It is known that there are especially risk factors, and clinical course of acute myocardial infarction in men and women in different age groups

Aims: This study looks at trends in event rates of first and recurrent fatal and non-fatal acute myocardial infarction (AMI), and 28-day case fatality in AMI within the Northern Sweden MONICA area. Methods: The AMI event rate and 28-day case fatality in acute myocardial infarction were registered between 1985 and 1998 in the two northernmost counties in Sweden in men and women in the age groups 25 - 64 years. Results: Statistically significant mean annual decreases were found in fatal and non-fatal combined event rates (4% for men and 2.3% for women), fatal event rate (7.1% for men and 5% for women), fatal first acute myocardial infarction (7.1% for men and 4.4% for women), and both non-fatal and fatal recurrent AMI for both sexes (5.5% for both men and women for non-fatal and, for fatal AMI, 7.1% for men and 5.7% for women). In addition, there were significant decreases for men in non-fatal event rate (2.4%), and non-fatal first AMI (1.4%). The decreases in case fatality were small, especially so for women. Conclusions: There is a trend of decreasing event rates in both fatal and non-fatal AMI, and first and recurrent AMI, most pronounced for men. The case fatality also decreased although to a lesser degree, suggesting that the decreasing mortality in ischaemic heart disease mainly is caused by reduced disease incidence.

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Mortalidade por infarto agudo do miocárdio

Revista de Enfermagem UFPE on line ◽

10.5205/1981-8963-v12i2a230729p565-572-2018 ◽

2018 ◽

Vol 12 (2) ◽

pp. 565

Author(s):

Tatiana Laís Fonsêca de Medeiros ◽

Paloma Cibelle do Nascimento Silva de Andrade ◽

Rejane Marie Barbosa Davim ◽

Nicelha Maria Guedes dos Santos

Keyword(s):

Myocardial Infarction ◽

Acute Myocardial Infarction ◽

High Mortality ◽

Age Groups ◽

Mortality Rates ◽

Men And Women ◽

Southeast Region ◽

Chagas Cardiomyopathy ◽

The North ◽

Unified Health System

RESUMOObjetivo: descrever a mortalidade por infarto agudo do miocárdio. Método: estudo quantitativo, descritivo, exploratório, ecológico de série temporal, com a população de 30 a 59 anos de idade nas regiões do Brasil, no período de 2008 a 2016, de acordo com dados no Departamento de Informática do Sistema Único de Saúde. Resultados: verificou-se elevadas taxas de mortalidade por infarto agudo do miocárdio em homens e mulheres entre 30 e 59 anos. A região Sudeste com maior percentual de óbitos (47,9%), a Nordeste vem em seguida (20,2%), a região Sul com 14,8%, Centro-Oeste 9,1% e a Norte com 8%. Conclusão: os resultados mostram elevadas taxas de mortalidade por infarto agudo do miocárdio em homens e mulheres nas faixas etárias entre 30 e 59 anos revelando a região Sudeste com maior percentual (47,9%), liderando todas as regiões e faixas etárias. Conclui-se que o infarto agudo do miocárdio é uma doença desencadeada por fatores intrínsecos e que estes fatores podem ser modificados a partir de programas e medidas preventivas. Descritores: Cardiopatias Congênitas; Infarto do Miocárdio; Cardiopatia Chagásica; Doença Crônica; Dor no Peito; Fibrilação Ventricular.ABSTRACTObjective: To describe mortality due to an acute myocardial infarction. Method: this is a quantitative, descriptive, exploratory, ecological, time series study with the population aged 30 to 59 years old in the Brazilian Region from 2008 to 2016 according to data from the Department of Information Technology of the Unified Health System. Results: high mortality rates due to acute myocardial infarction in men and women between 30 and 59 years old was verified. The Southeast Region had the highest percentage of deaths (47.9%), then the Northeast followed (20.2%), the South Region (14.8%), the Central West (9.1%) and the North (8%). Conclusion: the results show high mortality rates due to acute myocardial infarction in men and women in the age groups between 30 and 59 years old, revealing the Southeast Region with the highest percentage (47.9%), leading all regions and age groups. It is concluded that acute myocardial infarction is a disease triggered by intrinsic factors and these factors can be modified from preventive programs and measures. Descriptors: Hearth Congenital; Myocardial Infarction; Chagas Cardiomyopathy; Chronic Disease; Chest Pain; Ventricular Fibrillation.RESUMENObjetivo: describir la mortalidad por infarto agudo del miocardio. Método: estudio cuantitativo, descriptivo, exploratorio, ecológico de serie temporal, con la población de 30 a 59 años de edad en las Regiones de Brasil en el período de 2008 a 2016 de acuerdo con datos en el Departamento de Informática del Sistema Único de Salud. Resultados: se verificaron elevadas tasas de mortalidad por infarto agudo del miocardio en hombres y mujeres entre 30 y 59 años. La Región Sudeste tuvo la mayor porcentaje de óbitos (47,9%), el Nordeste viene en seguida (20,2%), Região Sur con 14,8%, Centro-Oeste 9,1% y Norte con 8%. Conclusión: los resultados muestran elevadas tasas de mortalidad por infarto agudo del miocardio en hombres y mujeres en las edades entre 30 y 59 años revelando la Región Sudeste con mayor porcentaje (47,9%), liderando todas las regiones y eddades. Se concluye que el infarto agudo del miocardio es una enfermedad desencadenada por factores intrinsecos y estos factores pueden ser modificados a partir de programas y medidas preventivas. Descriptores: Cardiopatias Congénitas; Infarto del Miocardio; Cardiomiopatia Chagásica; Enfermedad Crónica; Dolor del Pecho; Fibrilación Ventricular.

