scholarly journals Prevalence and relationship between metabolic syndrome and risk of cardiovascular disease: Evidence from two population-based studies

2020 ◽  
Vol 42 ◽  
pp. e41-e48
Author(s):  
Asiiat S. Alieva ◽  
Elena Olmastroni ◽  
Olga V. Reutova ◽  
Oxana P. Rotar ◽  
Alexandra O. Konradi ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Population Based

scholarly journals Gender discrepancy in the predictive effect of metabolic syndrome and its components on newly onset cardiovascular disease in elderly from rural China

2020 ◽  
Author(s):  
Shasha Yu ◽  
Xiaofan Guo ◽  
GuangXiao Li ◽  
Hongmei Yang ◽  
Liqiang Zheng ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Rural China ◽  
International Diabetes Federation ◽  
Heart Association ◽  
Population Based ◽  
Blood Institute ◽  
Effective Strategies ◽  
National Heart Lung ◽  
Predictive Effect

Abstract Background To evaluate the possible predictive effect of metabolic syndrome (MetS) and its components on cardiovascular disease (CVD) in a longitudinal analysis according to different criteria of MetS among rural Chinese elderly. Method A population-based sample of 2486 rural elderly Chinese residents aged ≥ 60 years at baseline were followed up from 2012–2013 to 2015–2017. CVD included stroke, coronary heart disease (CHD) diagnosed by clinicians were self-reported and were confirmed by medical records. MetS was diagnosed according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III), the American Heart Association/National Heart, Lung, and Blood Institute (AHA/NHLBI) and the international Diabetes Federation (IDF) criterion respectively. Result Hazard ratio adjusting for CHD, Stroke and CVD in those with MetS using NCEP ATP III criteria in female were 1.27 (95%CI 0.73, 2.21), 1.54 (95%CI 0.99, 2.40) and 1.45 (95%CI 1.00, 2.10); 1.33 (95%CI 0.77, 2.32), 1.44 (95%CI 0.92, 2.25) and 1.36 (95%CI 0.94, 1.97) with the AHA/NHLBI criteria; and 1.10 (95%CI 0.89,1.36), 1.62 (95%CI 1.03, 2.55) and 1.36 (95%CI 0.93, 1.97) with IDF criteria. Besides, abdominal obesity using the AHA/NHLBI criteria was significantly associated with the incidence of stroke (HR: 1.60; 95%CI 1.01, 2.52). However, among rural male elderly, neither MetS nor its components were capable of predicting newly onset CVD. Conclusion MetS is significantly associated with high incidence of CVD among rural female elderly only, and the incidence of CVD was evident only when MetS was defined using NCEP ATP III criterion. In order to reduce CVD among elderly in rural China, effective strategies to prevent, diagnose, and treating MetS should be made in time, especially among female.

scholarly journals Sex hormones, inflammation and the metabolic syndrome: a population-based study

2003 ◽  
pp. 601-608 ◽  
Author(s):  
DE Laaksonen ◽  
L Niskanen ◽  
K Punnonen ◽  
K Nyyssonen ◽  
TP Tuomainen ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Body Mass ◽  
Sex Hormones ◽  
Free Testosterone ◽  
Population Based ◽  
World Health ◽  
Inverse Association ◽  
The Metabolic Syndrome

OBJECTIVE: Mild hypoandrogenism in men is associated with features of the metabolic syndrome, but the association with the metabolic syndrome itself using an accepted definition has not been described. DESIGN: Men with the metabolic syndrome were identified and testosterone and sex hormone-binding globulin (SHBG) levels were determined in a population-based cohort of 1896 non-diabetic middle-aged Finnish men. RESULTS: Calculated free testosterone and SHBG were 11% and 18% lower (P<0.001) in men with the metabolic syndrome (n=345, World Health Organisation definition). After categorisation by tertiles and adjusting for age and body mass index, total and free testosterone and SHBG were inversely associated with concentrations of insulin, glucose, triglycerides, C-reactive protein (CRP) and CRP-adjusted ferritin and positively associated with high-density lipoprotein cholesterol. Men with free testosterone levels in the lowest third were 2.7 (95% confidence interval (CI) 2.0-3.7) times more likely to have the metabolic syndrome in age-adjusted analyses, and 1.7 (95% CI 1.2-2.4) times more likely even after further adjusting for body mass index. Exclusion of men with cardiovascular disease did not alter the association. The inverse association of SHBG with the metabolic syndrome was somewhat stronger. CONCLUSIONS: Low testosterone and SHBG levels were strongly associated not only with components of the metabolic syndrome, but also with the metabolic syndrome itself, independently of body mass index. Furthermore, sex hormones were associated with inflammation and body iron stores. Even in the absence of late-stage consequences such as diabetes and cardiovascular disease, subtle derangements in sex hormones are present in the metabolic syndrome, and may contribute to its pathogenesis.

