Ceftriaxone crystallization and its potential role in kidney stone formation

2011 ◽  
Vol 406 (3) ◽  
pp. 396-402 ◽  
Author(s):  
Somchai Chutipongtanate ◽  
Visith Thongboonkerd
1993 ◽  
Vol 150 (2 Part 1) ◽  
pp. 310-312 ◽  
Author(s):  
Khashayar Sakhaee ◽  
Jean A. Harvey ◽  
Paulette K. Padalino ◽  
Peggy Whitson ◽  
Charles Y.C. Pak

Author(s):  
Devesh Raizada ◽  
Pragya Kumar ◽  
Tanya Singh ◽  
Trisha Pruthi ◽  
Riyadarshini Riyadarshini

Urolithiasis is a multifactorial disease with an incidence rate of more than one million cases reported annually in India. Various forms of the calculus have been reported to have 90-95% inorganic and 5% organic matter. Out of the major proteins that comprise this organic component of the matrix, albumin, and uromodulin are found to be the most abundant. Albumin is also the most abundant protein in the human blood serum where it plays the role of a transporter of hormones, fatty acids, and other compounds. The increased concentrations of albumin may significantly affect a patient’s susceptibility to kidney stone formation. The study of the role of albumin in urolithiasis could give us useful insights on its potential role in this disease and may add to the therapeutic repertoire of albumin.


2021 ◽  
pp. 105257
Author(s):  
Narjess Bostanghadiri ◽  
Pardis Ziaeefar ◽  
Fatemeh Sameni ◽  
Mohammad Mahmoudi ◽  
Ali Hashemi ◽  
...  

Author(s):  
Raymundo Alejandro Pérez-Hernández ◽  
Silvia Guadalupe Treviño-Moreno ◽  
Gilberto Arévalo- Martínez ◽  
Eduardo Sánchez -García ◽  
Catalina Leos-Rivas ◽  
...  

Background: In clinical therapy, there is no satisfactory drug available for treatment of urolithiasis, especially for the prevention of their recurrence. The aim of this work was to evaluate in vivo antiurolithic activity of methanolic extract of Berberis trifoliata leaves. Material and methods: Urolithiasis was induced in Wistar rats by zinc disc implantation in urinary bladder. Upon postsurgical recovery, different doses of the methanolic extract of B. trifoliata leaves (50, 100 and 150 mg/kg body weight) were administered orally to zinc disc implanted rats for a period of 20 days. Antiurolithiatic activity was evaluated by measuring the difference between the weight of the implanted zinc discs at the time of implantation and the final weight of the dried calculi taken out from the bladder at the end of the 20 days period of treatment. Results: Extract of B. trifoliata significantly reduced calculi deposition around the implanted zinc disc at all doses (50, 100, and 150 mg/kg). Conclusion: Treatment with methanolic extract of B. trifoliata is useful agent against the kidney stone formation.


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