Protective role of Panax ginseng extract on lipid peroxidation and antioxidant status in polyethylene glycol induced Spathiphyllum leaves

2006 ◽  
Vol 32 (3) ◽  
pp. 143-148 ◽  
Author(s):  
Mohammad Babar Ali ◽  
Eun Joo Hahn ◽  
Kee-Yoeup Paek
2009 ◽  
Vol 30 (11) ◽  
pp. 1205-1214 ◽  
Author(s):  
Zafer Türkmen ◽  
Kültiğin Çavuşoğlu ◽  
Kürşat Çavuşoğlu ◽  
Kürşad Yapar ◽  
Emine Yalçin

2009 ◽  
Vol 81 (Suppl_1) ◽  
pp. 648-648
Author(s):  
Niraj R. Joshi ◽  
Sudip Banerjee ◽  
Raktim Mukherjee ◽  
Shail Chaube ◽  
A.V. Ramachandran

2007 ◽  
Vol 77 (1) ◽  
pp. 41-45 ◽  
Author(s):  
Chaturvedi ◽  
George ◽  
Machacha

The methanol extract of Raphanus sativus root extract showed a protective effect on paracetamol-induced hepatotoxicity in a dose-dependent manner. Degree of lipid peroxidation caused by paracetamol was measured in terms of thiobarbituric acid reactive substances (TBARS) and protection was measured in reference to serum glutamate oxaloacetate transaminase (SGOT), serum glutamate aspartate transaminase (SGPT), and blood and hepatic levels of antioxidants like glutathione and catalase. Administration of extract along with paracetamol showed significant protection. Levels of TBARS were found to be low, activities of SGOT and SGPT were low, while hepatic glutathione levels were significantly higher in experimental rats that received the mixture of paracetamol and the extract as compared to rats that received paracetamol only. Activities of catalase were also high in all experimental groups. Thus this study indicates the involvement of Raphanus sativus root extract with antioxidants like glutathione and catalase in rendering protection against paracetamol-induced lipid peroxidation and hepatotoxicity.


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