Role of Carboxylesterases in Therapeutic Intervention of Nerve Gas Poisoning

2009 ◽  
pp. 1033-1040 ◽  
Author(s):  
Sigrun Hanne Sterri ◽  
Frode Fonnum
Keyword(s):  
Therapeutic Intervention ◽  
Gas Poisoning ◽  
Nerve Gas

The Role of Cellular Senescence in Werner Syndrome: Toward Therapeutic Intervention in Human Premature Aging

2007 ◽  
Vol 1100 (1) ◽  
pp. 455-469 ◽  
Author(s):  
T. DAVIS ◽  
F. S. WYLLIE ◽  
M. J. ROKICKI ◽  
M. C. BAGLEY ◽  
D. KIPLING
Keyword(s):  
Cellular Senescence ◽  
Therapeutic Intervention ◽  
Werner Syndrome ◽  
Premature Aging

FIRST-AID TREATMENT FOR NERVE-GAS POISONING

The Lancet ◽  
1952 ◽  
Vol 260 (6740) ◽  
pp. 886
Author(s):  
H.M. Garner
Keyword(s):  
First Aid ◽  
Gas Poisoning ◽  
Nerve Gas

Vaso-occlusion in sickle cell disease: pathophysiology and novel targeted therapies

Hematology ◽  
2013 ◽  
Vol 2013 (1) ◽  
pp. 362-369 ◽  
Author(s):  
Deepa Manwani ◽  
Paul S. Frenette
Keyword(s):  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Targeted Therapies ◽  
Therapeutic Intervention ◽  
Fetal Hemoglobin ◽  
Cell Disease ◽  
The Past ◽  
Symptomatic Management

Abstract Recurrent and unpredictable episodes of vaso-occlusion are the hallmark of sickle cell disease. Symptomatic management and prevention of these events using the fetal hemoglobin–reactivating agent hydroxyurea are currently the mainstay of treatment. Discoveries over the past 2 decades have highlighted the important contributions of various cellular and soluble participants in the vaso-occlusive cascade. The role of these elements and the opportunities for therapeutic intervention are summarized in this review.

Modern Concepts on the Role of Inflammation in Pulmonary Fibrosis

2011 ◽  
Vol 135 (6) ◽  
pp. 780-788 ◽  
Author(s):  
Robert J. Homer ◽  
Jack A. Elias ◽  
Chun Gun Lee ◽  
Erica Herzog
Keyword(s):  
Cell Death ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Therapeutic Intervention ◽  
Macrophage Polarization ◽  
Critical Evaluation ◽  
Clinical Context ◽  
Disease Biomarkers ◽  
Unpublished Research

Abstract Context.—Idiopathic pulmonary fibrosis is a uniformly lethal disease with limited biomarkers and no proven therapeutic intervention short of lung transplantation. Pulmonary fibrosis at one time was thought to be a result of inflammation in the lung. Although some forms of pulmonary fibrosis may result from inflammation, idiopathic pulmonary fibrosis is currently thought to result from cell death primarily and inflammation secondarily. Objective.—To determine the role of inflammation in pulmonary fibrosis in light of our laboratory's published and unpublished research and published literature. Data Sources.—Review based on our laboratory's published and unpublished experimental data with relevant background and clinical context provided. Conclusions.—Although cell death is central to pulmonary fibrosis, the proper cytokine environment leading to macrophage polarization is also critical. Evaluation of this environment is promising both for the development of disease biomarkers and for targets for therapeutic intervention.

Medical Versus Surgical Treatment of Primary Vesicoureteral Reflux

PEDIATRICS ◽  
1981 ◽  
Vol 67 (3) ◽  
pp. 392-400 ◽  
Keyword(s):  
Surgical Treatment ◽  
Vesicoureteral Reflux ◽  
Therapeutic Intervention ◽  
Renal Damage ◽  
Rational Basis ◽  
Benefit Ratio ◽  
International Trial ◽  
Prospective Longitudinal ◽  
Primary Vesicoureteral Reflux

The role of VUR in the development and progression of renal damage in children is universally acknowledged. The risk/benefit ratio of therapeutic intervention, whether medical or surgical, continues to be debated. This carefully controlled prospective, longitudinal, multispecialty, international trial aims to establish a rational basis for the treatment of VUR.

scholarly journals The psychotherapeutic role of the nurse in a psychodynamic unit

Curationis ◽  
1981 ◽  
Vol 4 (2) ◽  
Author(s):  
Gail Riccitelli
Keyword(s):  
Group Work ◽  
Therapeutic Intervention ◽  
Specific Reference ◽  
Therapeutic Communities ◽  
Psychiatric Nurse ◽  
Community Work ◽  
Individual Basis

A great deal has been written on the importance of therapeutic communities in the practise of psychiatry. This article proposes to highlight the extent to which the role of the psychiatric nurse has been developed in such a community. By considering aspects such as therapeutic dynamics, therapeutic intervention on an individual basis, group work and community work with specific reference to the nurse, attention will be drawn to the awvheon uise sw iwllhinicgh t ea rree loinpqeuni stho hthere rnouler saes, custodian and don the cloak of therapist.

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