Supercritical CO2 to recover extracts enriched in antioxidant compounds from beetroot aerial parts

2019 ◽  
Vol 19 ◽  
pp. 101169 ◽  
Author(s):  
Heloísa Fabian Battistella Lasta ◽  
Lucas Lentz ◽  
Natália Mezzomo ◽  
Sandra Regina Salvador Ferreira
Keyword(s):  
Supercritical Co2 ◽  
Antioxidant Compounds ◽  
Aerial Parts

scholarly journals Antioxidant Principles of Tanacetum vulgare L. Aerial Parts

2009 ◽  
Vol 4 (11) ◽  
pp. 1934578X0900401 ◽  
Author(s):  
Malindra Juan-Badaturuge ◽  
Solomon Habtemariam ◽  
Caroline Jackson ◽  
Michael JK Thomas
Keyword(s):  
Antioxidant Activity ◽  
Crude Extract ◽  
Radical Scavenging ◽  
Major Constituent ◽  
Antioxidant Compounds ◽  
Rheumatic Arthritis ◽  
Tanacetum Vulgare ◽  
Medicinal Uses ◽  
Inflammatory Conditions ◽  
Aerial Parts

The methanolic extract of aerial parts of Tanacetum vulgare L. (Asteraceae) and its fractions were investigated for antioxidant activity. The crude extract displayed DPPH radical scavenging effects with an EC50 value of 37 ± 1.2 μg/mL (n=3). Activity-guided fractionations of the crude extract resulted in the isolation of three antioxidant compounds; 3,5-O-dicaffeoylquinic acid (3,5-DCQA), axillarin and luteolin. 3,5-DCQA was the major constituent with antioxidant activity (IC50 = 9.7 μM) comparable with that of the standard quercetin (IC50 = 8.8 μM). Though the isolated compounds were previously known for their antioxidant effects, this is the first report on the identification of 3,5-DCQA from Tanacetum vulgare. The displayed potent antioxidant activity of the crude extract and isolated active principles is in support of the traditional medicinal uses of the plant for disease conditions such as wound healing, rheumatic arthritis and other inflammatory conditions.

Extraction of antioxidant compounds from blackberry (Rubus sp.) bagasse using supercritical CO2 assisted by ultrasound

2014 ◽  
Vol 94 ◽  
pp. 223-233 ◽  
Author(s):  
José Luis Pasquel Reátegui ◽  
Ana Paula da Fonseca Machado ◽  
Gerardo F. Barbero ◽  
Camila A. Rezende ◽  
Julian Martínez
Keyword(s):  
Supercritical Co2 ◽  
Antioxidant Compounds

scholarly journals Concentration of Antioxidant Compounds from Calendula officinalis through Sustainable Supercritical Technologies, and Computational Study of Their Permeability in Skin for Cosmetic Use

Antioxidants ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 96
Author(s):  
Raquel Mur ◽  
Elisa Langa ◽  
M. Rosa Pino-Otín ◽  
José S. Urieta ◽  
Ana M. Mainar
Keyword(s):  
Supercritical Co2 ◽  
Computational Study ◽  
Skin Permeability ◽  
Antioxidant Compounds ◽  
Calendula Officinalis ◽  
Permeability Model ◽  
Cosmetic Industry ◽  
Stratum Spinosum ◽  
Co2 Flow ◽  
Supercritical Technologies

The growing interest in the cosmetic industry in using compounds of natural and sustainable origin that are safe for humans is encouraging the development of processes that can satisfy these needs. Chlorogenic acid (CHA), caffeic acid (CAF) and ferulic acid (FA) are three compounds widely used within the cosmetic industry due to their functionalities as antioxidants, collagen modifiers or even as radiation protectors. In this work, two advanced separation techniques with supercritical CO2 are used to obtain these three compounds from Calendula officinalis, and these are then evaluated using a computational skin permeability model. This model is encompassed by the COSMO-RS model, the calculations of which make it possible to study the behaviour of the compounds in the epidermis. The results show that both CAF and FA are retained in the stratum corneum, while CHA manages to penetrate to the stratum spinosum. These compounds were concentrated by antisolvent fractionation with super-critical CO2 using a Response Surface Methodology to study the effect of pressure and CO2 flow rate. CHA, CAF and FA were completely retained in the precipitation vessel, with concentrations between 40% and 70% greater than in the original extract. The conditions predicted that the optimal overall yield and enrichment achieved would be 153 bar and 42 g/min.

scholarly journals Isolation of bioactive antioxidant compounds from the aerial parts of Allium roseum var. grandiflorum subvar. typicum Regel

2016 ◽  
Vol 4 (4) ◽  
pp. 305-309
Author(s):  
Lamia Sakka Rouis-Soussi ◽  
◽  
Asma El Ayeb ◽  
Saoussen Ben Salem ◽  
Hichem Ben Jannet ◽  
...  
Keyword(s):  
Antioxidant Compounds ◽  
Aerial Parts

scholarly journals Supercritical Antisolvent Fractionation of Antioxidant Compounds from Salvia officinalis

2021 ◽  
Vol 22 (17) ◽  
pp. 9351
Author(s):  
Raquel Mur ◽  
Juan I. Pardo ◽  
M. Rosa Pino-Otín ◽  
José S. Urieta ◽  
Ana M. Mainar
Keyword(s):  
Antioxidant Activity ◽  
Rosmarinic Acid ◽  
Supercritical Co2 ◽  
Qsar Model ◽  
Salvia Officinalis ◽  
Training Dataset ◽  
Antioxidant Compounds ◽  
Supercritical Antisolvent ◽  
Pure Compounds ◽  
Co2 Flow