Metabolic Syndrome and Cardiovascular Disease in Elderly People in Rural China: A Population-Based Study

2013 ◽  
Vol 61 (6) ◽  
pp. 1036-1038 ◽  
Author(s):  
Yajun Liang ◽  
Zhongrui Yan ◽  
Aiqin Song ◽  
Chuanzhu Cai ◽  
Binglun Sun ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Elderly People ◽  
Rural China ◽  
Population Based ◽  
Population Based Study

scholarly journals Metabolic Syndrome Does Not Improve the Prediction of 5-Year Cardiovascular Disease and Total Mortality Over Standard Risk Markers. Prospective Population Based Study

Medicine ◽  
2014 ◽  
Vol 93 (27) ◽  
pp. e212 ◽  
Author(s):  
Alejandro López-Suárez ◽  
Antonio Bascuñana-Quirell ◽  
Manuel Beltrán-Robles ◽  
Javier Elvira-González ◽  
Fernando Fernández-Palacín ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Total Mortality ◽  
Population Based ◽  
Risk Markers ◽  
Population Based Study ◽  
Standard Risk

scholarly journals Prevalence and relationship between metabolic syndrome and risk of cardiovascular disease: Evidence from two population-based studies.

2021 ◽  
Vol 331 ◽  
pp. e159
Author(s):  
A. Alieva ◽  
E. Olmastroni ◽  
O. Reutova ◽  
O. Rotar ◽  
A. Konradi ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Population Based

scholarly journals Physical activity attenuates cardiovascular risk and mortality in men and women with and without the metabolic syndrome – a 20-year follow-up of a population-based cohort of 60-year-olds

2020 ◽  
pp. 204748732091659
Author(s):  
Elin Ekblom-Bak ◽  
Mats Halldin ◽  
Max Vikström ◽  
Andreas Stenling ◽  
Bruna Gigante ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Disease Incidence ◽  
Population Based ◽  
Men And Women ◽  
All Cause Mortality ◽  
Old Men ◽  
Cardiovascular Disease Incidence

Aims The purpose of this study was to analyse the association of leisure-time physical activity of different intensities at baseline, and cardiovascular disease incidence, cardiovascular disease mortality and all-cause mortality in a population-based sample of 60-year-old men and women with and without established metabolic syndrome, for more than 20 years of follow-up. A secondary aim was to study which cardiometabolic factors may mediate the association between physical activity and long-term outcomes. Methods A total of 3693 participants (53% women) underwent physical examination and laboratory tests, completed an extensive questionnaire at baseline 1997–1999 and were followed until their death or until 31 December 2017. First-time cardiovascular disease events and death from any cause were ascertained through regular examinations of national registers. Results Metabolic syndrome prevalence was 23.0%. In metabolic syndrome participants, light physical activity attenuated cardiovascular disease incidence (hazard ratio = 0.71; 95% confidence interval 0.50–1.00) compared to sedentary (reference) after multi-adjustment. Moderate/high physical activity was inversely associated with both cardiovascular disease and all-cause mortality, but became non-significant after multi-adjustment. Sedentary non-metabolic syndrome participants had lower cardiovascular disease incidence (0.47; 0.31–0.72) but not significantly different cardiovascular disease (0.61; 0.31–1.19) and all-cause mortality (0.92; 0.64–1.34) compared to sedentary metabolic syndrome participants. Both light and moderate/high physical activity were inversely associated with cardiovascular disease and all-cause mortality in non-metabolic syndrome participants ( p<0.05). There were significant variations in several central cardiometabolic risk factors with physical activity level in non-metabolic syndrome participants. Fibrinogen mediated the protective effects of physical activity in non-metabolic syndrome participants. Conclusion Physical activity of different intensities attenuated cardiovascular risk and mortality in 60-year old men and women with metabolic syndrome during a 20-year follow-up.

scholarly journals Increased Prevalence of Metabolic Syndrome Associated with Rheumatoid Arthritis in Patients without Clinical Cardiovascular Disease

2010 ◽  
Vol 38 (1) ◽  
pp. 29-35 ◽  
Author(s):  
CYNTHIA S. CROWSON ◽  
ELENA MYASOEDOVA ◽  
JOHN M. DAVIS ◽  
ERIC L. MATTESON ◽  
VERONIQUE L. ROGER ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Waist Circumference ◽  
Health Assessment ◽  
Population Based ◽  
Logistic Regression Models ◽  
Large Joint ◽  
History Of

Objective.To examine whether patients with rheumatoid arthritis (RA) with no overt cardiovascular disease (CVD) have a higher prevalence of metabolic syndrome (MetS) than subjects without RA or CVD. We also examined whether RA disease characteristics are associated with the presence of MetS in RA patients without CVD.Methods.Subjects from a population-based cohort of patients who fulfilled 1987 American College of Rheumatology criteria for RA between January 1, 1980, and December 31, 2007, were compared to non-RA subjects from the same population. All subjects with any history of CVD were excluded. Waist circumference, body mass index (BMI), and blood pressure were measured during the study visit. Data on CVD, lipids, and glucose measures were ascertained from medical records. MetS was defined using NCEP/ATP III criteria. Differences between the 2 cohorts were examined using logistic regression models adjusted for age and sex.Results.The study included 232 RA subjects without CVD and 1241 non-RA subjects without CVD. RA patients were significantly more likely to have increased waist circumference and elevated blood pressure than non-RA subjects, even though BMI was similar in both groups. Significantly more RA patients were classified as having MetS. In RA patients, MetS was associated with Health Assessment Questionnaire Disability Index, large-joint swelling, and uric acid levels, but not with C-reactive protein or RA therapies.Conclusion.Among subjects with no history of CVD, patients with RA are more likely to have MetS than non-RA subjects. MetS in patients with RA was associated with some measures of disease activity.

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