Neural Correlates of Emotion Regulation in Suicidal Ideation and Behavior in Schizophrenia: A Preliminary Study

2021 ◽  
Vol 89 (9) ◽  
pp. S268
Author(s):  
Matthew Hoptman ◽  
Danielle Rette ◽  
Molly Arnold ◽  
Constance Shope ◽  
Erin McDonald ◽  
...  
Author(s):  
Adam Bryant Miller ◽  
Katie A. McLaughlin ◽  
Daniel S. Busso ◽  
Stephanie Brueck ◽  
Matthew Peverill ◽  
...  

Crisis ◽  
2019 ◽  
Vol 40 (2) ◽  
pp. 134-140 ◽  
Author(s):  
Christopher R. DeCou ◽  
Stephanie P. Kaplan ◽  
Julie Spencer ◽  
Shannon M. Lynch

Abstract. Background and Aim: This study evaluated trauma-related shame as a mediator of the association between sexual assault severity and perceived burdensomeness and thwarted belongingness. Method: A total of 164 female undergraduates who reported attempted or completed sexual assault completed self-report measures of sexual assault, trauma-related shame, perceived burdensomeness, and thwarted belongingness. Results: Using path analysis, trauma-related shame mediated the association between sexual assault severity and perceived burdensomeness, and between sexual assault severity and thwarted belongingness. Limitations: The findings of this study are limited by the retrospective, self-report, and cross-sectional nature of these data, and do not allow for causal inference. Conclusion: Trauma-related shame warrants additional investigation as a mechanism that explains the association between sexual assault and psychosocial risk factors for suicidal ideation and behavior.


Author(s):  
Gemma T. Wallace ◽  
Anna R. Docherty

Psychosis spectrum disorders (PSDs) are complex, highly heritable psychiatric conditions with high economic and societal costs. PSDs have historically been conceptualized as neurocognitive disorders in which psychotic episodes and impairments in social and emotional functioning are attributed to deficits in neurocognition. Although cognitive pathways play an important role in the etiology and presentation of PSDs, recent research suggests that interrelations between cognition and emotion are highly relevant. Moreover, aberrant emotion regulation likely plays a significant role in the presentation of PSDs. Emotion dysregulation (ED) may underlie and exacerbate both negative and positive symptoms in PSDs, such as blunted affect, avolition, disorganized speech and behavior, poor social cognition, and delusions and hallucinations. Advances in measurement of emotion dysregulation—including self-reports, behavioral paradigms, neuroimaging paradigms, and neurophysiological assessment—have informed etiological models of emotion dysregulation in PSDs. This chapter reviews research on emotion regulation and dysregulation in PSDs. Notably, more severe presentations of emotion symptoms and greater emotion regulation impairments are associated with worse outcomes in PSDs. It may therefore be the case that focusing on ED as an early risk factor and intervention target could improve outcomes and prevention approaches for psychotic disorders.


Author(s):  
W. LaVome Robinson ◽  
Christopher R. Whipple ◽  
Leonard A. Jason ◽  
Caleb E. Flack

Author(s):  
Sian L. Ratcliffe ◽  
Phillip B. Chappell ◽  
Janel Boyce-Rustay ◽  
Svetlana Gloukhova ◽  
Denise M. Oleske

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Joseph M. Baker ◽  
Ning Liu ◽  
Xu Cui ◽  
Pascal Vrticka ◽  
Manish Saggar ◽  
...  

Abstract Researchers from multiple fields have sought to understand how sex moderates human social behavior. While over 50 years of research has revealed differences in cooperation behavior of males and females, the underlying neural correlates of these sex differences have not been explained. A missing and fundamental element of this puzzle is an understanding of how the sex composition of an interacting dyad influences the brain and behavior during cooperation. Using fNIRS-based hyperscanning in 111 same- and mixed-sex dyads, we identified significant behavioral and neural sex-related differences in association with a computer-based cooperation task. Dyads containing at least one male demonstrated significantly higher behavioral performance than female/female dyads. Individual males and females showed significant activation in the right frontopolar and right inferior prefrontal cortices, although this activation was greater in females compared to males. Female/female dyad’s exhibited significant inter-brain coherence within the right temporal cortex, while significant coherence in male/male dyads occurred in the right inferior prefrontal cortex. Significant coherence was not observed in mixed-sex dyads. Finally, for same-sex dyads only, task-related inter-brain coherence was positively correlated with cooperation task performance. Our results highlight multiple important and previously undetected influences of sex on concurrent neural and behavioral signatures of cooperation.


2021 ◽  
pp. 1-8
Author(s):  
Stephan Köhler ◽  
Veith Andreas Weilnhammer ◽  
Henrik Walter ◽  
Susanne Erk ◽  
Philipp Sterzer ◽  
...  

<b><i>Introduction:</i></b> Emotion regulation (ER), the ability to actively modulate one’s own emotion reactions, likely depends on the individual’s current emotional state. Here, we investigated whether negative emotions induced by an interpersonal autobiographic script affect the neuronal processes underlying ER. <b><i>Methods:</i></b> Twenty healthy participants were recruited and underwent functional magnetic resonance imaging (fMRI) during performance of distancing, a specific ER strategy, while viewing emotionally arousing pictures. Participants were instructed to either naturally experience (“permit” condition) or to actively downregulate (“regulate” condition) their emotional responses to the presented stimuli. Before each of the 4 runs in total, a neutral or negative autobiographical audio script was presented. The negative script comprised an emotionally negative event from childhood or adolescence that represented either emotional abuse or emotional neglect. The second event comprised an everyday neutral situation. We aimed at identifying the neural correlates of ER and their modulation by script-driven imagery. <b><i>Results:</i></b> fMRI analyses testing for greater responses in the “regulate” than the “permit” condition replicated previously reported neural correlates of ER in the right dorsolateral prefrontal cortex and the right inferior parietal lobule. A significant ER effect was also observed in the left orbitofrontal cortex. In the amygdala, we found greater responses in the “permit” compared to the “regulate” condition. We did not observe a significant modulation of the ER effects in any of these regions by the negative emotional state induced by autobiographical scripts. Bayesian statistics confirmed the absence of such modulations by providing marginal evidence for null effects. <b><i>Discussion:</i></b> While we replicated previously reported neural correlates of ER, we found no evidence for an effect of mood induction with individualized autobiographical scripts on the neural processes underlying ER in healthy participants.


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