Design strategy of cell-penetrating copolymers for high efficient drug delivery

Biomaterials ◽  
2015 ◽  
Vol 52 ◽  
pp. 171-179 ◽  
Author(s):  
Ye Li ◽  
Diwen Feng ◽  
Xianren Zhang ◽  
Dapeng Cao
Keyword(s):  
Drug Delivery ◽  
Design Strategy ◽  
High Efficient ◽  
Cell Penetrating

Amoxicilin and Clavulanic Acid Intercaled Nanostructures for Dentistry Uses

2019 ◽  
Vol 56 (2) ◽  
pp. 396-398
Author(s):  
Georgeta Zegan ◽  
Daniela Anistoroaei ◽  
Elena Mihaela Carausu ◽  
Eduard Radu Cernei ◽  
loredana Golovcencu
Keyword(s):  
Drug Delivery ◽  
Clavulanic Acid ◽  
Bacterial Infections ◽  
Drug Delivery Systems ◽  
Intracellular Transport ◽  
Oral Treatment ◽  
Chitosan Nanoparticles ◽  
Well Being ◽  
Cell Penetrating ◽  
Novel Drug

Amoxicillin and clavulanic acid are two of the most commonly prescribed antibacterial worldwide for treating oral infectious diseases. Oral health is of big importance for well-being and general health. A few novel drug delivery systems were designed for oral treatment and prophylaxis of different diseases in the oral cavity. This work focused on the latest drug delivery development of the most common oral pathologies, namely, periodontitis, oral mucosal infections, dental caries and oral cancer. Herein we reveal the synthesis, characterization and application of chitosan nanoparticles for intracellular transport of the weakly cell-penetrating amoxicillin and clavulanic acid in order to improve their efficacy on bacterial infections.

siRNA versus pharmacological inhibition of endocytic pathways for studying cellular uptake of cell penetrating peptides and other drug delivery vectors

2010 ◽  
Vol 15 (23-24) ◽  
pp. 1103-1103
Author(s):  
Monerah H. Al-Soraj ◽  
Catherine L. Watkins ◽  
Dries Vercauteren ◽  
Stefaan De Smedt ◽  
Kevin Braeckmans ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cellular Uptake ◽  
Cell Penetrating Peptides ◽  
Pharmacological Inhibition ◽  
Cell Penetrating ◽  
Endocytic Pathways

Rapidly cell-penetrating and reductive milieu-responsive nanoaggregates assembled from an amphiphilic folate-camptothecin prodrug for enhanced drug delivery and controlled release

2017 ◽  
Vol 5 (3) ◽  
pp. 444-454 ◽  
Author(s):  
Zhigang Xu ◽  
Meili Hou ◽  
Xiaoxiao Shi ◽  
Yong-E. Gao ◽  
Peng Xue ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Folate Receptors ◽  
Tumour Detection ◽  
Cell Penetrating ◽  
Self Assembled

Self-assembled small molecular prodrug loaded with camptothecin in response to glutathione and folate receptors for combined tumour detection and treatment.

Cell‐Penetrating Peptides and Polymers for Improved Drug Delivery

ChemNanoMat ◽  
2020 ◽  
Vol 6 (8) ◽  
pp. 1138-1148
Author(s):  
Lin Gui ◽  
Xue‐Hao Zhang ◽  
Zeng‐Ying Qiao ◽  
Hao Wang
Keyword(s):  
Drug Delivery ◽  
Cell Penetrating Peptides ◽  
Cell Penetrating
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