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The effect of the presence of metabolic syndrome criteria on the post-infarction course in patients with acute myocardial infarction with ST-segment elevation

Ukrainian Journal of Cardiology ◽

10.31928/1608-635x-2020.3.6072 ◽

2020 ◽

Vol 27 (3) ◽

pp. 60-72

Author(s):

O. V. Shumakov ◽

O. M. Parkhomenko ◽

O. V. Dovhan ◽

O. S. Gurjeva

Keyword(s):

Risk Factors ◽

Myocardial Infarction ◽

Heart Failure ◽

Metabolic Syndrome ◽

Acute Myocardial Infarction ◽

Heart Rate ◽

Clinical Course ◽

Matching Criteria ◽

Group 1

The aim – to assess the additional prognostic information of metabolic syndrome (MS) components in groups of patients with acute myocardial infarction with segment elevation ST (STEMI), equalized in terms of commonly used acute coronary syndrome (ACS) risk factors. Materials and methods. Retrospective analysis of the 820 cases of STEMI included: evaluation of risk factors according to the scales TIMI, GRACE, PURSUIT, and evaluation of components of the metabolic syndrome at entry (the presence of diabetes mellitus and/or increasing glucose levels > 7 mmol/l, overweight, hypertension, dyslipidemia), as well as the assessment of the indicators of clinical course of hospital period of MI, treatment and results of follow-up of patients, including the information about cases of cardiac death. Results and discussion. Via automated «case-match-control» algorhythm from the basic cohort 2 groups were selected: group 1 (n=41, patients with MS) and group 2 (n=123, patients without MS). Matching criteria included following 13 risk factors: age, height, presence of heart failure, smoking, systemic hypotension at the 1 day of AMI, presence of anterior STEMI, the peak level of the MB-CK and AST, a history of angina and the period of unstable angina before STEMI, the presence of previous MI, baseline heart rate, baseline glomerular filtration rate (CKD-EPI), male gender. Groups were exactly matched by the first 4 matching criteria, and among other criteria maximum mismatch of 3 criteria was allowed (mean mismatch was 1.87 criteria from 13 per pair, and there were no significant differences in groups by each of 13 matching criteria). Otherwise, group 1 was characterized by more severe baseline profile, clinical course of hospital period, but it has the more intensive medical treatment also (including more frequent prescription of ACE inhibitors). According to the follow-up data, patients in group 1 had smaller end-systolic and end-diastolic indexes, more signed improvement in acute heart failure rate, higher heart rate variability and smaller dispersion of repolarisation at the 10th day. Also there was observed a trend toward a lower 3-year mortality (4,9 versus 17,1 %; p=0.05). Conclusions. The presence of MS accompanying STEMI is associated with poorer course of acute period of the disease and, in a contrary, with more favorable course of post-infarction period because of more intensive cardiac therapy in this group of patients.

