and interparticle mesoporosity, depending on the type and molar ratios of solvents used.

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Technologies and Extraction Methods of Polyphenolic Compounds Derived from Pomegranate (Punica granatum) Peels. A Mini Review

Processes ◽

10.3390/pr9020236 ◽

2021 ◽

Vol 9 (2) ◽

pp. 236

Author(s):

Dimitrios Lampakis ◽

Prodromos Skenderidis ◽

Stefanos Leontopoulos

Keyword(s):

Electric Fields ◽

Bioactive Compounds ◽

New Technologies ◽

Ohmic Heating ◽

Punica Granatum ◽

Extraction Methods ◽

Added Value ◽

Green Solvents ◽

Ultrasound Assisted Extraction ◽

Functional Product

The interest in using plant by-product extracts as functional ingredients is continuously rising due to environmental and financial prospects. The development of new technologies has led to the achievement of aqueous extracts with high bioactivity that is preferable due to organic solvents nonuse. Recently, widely applied and emerging technologies, such as Simple Stirring, Pressure-Applied Extraction, Enzymatic Extraction, Ultrasound-Assisted Extraction, Pulsed Electric Fields, High Hydrostatic Pressure, Ohmic Heating, Microwave Assistant Extraction and the use of “green” solvents such as the deep eutectic solvents, have been investigated in order to contribute to the minimization of disadvantages on the extraction of bioactive compounds. This review is focused on bioactive compounds derived from pomegranate (Punica granatum) peels and highlighted the most attractive extraction methods. It is believed that these findings could be a useful tool for the pomegranate juices industry to apply an effective and economically viable extraction process, transforming a by-product to a high added value functional product.

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