Effect Of Omega-3 Polyunsaturated Fatty Acids On Endothelial Function, Leptin Level, Blood Lipid Profile In Patients With Coronary Heart Disease In Combination With Non-Alcoholic Steatosis.

2019 ◽  
Vol 287 ◽  
pp. e145
Author(s):  
M. Grechanyk
Keyword(s):  
Fatty Acids ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Endothelial Function ◽  
Polyunsaturated Fatty Acids ◽  
Lipid Profile ◽  
Blood Lipid ◽  
Omega 3 ◽  
Blood Lipid Profile

Krill oil to improve blood lipids status in advanced cancer patient with cachexia.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e19634-e19634
Author(s):  
Roberto Serpe ◽  
Clelia Madeddu ◽  
Filomena Panzone ◽  
Giorgia Antoni ◽  
Maria Chiara Cau ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Cancer Cachexia ◽  
Blood Lipid ◽  
Blood Levels ◽  
Krill Oil ◽  
Omega 3 ◽  
Blood Lipid Profile ◽  
Cholesterol Levels

e19634 Background: Cancer patients with cachexia symptoms often show a lipid profile disorder, consisting in severe hypertriglyceridemia due to increased circulating free fatty acids and variable total cholesterol levels, decreased activity of lipoprotein lipase and increased lipolysis, which is correlated with proinflammatory cytokines levels, particularly IL-6 and TNFα. Recent evidence further confirms impairment of adipose tissue metabolism in inflammatory condition like cancer cachexia. The aim of this study was to assess the effect of nutritional supplementation with Omega 3 fatty acids (EPA and DHA) in the form of Krill Oil, on main parameters of blood lipid profile and on IL-6 and TNFα blood levels. Methods: In 2011, 34 IV stage cachectic patients (M/F 20/14; age range 55-85 y) with cancer at different sites were enrolled. 21 healthy subjects were studied as controls. All patients had high blood tryglicerides, low total cholesterol levels , high levels of blood IL-6 and TNFα compared to controls. Patients received 3 capsules (3 g/day) of krill oil (Superba™ Krill Oil, Aker Biomarine, Norway), which is an oil extract from the crustacean krill (Euphausia Superba) which contains Omega-3 series unsaturated fatty acids in phospholipidic form, of which 98 % are EPA and DHA mainly in phospholipid form. Treatment duration was 2 months. Results: A significant reduction of tryglicerides blood levels (148.23 ± 88.06 vs 114 ± 55.8 mg/dl) and a significant improvement of HDL cholesterol (42.5 ± 15.6 vs 60.9 ± 12.3 mg/dl) and Total Cholesterol (135.6 ± 46.3 vs 159 ± 41.1 mg/dl) was observed after treatment. Cytokines Il-6 and TNFα blood levels did not change significantly after treatment Conclusions: Nutritional supplementation with krill oil showed a positive activity in the regulation of blood lipid profile, involving different metabolic and inflammatory pathways, probably mainly affecting hormone-sensitive lipase activity. Our data suggest that krill oil could be useful in multi-targeted combined pharmaco-nutritional approaches to treat cancer-cachexia. Additional phase III clinical studies are warranted.

The combined use of pravastatin omega-3-polyunsaturated fatty acids (PuFA) and antioxidants in the therapy of coronary heart disease (CHD)

2000 ◽  
Vol 151 (1) ◽  
pp. 144
Author(s):  
I.G. Fomina ◽  
O.L. Belaya ◽  
V.I. Kalmykova ◽  
I.P. Rudakova ◽  
E.N. Gavrilova ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Polyunsaturated Fatty Acids ◽  
Omega 3 ◽  
Combined Use

Clinical effect of omega-3-polyunsaturated fatty acids (PuFA) and antioxidants in the therapy of the coronary heart disease (CHD)

2000 ◽  
Vol 151 (1) ◽  
pp. 144
Author(s):  
O.L. Belaya ◽  
V.I. Kalmykova ◽  
I.G. Fomina ◽  
L.A. Ivanova ◽  
E.V. Zakharova ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Polyunsaturated Fatty Acids ◽  
Clinical Effect ◽  
Omega 3

PP200-MON REGULAR CONSUMPTION OF FUNCTIONAL OIL ENRICHED WITH OMEGA 3 FATTY ACIDS FROM FISH OIL IMPROVES THE BLOOD LIPID PROFILE IN OBESE PEOPLE

2012 ◽  
Vol 7 (1) ◽  
pp. 217
Author(s):  
B. López Plaza ◽  
L.M. Bermejo ◽  
L. Zurita Rosa ◽  
D. Rodríguez Duran ◽  
S. Palma Milla ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fish Oil ◽  
Lipid Profile ◽  
Blood Lipid ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Obese People ◽  
Blood Lipid Profile ◽  
Regular Consumption

scholarly journals Analisis asupan karbohidrat dan lemak serta aktivitas fisik terhadap profil lipid darah pada penderita penyakit jantung koroner

2020 ◽  
Vol 5 (2) ◽  
pp. 179
Author(s):  
Novi Dwi Yanti ◽  
Suryana Suryana ◽  
Yulia Fitri
Keyword(s):  
Physical Activity ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Lipid Profile ◽  
Blood Lipid ◽  
Lipid Profiles ◽  
The Body ◽  
World Health ◽  
Blood Lipid Profile ◽  
Activity Data

World Health Organization has estimated that the main cause of death in degenerative diseases is coronary heart disease (CHD). Coronary heart disease can be caused by narrowing of the blood vessels due to high levels of fat in the blood. This is due to excessive intake of fat and carbohydrates, and not doing physical activity or the body is not moving. This study aims to determine the blood lipid profile of outpatients with coronary heart disease. This descriptive-analytic study was used as a case-control study design, with a sample of 64 outpatients. The study was conducted at the Meuraxa Hospital Banda Aceh in March 2019. Intake data were collected using the SQ-FFQ method and physical activity data using the PAL method, while HDL, LDL, and triglyceride data were obtained through secondary data from hospital medical records. The statistical test was used by the Chi-Square test. The results showed that there was an effect of fat intake on blood lipid profiles in coronary heart disease patients (p= 0,006 with OR= 4,80), and the effect of carbohydrate intake (p= 0,032 and OR= 2,96), on the contrary, physical activity (p= 0,130) with a lipid profile showed no association. In conclusion, the intake of fat and carbohydrates has an effect on blood lipid profiles, but physical activity does not affect the blood lipid profiles of patients with coronary heart disease. Suggestions, it is necessary to maintain a balance of consumption of foods that are high in fat, and it is necessary to do consultations regarding low-fat diets

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