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The events registration and survey procedures in the Northern Sweden MONICA Project

Scandinavian Journal of Public Health ◽

10.1080/14034950310001441 ◽

2003 ◽

Vol 31 (61_suppl) ◽

pp. 9-17 ◽

Cited By ~ 109

Author(s):

Birgitta Stegmayr ◽

Vivan Lundberg ◽

Kjell Asplund

Keyword(s):

Risk Factors ◽

Myocardial Infarction ◽

Acute Myocardial Infarction ◽

Population Based ◽

Northern Sweden ◽

Mortality Trends ◽

Men And Women ◽

Suspected Stroke ◽

Old Men ◽

Monica Project

Introduction: The WHO MONICA Project (Multinational Monitoring of Trends and Determinants in Cardiovascular Disease) was initiated in 1982. The purpose was to evaluate to what extent mortality trends could be explained by changes over time in the population load of conventional cardiovascular risk factors. To test this hypothesis, time trends in cardiovascular event rates have been correlated with trends in levels of risk factors in 35- to 64-year-old men and women in 38 populations. In most MONICA populations, the study has covered a period of 10 years or more. Methods: All acute myocardial infarction and stroke events have been registered in a population-based setting in Norrbotten and Västerbotten counties from 1985 and onwards. The total population is approximately 510,000 inhabitants. In the frame of the WHO MONICA Project, the same strict criteria have been used in all years. Another part of the MONICA Project is population risk factor surveys. In Northern Sweden the first survey took place in 1986 and the following surveys were performed in 1990, 1994, and 1999, including the age group 25 - 74 years (the first two surveys were of the age range 25 - 64 years). Results: From 1985 to 2000, in total 18,105 suspected stroke events, aged 25 - 74 years, were scrutinized and validated at the central stroke office in Northern Sweden. Of these, 13,908 were found to fulfil the MONICA criteria of an acute stroke. During the period 1985 to 1998, in total 13,228 cases of suspected acute myocardial infarction, aged 25 - 64 years, were registered. Of these, 8,744 fulfilled the MONICA criteria for acute myocardial infarction. In the four surveys, in total 9,000 randomly selected men and women were invited for survey. Of these 6,952 (77%) participated in the surveys. Conclusion: From 1985 and onwards, the WHO MONICA project has been going on in Northern Sweden. During the whole time the same strict WHO criteria have been followed.

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Trends in incident acute myocardial infarction in Norway: An updated analysis to 2014 using national data from the CVDNOR project

European Journal of Preventive Cardiology ◽

10.1177/2047487318780033 ◽

2018 ◽

Vol 25 (10) ◽

pp. 1031-1039 ◽

Cited By ~ 15

Author(s):

Gerhard Sulo ◽

Jannicke Igland ◽

Stein Emil Vollset ◽

Marta Ebbing ◽

Grace M Egeland ◽

...

Keyword(s):

