scholarly journals Application of omics- and multi-omics-based techniques for natural product target discovery

2021 ◽  
Vol 141 ◽  
pp. 111833
Author(s):  
Hong-Wei Zhang ◽  
Chao Lv ◽  
Li-Jun Zhang ◽  
Xin Guo ◽  
Yi-Wen Shen ◽  
...  
Keyword(s):  
Natural Product ◽  
Target Discovery

Abstract NT-119: TARGET DISCOVERY OF NATURAL PRODUCT INSPIRED PHYLLANTHUSMINS FOR TREATMENT OF HIGH GRADE SEROUS OVARIAN CANCER

2019 ◽  
Author(s):  
Alexandria N. Young ◽  
Steven Kurina ◽  
Andrew Huntsman ◽  
Rathnayake A. Rathnayake ◽  
Melissa Korkmaz ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Natural Product ◽  
High Grade ◽  
Serous Ovarian Cancer ◽  
Target Discovery

Synthetic studies toward inducamide C

2021 ◽  
Author(s):  
Ardalan A. Nabi ◽  
Lydia M. Scott ◽  
Daniel P. Furkert ◽  
Jonathan Sperry
Keyword(s):  
Natural Product ◽  
Structural Revision ◽  
Synthetic Studies

The rare benzoxazepine ring in the alkaloid inducamide C is unstable and prone to rearrangement, indicating that structural revision of the natural product may be necessary.

Lessons learned from the optimization of natural product based kinase inhibitors through molecular calculations

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
V Myrianthopoulos ◽  
P Magiatis ◽  
AL Skaltsounis ◽  
L Meijer ◽  
E Mikros
Keyword(s):  
Natural Product ◽  
Kinase Inhibitors ◽  
Lessons Learned ◽  
Molecular Calculations
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