Mathematical modeling of the receptor-mediated endocytosis process of targeted therapeutic agents in drug delivery systems

2020 ◽  
Vol 79 ◽  
pp. 300-313
Author(s):  
Jong Hyuk Byun ◽  
Il Hyo Jung
2016 ◽  
Vol 4 (11) ◽  
pp. 1535-1553 ◽  
Author(s):  
Arti Vashist ◽  
Ajeet Kaushik ◽  
Atul Vashist ◽  
Rahul Dev Jayant ◽  
Asahi Tomitaka ◽  
...  

Hydrogel based drug delivery systems owe excellent potential as targeted drug delivery systems for the delivery of therapeutic agents and diagnostics for major infectious diseases.


World Science ◽  
2020 ◽  
Vol 1 (6(58)) ◽  
pp. 32-37 ◽  
Author(s):  
Olga Bilan ◽  
Iryna Brubaker ◽  
Kateryna Marchenko-Tolsta

The review investigates the latest developments in the field of application of nanotechnologies in the transportation of therapeutic agents, features and the advantages of using nanoscale drug delivery systems for the treatment of diseases, as well as further prospects of using this field in medicine. Modern drug delivery systems are characterized by target orientation, rapid response to the environment and the use of biocompatible and biodegradable nanomaterials which allow for the development of the next generation of more effective drugs. Interdisciplinary research in this fast-growing field provides opportunities to design and develop multifunctional devices that can accurately target and successfully administer the release and distribution of active ingredients in the body.


2013 ◽  
Vol 18 (1) ◽  
pp. 46-62 ◽  
Author(s):  
Chong T. Ying ◽  
Juntian Wang ◽  
Robert J. Lamm ◽  
Daniel T. Kamei

2013 ◽  
Vol 18 (1) ◽  
pp. 34-45 ◽  
Author(s):  
Garrett L. Mosley ◽  
Cameron D. Yamanishi ◽  
Daniel T. Kamei

2017 ◽  
Vol 2017 ◽  
pp. 1-10 ◽  
Author(s):  
Huu Ngoc Nguyen ◽  
Santa Romero Jovel ◽  
Tu Hoang Khue Nguyen

Nanotechnology has the ability to target specific areas of the body, controlling the drug release and significantly increasing the bioavailability of active compounds. Organic and inorganic nanoparticles have been developed for drug delivery systems. Many delivery systems are through clinical stages for development and market. Minicell, a nanosized cell generated by bacteria, is a potential particle for drug delivery because of its size, safety, and biodegradability. Minicells produced by bacteria could drive therapeutic agents against cancer, microbial infection, and other diseases by targeting. In addition, minicells generated by lactic acid bacteria being probiotics are more interesting than others because of their benefits like safety, immunological improvement, and biodegradation. This review aims to highlight the stages of development of nanoparticle for drug delivery and discuss their advantages and limitations to clarify minicells as a new opportunity for the development of potential nanoparticle for drug delivery.


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