Association between single limb standing test results and healthcare costs among community-dwelling older adults

Background: Epigenetic age acceleration has been studied as a promising biomarker of age-related conditions, including cognitive aging. This pilot study aims to explore potential cognitive aging-related biomarkers by investigating the relationship of epigenetic age acceleration and cognitive function and by examining the epigenetic age acceleration differences between successful cognitive aging (SCA) and normal cognitive aging (NCA) among Korean community-dwelling older adults (CDOAs). Methods: We used data and blood samples of Korean CDOAs from the Korean Frailty and Aging Cohort Study. The participants were classified into two groups, SCA (above the 50th percentile in all domains of cognitive function) and NCA. The genome-wide DNA methylation profiling array using Illumina Infinium MethylationEPIC BeadChip was used to calculate the following: the DNA methylation age, universal epigenetic age acceleration, intrinsic epigenetic age acceleration (IEAA), and extrinsic epigenetic age acceleration (EEAA). We also used Pearson correlation analysis and independent t-tests to analyze the data. Results: Universal age acceleration correlated with the Frontal Assessment Battery test results ( r = −0.42, p = 0.025); the EEAA correlated with the Word List Recognition test results ( r = −0.41, p = 0.027). There was a significant difference between SCA and NCA groups in IEAA ( p = 0.041, Cohen’s d = 0.82) and EEAA ( p = 0.042, Cohen’s d = 0.78). Conclusions: Epigenetic age acceleration can be used as a biomarker for early detection of cognitive decline in Korean community-dwelling older adults. Large longitudinal studies are warranted.

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Building Trust in Ethnically Diverse Older Adults Using Technology-Based Physio-Feedback

Innovation in Aging ◽

10.1093/geroni/igaa057.1851 ◽

2020 ◽

Vol 4 (Supplement_1) ◽

pp. 562-562

Author(s):

Ladda Thiamwong

Keyword(s):

Older Adults ◽

Ethnically Diverse ◽

Community Dwelling ◽

Test Results ◽

Balance Performance ◽

Specific Objective ◽

Objective Feedback ◽

And Migration ◽

Changes Over Time ◽

Community Dwelling Older Adults

Abstract There is no research exploring how to build trust in the context of falls risk assessment and prevention. This study describes strategies to build trust in ethnically diverse older adults using technology-based physio-feedback from two studies. The technology includes a portable BTrackS balance plate and BTrackS Balance Software running on a computer device. Participants were provided instant playback showing their static balance performance with a scale from 0 to 100. Sixty-seven community-dwelling older adults participated in the first study, and 41 of them (61.2%) participated again in the second study using the same procedures. 70% were women, 43% were immigrants, 34% Hispanics, 15% African Americans, and 9% Asians. Three reasons for participation were reported: 1) specific objective feedback on the test results that supported by technology, 2) ability to record changes over time; and 3) ability to access the fall risk technology-based test at a place of their convenience. Part of a symposium sponsored by the International Aging and Migration Interest Group.

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The Geriatric Nutritional Risk Index predicts increased healthcare costs and hospitalization in a cohort of community-dwelling older adults: Results from the MONICA/KORA Augsburg cohort study, 1994–2005

Nutrition ◽

10.1016/j.nut.2010.06.005 ◽

2011 ◽

Vol 27 (5) ◽

pp. 534-542 ◽

Cited By ~ 16

Author(s):

Sebastian E. Baumeister ◽

Beate Fischer ◽

Angela Döring ◽

Wolfgang Koenig ◽

Astrid Zierer ◽

...

Keyword(s):

Older Adults ◽

Cohort Study ◽

Healthcare Costs ◽

Risk Index ◽

Community Dwelling ◽

Nutritional Risk ◽

Geriatric Nutritional Risk Index ◽

Nutritional Risk Index ◽

Community Dwelling Older Adults

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Normative Fitness Performance Scores of Community-Dwelling Older Adults in Spain

Journal of Aging and Physical Activity ◽

10.1123/japa.20.1.106 ◽

2012 ◽

Vol 20 (1) ◽

pp. 106-126 ◽

Cited By ~ 12

Author(s):

Narcís Gusi ◽

Josue Prieto ◽

Pedro R. Olivares ◽

Serafin Delgado ◽

Fabian Quesada ◽

...

Keyword(s):

Older Adults ◽

Descriptive Study ◽

Community Dwelling ◽

Body Fat Percentage ◽

Test Results ◽

Fat Percentage ◽

Cross Sectional ◽

Age Related ◽

Specific Assessment ◽

Community Dwelling Older Adults

A cross-sectional descriptive study was designed to obtain normative age-specific fitness scores for the general population of community-dwelling older adults in Spain. In total, 6,449 participants (5,610 women and 839 men) age 60–99 yr who lived in the region of Extremadura were recruited. Compared with the cohorts of similar studies in other countries, this cohort had more physically inactive elderly participants and participants with a higher body-fat percentage. All test results declined as age increased. Sex differences in the age-related decline in fat and body mass were observed. Women scored better in the flexibility tests, and men performed better in the other tests. These data may be highly useful for the age-specific assessment of the fitness performance of older adults and the design of programs that promote functional ability in older adults.

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