scholarly journals Qualitative and quantitative estimation of comprehensive synaptic connectivity in short- and long-term cultured rat hippocampal neurons with new analytical methods inspired by Scatchard and Hill plots

2016 ◽  
Vol 471 (4) ◽  
pp. 486-491 ◽  
Author(s):  
Ryo Tanamoto ◽  
Yutaka Shindo ◽  
Mariko Niwano ◽  
Yoshinori Matsumoto ◽  
Norihisa Miki ◽  
...  
Author(s):  
Anuja Kolsure ◽  
Kratika Daniel ◽  
Mahesh Bhat

Budesonide is a potent glucocorticoid with a high local anti-inflammatory effect and low systemic bioavailability. The inhaled form is used in the long-term management of asthma and chronic obstructive pulmonary disease. Several analytical methods including UV, HPLC, LC-MS techniques has been developed for Budesonide alone and in combination with others. Methods indicating HPLC bioanalytical method, stability indicating HPLC method, ion pairing chromatographic method and chemometrics assisted HPLC methods are also described for Budesonide. For qualitative and quantitative estimation of Budesonide these analytical methods can be used. The following study describes reported analytical methods of Budesonide.


1981 ◽  
Vol 27 (4) ◽  
pp. 569-573 ◽  
Author(s):  
M D Shephard ◽  
L A Penberthy ◽  
C G Fraser

Abstract Intra-individual, interindividual, and analytical components of variation for each of 10 urine analytes were estimated from results obtained on analysis of urine specimens from 10 apparently healthy young men. In spot urines, urea and osmolality showed strong individuality, but intra-individual variances were larger than interindividual variances for sodium, urate, phosphate, and glucose. Urea and osmolality displayed strong individuality in daily urines, whereas sodium (when results were expressed in output terms), urate, potassium, and total protein (when results were expressed in concentration units) had intra-individual variances larger than interindividual variances. In monthly urines, calcium and glucose, in concentration terms, and phosphate, in output terms, exhibited strongest individuality. Analytical variance was a significant percentage of the total variance for total protein and glucose; the analytical methods we used for these analytes were probably unsatisfactory. A series of analytical goals for imprecision, based on biological variation, were derived. Although these goals may not be applicable in all clinical situations, they represent the beginning of a data base in the literature.


2020 ◽  
Vol 15 (1) ◽  
pp. 212-222
Author(s):  
Pratap Singh Awadhesh

AbstractThe purpose of this paper is to examine the role of key financial obligation factors on total factor productivity (TFP) for 34 Indian industries for the period 2008 2018 using qualitative and quantitative techniques. Financial obligations are measured by short- and long-term loans, operating expenses and liabilities. The outcome of qualitative techniques does not appear to support the hypothesis that short term and long-term loans, liabilities and operating expenses influence TFP. On the contrary, the evidences arise from quantitative technique appear to suggest that short term loan and operating expenses promote TFP. The study also suggests that complimentaries exist between operating expenses and short-term loan and they together appear to boost productivity.


2000 ◽  
Vol 23 (3) ◽  
pp. 94 ◽  
Author(s):  
Pam McGrath

There has been little analysis of the process of relocation for specialist treatment for patients with haematologicalmalignancies. Existing work does not cover the financial impact on families of such an experience. This paperdescribes seminal work in this area by presenting findings from research based on interviews with patients and familiesaffected by relocation. The two-fold intent informing this discussion is to provide data to initiate research in the area,whilst fostering a consideration of epistemological issues at the interface of qualitative and quantitative research. Theresults show that there are very significant financial problems. In planning psychosocial support for such families,serious consideration must be given to both their short and long-term economic plight.


Swiss Surgery ◽  
2001 ◽  
Vol 7 (1) ◽  
pp. 20-24 ◽  
Author(s):  
Robert ◽  
Mariéthoz ◽  
Pache ◽  
Bertin ◽  
Caulfield ◽  
...  

Objective: Approximately one out of five patients with Graves' disease (GD) undergoes a thyroidectomy after a mean period of 18 months of medical treatment. This retrospective and non-randomized study from a teaching hospital compares short- and long-term results of total (TT) and subtotal thyroidectomies (ST) for this disease. Methods: From 1987 to 1997, 94 patients were operated for GD. Thirty-three patients underwent a TT (mostly since 1993) and 61 a ST (keeping 4 to 8 grams of thyroid tissue - mean 6 g). All patients had received propylthiouracil and/or neo-mercazole and were in a euthyroid state at the time of surgery; they also took potassium iodide (lugol) for ten days before surgery. Results: There were no deaths. Transient hypocalcemia (< 3 months) occurred in 32 patients (15 TT and 17 ST) and persistent hypocalcemia in 8 having had TT. Two patients developed transient recurrent laryngeal nerve palsy after ST (< 3 months). After a median follow-up period of seven years (1-15) with five patients lost to follow-up, 41 patients having had a ST are in a hypothyroid state (73%), thirteen are euthyroid (23%), and two suffered recurrent hyperthyroidism, requiring completion of thyroidectomy. All 33 patients having had TT - with follow-ups averaging two years (0.5-8) - are receiving thyroxin substitution. Conclusions: There were no instances of persistent recurrent laryngeal nerve palsy in either group, but persistent hypoparathyroidism occurred more frequently after TT. Long after ST, hypothyroidism developed in nearly three of four cases, whereas euthyroidy was maintained in only one-fourth; recurrent hyperthyroidy was rare.


Author(s):  
Ian Neath ◽  
Jean Saint-Aubin ◽  
Tamra J. Bireta ◽  
Andrew J. Gabel ◽  
Chelsea G. Hudson ◽  
...  

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