scholarly journals Pyrazole ring-containing isolongifolanone derivatives as potential CDK2 inhibitors: Evaluation of anticancer activity and investigation of action mechanism

2021 ◽  
Vol 139 ◽  
pp. 111663
Author(s):  
Yunyun Wang ◽  
Wei Shi ◽  
Chenliang Wu ◽  
Lin Wan ◽  
Yuxun Zhao ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Pyrazole Ring ◽  
Action Mechanism

Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors

2017 ◽  
Vol 60 (17) ◽  
pp. 7569-7578 ◽  
Author(s):  
Hye-Kyung Park ◽  
Hanbin Jeong ◽  
Eunhwa Ko ◽  
Geumwoo Lee ◽  
Ji-Eun Lee ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Subcellular Distribution ◽  
Action Mechanism

Synthesis and Anticancer Activity of Some Fused Heterocyclic Compounds Containing Pyrazole Ring

2020 ◽  
Vol 40 (4) ◽  
pp. 1280-1290
Author(s):  
A. Y. Hassan ◽  
M. A. Mohamed ◽  
A. Abdel-Aziem ◽  
A. O. Hussain
Keyword(s):  
Anticancer Activity ◽  
Heterocyclic Compounds ◽  
Pyrazole Ring

Quantum-chemically-calculated mechanistically interpretable molecular descriptors for drug-action mechanism study – a case study of anthracycline anticancer antibiotics

RSC Advances ◽  
2016 ◽  
Vol 6 (78) ◽  
pp. 74426-74435 ◽  
Author(s):  
Siu-Kwong Pang
Keyword(s):  
Drug Development ◽  
Anticancer Activity ◽  
Molecular Descriptors ◽  
Drug Action ◽  
Mechanism Study ◽  
Action Mechanism ◽  
Action Mechanisms ◽  
Anticancer Antibiotics

Identification of drug-action mechanisms and understanding of chemical substituents affecting the anticancer activity of drugs are important for drug development.

Tribological Performance and Action Mechanism of Cadmium Dialkyldithiophosphate

2005 ◽  
Vol 48 (2) ◽  
pp. 171-175 ◽  
Author(s):  
Hu Jianqiang ◽  
Wei Xianyong ◽  
Yao Junbing ◽  
Xie Feng ◽  
Zhu Huanqin ◽  
...  
Keyword(s):  
Tribological Performance ◽  
Action Mechanism

Anticancer activity of resveratrol analogs from Eugenia rigida DC

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
MA Zaki ◽  
V Samoylenko ◽  
S Khan ◽  
RM Abd slam ◽  
MH Hetta ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Resveratrol Analogs

Specific inhbitor of ERK 1/2 AEZS-131: anticancer activity in models of human cancers with and without overactivation of ERK 1/2

2014 ◽  
Vol 74 (S 01) ◽  
Author(s):  
JB Engel ◽  
S Meyer ◽  
J Dietl ◽  
B Kwok ◽  
O Ortmann ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Human Cancers
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