Myocardial Infarction ◽

Acute Myocardial Infarction ◽

Confidence Interval ◽

Incidence Rate ◽

Rate Ratio ◽

Incidence Rate Ratio ◽

Age Groups ◽

Incidence Rates ◽

Myocardial Infarctions ◽

Men And Women

Background We updated the information on trends of incident acute myocardial infarction in Norway, focusing on whether the observed trends during 2001–2009 continued throughout 2014. Methods All incident (first) acute myocardial infarctions in Norwegian residents age 25 years and older were identified in the Cardiovascular Disease in Norway 1994–2014 project. We analysed overall and age group-specific (25–64 years, 65–84 years and 85 + years) trends by gender using Poisson regression analyses and report the average annual changes in rates with their 95% confidence intervals. Results During 2001–2014, 221,684 incident acute myocardial infarctions (59.4% men) were identified. Hospitalised cases accounted for 79.9% of all incident acute myocardial infarctions. Overall, incident acute myocardial infarction rates declined on average 2.6% per year (incidence rate ratio 0.974, 95% confidence interval 0.972–0.977) in men and 2.8% per year (incidence rate ratio 0.972, 95% confidence interval 0.971–0.974) in women, contributed by declining rates of hospitalisations (1.8% and 1.9% per year in men and women, respectively) and deaths (6.0% and 5.8% per year in men and women, respectively). Declining rates were observed in all three age groups. The overall acute myocardial infarction incidence rates continued to decline from 2009 onwards, with a steeper decline compared to 2001–2009. During 2009–2014, gender-adjusted acute myocardial infarction incidence among adults age 25–44 years declined 5.3% per year, contributed mostly by declines in hospitalisation rates (5.1% per year). Conclusion Acute myocardial infarction incidence rates continued to decline after 2009 in Norway in both men and women. The decline started to involve individuals aged 25–44 years, marking a turning point in the previously reported stagnation of rates during 2001–2009.

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STUDY OF RISK FACTORS AND CLINICAL PROFILE OF ACUTE MYOCARDIAL INFARCTION IN FEMALES

10.36106/ijar/2402223 ◽

2021 ◽

pp. 65-68

Author(s):

Bhaurao D. Nakhale ◽

Jitendra P. Bhagat ◽

Abhijit Y. Nugurwar

Keyword(s):

Physical Activity ◽

Risk Factors ◽

Myocardial Infarction ◽

Acute Myocardial Infarction ◽

Chest Pain ◽

Central Obesity ◽

Age Group ◽

Men And Women ◽

History Of ◽

Artery Disease

Cardiovascular disease is the most important health issue facing mankind and continues to be major cause of morbidity and mortality.Women are disproportionately affected by coronary artery disease(CAD) compared with men.There are different clinical presentations of heart disease and acute myocardial infarction in women than in men.Also different studies shows that there is difference in the major cardiovascular risk factors amongst men and women at younger age.The present study was undertaken with a view to understand the clinical prole of acute myocardial infarction in women and observe the variations in acute myocardial infarction between men and women. Materials and methods-This observational and analytical study includes 118 female cases of acute myocardial infarction admitted to ICCU and randomly selected 118 male cases of acute myocardial infarction admitted to ICCU during the same tenure.Various necessary th investigations were carried out and risk factors of acute myocardial infarction were determined.All the cases were followed up on the 7 day of admission and one month after discharge from the hospital for various complications.Data thus collected was analysed at the end of study. Results-Maximum number of female cases were in age group 60-69 years(45.6%)while maximum number of male cases were in age group 50- 59 years(33.05%).Anterior wall myocardial infarction was the commonest type of acute myocardial infarction in both groups.ST elevation myocardial infarction was more common in males(94.9%)as compared to females(83.89%) whereas non ST elevation myocardial infarction was common in females(10%) as compared to males (5%).Atypical chest pain was more common in female cases(50.8%)whereas typical chest pain was more common with male cases(52.4%).Also dyspnoea as presenting symptom was signicantly more in female cases(51.6%)as compared to male cases(20.3%).Among the risk factors as Diabetes mellitus,signicant difference was observed in female(45.7%) vs male cases(30.5%).Other risk factors like lack of physical activity was signicantly more in female cases(84.7%) as compared to male cases(50%).Central obesity and family history of CAD were more common in female cases . 42(35.6%) female cases had arrthymias during hospital stay as compared to 50(42.4%) male cases.Post MI angina was present in 21 (20.38%) female cases and 12(11.11%) male cases during one month follow up.Mortality was more common in female cases(12.7%) compared with the male cases(8.47%)but it was not statistically signicant. Females suffer from coronary artery disease slightly at older age Conclusions- as compared to males.Atypical chest pain and dyspnoea are more common presenting symptoms in females compared to males.Diabetes mellitus,central obesity, lack of physical activity and family history of CAD are most common risk factors in female cases for acute myocardial infarction.ST elevation myocardial infarction is less common in females as compared to males.Complications like congestive cardiac failure ,arrthymias are more common in females as compared to males.The overall mortality with acute myocardial infarction are common in females than males.

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