The increasing interest towards greener antioxidants obtained via natural sources and more sustainable processes encourages the development of new theoretical and experimental methods in the field of those compounds. Two advanced separation methods using supercritical CO2 are applied to obtain valuable antioxidants from Salvia officinalis, and a first approximation to a QSAR model relating molecular structure with antioxidant activity is explored in order to be used, in the future, as a guide for the preselection of compounds of interest in these processes. Separation experiments through antisolvent fractionation with supercritical CO2 were designed using a Response Surface Methodology to study the effect of pressure and CO2 flow rate on both mass yields and capability to obtain fractions enriched in three antioxidant compounds: chlorogenic acid, caffeic acid and rosmarinic acid which were tracked using HPLC PDA. Rosmarinic acid was completely retained in the precipitation vessel while chlorogenic and caffeic acids, though distributed between the two separated fractions, had a major presence in the precipitation vessel too. The conditions predicted for an optimal overall yield and enrichment were 148 bar and 10 g/min. Although a training dataset including much more compounds than those now considered can be recommended, descriptors calculated from the σ-profiles provided by COSMO-RS model seem to be adequate for estimating the antioxidant activity of pure compounds through QSAR.

Chemical Composition and Antioxidant Activity of the Athamanta turbith ssp. haynaldii Volatiles

2018 ◽  
Vol 13 (6) ◽  
pp. 1934578X1801300
Author(s):  
Goran M. Petrović ◽  
Jelena G. Stamenković ◽  
Violeta D. Mitić ◽  
Gordana S. Stojanović ◽  
Bojan K. Zlatković ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Chemical Composition ◽  
Essential Oils ◽  
Antioxidant Compounds ◽  
Oil Composition ◽  
Headspace Volatiles ◽  
Aerial Parts ◽  
Germacrene D ◽  
Total Oil ◽  
Two Populations

The fresh aerial parts of essential oils and headspace volatiles of two populations of Athamanta turbith ssp. haynaldii were analyzed in detail by GC and GC/MS analyses. In headspace samples, 32 compounds were identified, representing 98.4% and 98.8% of the total volatiles and were dominated by hydrocarbon sesquiterpenes, representing over 60% of both. Germacrene D was the major component, followed by terpinolene and myristicin. The essential oils of A. turbith consisted mainly of phenylpropene compounds with myristicin being the major compound. Fifty two compounds were identified in the oil isolated from Perućac and 57 from Kremna, accounting for 99.0% and 99.6% of total detectable components, with myristicin (52.3% and 50.8%, respectively) being the major component. In both samples, myristicin, germacrene D and δ-cadinene make up over 78% of the total oil composition. Antioxidant activity was measured using four different assays: DPPH, ABTS, CUPRAC and TRP method. It was found that the essential oil showed low antioxidant capacities compared with standard antioxidant compounds.

Supercritical CO2 extraction of compounds from different aerial parts of Senecio brasiliensis: Mathematical modeling and effects of parameters on extract quality

2019 ◽  
Vol 153 ◽  
pp. 104589 ◽  
Author(s):  
Tássia C. Confortin ◽  
Izelmar Todero ◽  
Nicholas I. Canabarro ◽  
Luciana Luft ◽  
Gustavo A. Ugalde ◽  
...  
Keyword(s):  
Mathematical Modeling ◽  
Supercritical Co2 ◽  
Supercritical Co2 Extraction ◽  
Aerial Parts

Antioxidant compounds extracted from Diaporthe schini using supercritical CO2 plus cosolvent

2019 ◽  
Vol 43 (1) ◽  
pp. 133-141 ◽  
Author(s):  
Barbara Vargas da Rosa ◽  
Kátia Regina Kuhn ◽  
Gustavo Andrade Ugalde ◽  
Giovani Leone Zabot ◽  
Raquel Cristine Kuhn
Keyword(s):  
Supercritical Co2 ◽  
Antioxidant Compounds

scholarly journals Phytochemical analysis of volatiles and biological activities of Chaerophyllum bulbosum L. essential oils

2020 ◽  
pp. 80-80
Author(s):  
Jelena Stamenkovic ◽  
Aleksandra Djordjevic ◽  
Gordana Stojanovic ◽  
Violeta Mitic ◽  
Goran Petrovic
Keyword(s):  
Essential Oils ◽  
Biological Activities ◽  
Butylated Hydroxytoluene ◽  
Antioxidant Compounds ◽  
Phytochemical Analysis ◽  
Gram Positive Bacteria ◽  
Aerial Parts ◽  
Monoterpene Hydrocarbons ◽  
Main Class ◽  
Main Components

The present study reports for the first time the chemical composition of the headspace volatiles (HS) and essential oils obtained from fresh Chaerophyllum bulbosum roots and aerial parts, as well as biological activities of the essential oils. Generally, monoterpene hydrocarbons were found to be the main class of all investigated samples, with (E)-?-ocimene being the most abundant component. The results of antibacterial assay showed that both investigated samples exhibit bactericidal activity against two tested Gram-positive bacteria (Staphylococcus aureus and Bacillus subtilis subs. spizizeni) while they were inactive against tested Gram-negative bacteria (Escherichia coli and Salmonella abony). Regarding the antioxidant activity, it was found that the essential oils showed low antioxidant capacities in comparison with standard antioxidant compounds (such as butylated hydroxytoluene). The obtained results were expected given the fact that the main components in both samples were monoterpene hydrocarbons.

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