Synthesis of biomedical composite scaffolds by laser sintering: Mechanical properties and in vitro bioactivity evaluation

2014 ◽  
Vol 297 ◽  
pp. 1-8 ◽  
Author(s):  
Fwu-Hsing Liu
2014 ◽  
Vol 24 (6) ◽  
pp. 2073-2080 ◽  
Author(s):  
Zikai Han ◽  
Pei Feng ◽  
Chengde Gao ◽  
Yang Shen ◽  
Cijun Shuai ◽  
...  

2015 ◽  
Vol 47 (1) ◽  
pp. 31-39 ◽  
Author(s):  
Y. Cao ◽  
B. Yang ◽  
C. Gao ◽  
P. Feng ◽  
C. Shuai

As the only bioactive material that can bond with both hard tissues and soft tissues, bioactive glass has become much important in the field of tissue engineering. 13-93 bioactive glass scaffolds were fabricated via selective laser sintering (SLS). It was focused on the effects of laser sintering on microstructure and mechanical properties of the scaffolds. The experimental results showed that the sintered layer gradually became dense with the laser power increasing and then some defects occurred, such as macroscopic caves. The optimum compressive strength and fracture toughness were 21.43?0.87 MPa and 1.14?0.09 MPa.m1/2, respectively. In vitro bioactivity showed that there was the bone-like apatite layer on the surface of the scaffolds after soaking in simulated body fluid (SBF), which was further evaluated by Fourier transform infrared spectroscopy (FTIR). Moreover, cell culture study showed MG-63 cells adhered and spread well on the scaffolds, and proliferated with increasing time in cell culture. These indicated excellent bioactivity and biocompatibility of nano 13-93 glass scaffolds.


Author(s):  
Wen-Fan Chen ◽  
Yu-Sheng Tseng ◽  
Yu-Man Chang ◽  
Ji Zhang ◽  
Yun-Han Su ◽  
...  

2016 ◽  
Vol 103 ◽  
pp. 10-24 ◽  
Author(s):  
A.R. Rafieerad ◽  
A.R. Bushroa ◽  
B. Nasiri-Tabrizi ◽  
J. Vadivelu ◽  
S. Baradaran ◽  
...  

10.30544/403 ◽  
2018 ◽  
Vol 24 (4) ◽  
Author(s):  
Tamara Matic ◽  
Maja Ležaja Zebić ◽  
Ivana Cvijović-Alagić ◽  
Vesna Miletić ◽  
Rada Petrović ◽  
...  

The aim of this study was to investigate the possibility of modifying model BisGMA/TEGDMA dental composite by substituting 10 wt. % of conventional glass fillers with bioactive fillers based on calcinated nanosized hydroxyapatite (HAp) and Mg doped hydroxyapatite (Mg-HAp). HAp and Mg-HAp powders were synthesized hydrothermally. Mechanical properties: hardness by Vickers (HV) and flexural strength (Fs) were tested initially and after being stored for 28 days in simulated body fluid (SBF). The experimental composites with HAp and Mg-HAp particles showed no statistically significant difference in HV compared to the control (p>0.05) either initially or after storage. Although mean Fs values of modified composites tested initially were lower (62 MPa) than those of the control (72 MPa), after 28 days of storage in SBF Fs values were greater for modified composites (42 MPa control sample, 48 MPa HAp and Mg-HAp samples). In vitro bioactivity of BisGMA/TEGDMA composites with HAp and Mg-HAp particles after 28 days in SBF was not detected. Keywords: hydroxyapatite; magnesium; dental composite; mechanical properties;


2019 ◽  
Vol 6 (7) ◽  
pp. 075212 ◽  
Author(s):  
Rasha A Youness ◽  
Mohammed A Taha ◽  
Amany A El-Kheshen ◽  
Nabil El-Faramawy ◽  
Medhat Ibrahim

Materials ◽  
2019 ◽  
Vol 12 (17) ◽  
pp. 2650
Author(s):  
Jae-Won Choi ◽  
Woo-Youl Maeng ◽  
Young-Hag Koh ◽  
Hyun Lee ◽  
Hyoun-Ee Kim

This study demonstrates the utility of camphene as the pore-regulating agent for phase separation-based 3D plotting to produce hierarchical macro/micro-porous poly(ε-caprolactone) (PCL)–calcium phosphate (CaP) composite scaffolds, specifically featuring highly microporous surfaces. Unlike conventional particulate porogens, camphene is highly soluble in acetone, the solvent for PCL polymer, but insoluble in coagulation medium (water). In this study, this unique characteristic supported the creation of numerous micropores both within and at the surfaces of PCL and PCL–CaP composite filaments when using high camphene contents (40 and 50 wt%). In addition, the incorporation of the CaP particles into PCL solutions did not deteriorate the formation of microporous structures, and thus hierarchical macro/micro-porous PCL–CaP composite scaffolds could be successfully produced. As the CaP content increased, the in vitro biocompatibility, apatite-forming ability, and mechanical properties (tensile strength, tensile modulus, and compressive modulus) of the PCL–CaP composite scaffolds were substantially improved.


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