Quality control and discrimination of Pericarpium Citri Reticulatae and Pericarpium Citri Reticulatae Viride based on high-performance liquid chromatographic fingerprints and multivariate statistical analysis

2007 ◽  
Vol 588 (2) ◽  
pp. 207-215 ◽  
Author(s):  
Lun-zhao Yi ◽  
Da-lin Yuan ◽  
Yi-zeng Liang ◽  
Pei-shan Xie ◽  
Yu Zhao
Keyword(s):  
Quality Control ◽  
Statistical Analysis ◽  
Multivariate Statistical Analysis ◽  
High Performance ◽  
High Performance Liquid Chromatographic ◽  
Multivariate Statistical ◽  
Chromatographic Fingerprints ◽  
Liquid Chromatographic

scholarly journals High-Performance Liquid Chromatographic Fingerprint for Quality Control of Terminalia arjuna Containing Ayurvedic churna Formulation

2009 ◽  
Vol 92 (4) ◽  
pp. 1016-1020 ◽  
Author(s):  
Sohan S Chitlange ◽  
Prajakta S Kulkarni ◽  
Dada Patil ◽  
Bhushan Patwardhan ◽  
Rabindra K Nanda
Keyword(s):  
Quality Control ◽  
High Performance ◽  
Raw Materials ◽  
High Performance Liquid Chromatographic ◽  
Raw Material ◽  
Terminalia Arjuna ◽  
Hplc Fingerprint ◽  
Ayurvedic Drugs ◽  
Quality Control Tool ◽  
Liquid Chromatographic

Abstract Because Ayurvedic herbal preparations contain a myriad of compounds in complex matrixes, it is difficult to establish quality control standards for raw materials and to standardize finished Ayurvedic drugs. A novel, accurate, and valid fingerprint method was developed using HPLC for quality control of a traditional Ayurvedic Arjuna churna formulation, which is used as a cardiotonic drug. Comprehensive comparison of chromatograms of standardized formulation of Arjuna churna and marketed formulations revealed eight characteristic peaks in chromatograms, which unambiguously confirmed the presence of authentic raw material used in the formulation on the basis of their retention time values and UV data. An HPLC fingerprint was also developed for total sapogenins present in Terminalia arjuna. The six common peaks observed in chromatograms of isolated sapogenins, standardized formulations, and marketed formulations can serve as a quality control tool for qualitative estimation of total saponin glycosides present in an Arjuna churna formulation.

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