Evaluating functional connectivity of executive control network and frontoparietal network in Alzheimer’s disease

AbstractThe purpose of the study was to investigate the executive control network function characteristics of interceptive and strategic sports athletes from open skill sports. In order to do so, we used a revised lateralized attention network task to measure executive control efficiency and activation related to flanker interference changes on the right frontoparietal network using functional near-infrared spectroscopy in athletes from different sport sub-categories. Strategic athletes had higher accuracy and lower flanker conflict effects on accuracy, as well as longer reaction time and stronger conflict effects under the valid cue and invalid cue conditions. This was accompanied by higher activity in the right inferior frontal gyrus. These results extend the evidence suggesting that differences among interceptive sports and strategic sports athletes are due to the former using higher velocities to solve conflicts, and the latter using higher accuracy in the same tasks. These effects are attributed to differences in the right frontoparietal network.

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Electroencephalography theta/beta ratio covaries with mind wandering and functional connectivity in the executive control network

Annals of the New York Academy of Sciences ◽

10.1111/nyas.14180 ◽

2019 ◽

Vol 1452 (1) ◽

pp. 52-64 ◽

Cited By ~ 5

Author(s):

Dana Son ◽

Mischa Rover ◽

Frances M. De Blasio ◽

Willem Does ◽

Robert J. Barry ◽

...

Keyword(s):

Functional Connectivity ◽

Executive Control ◽

Mind Wandering ◽

Control Network ◽

Executive Control Network

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Mindfulness Meditation Training and Executive Control Network Resting State Functional Connectivity

Psychosomatic Medicine ◽

10.1097/psy.0000000000000466 ◽

2017 ◽

Vol 79 (6) ◽

pp. 674-683 ◽

Cited By ~ 36

Author(s):

Adrienne A. Taren ◽

Peter J. Gianaros ◽

Carol M. Greco ◽

Emily K. Lindsay ◽

April Fairgrieve ◽

...

Keyword(s):

Functional Connectivity ◽

Executive Control ◽

Resting State ◽

Mindfulness Meditation ◽

Control Network ◽

Resting State Functional Connectivity ◽

Executive Control Network

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Reward and executive control network resting-state functional connectivity is associated with impulsivity during reward-based decision making for cocaine users

Drug and Alcohol Dependence ◽

10.1016/j.drugalcdep.2018.09.013 ◽

2019 ◽

Vol 194 ◽

pp. 32-39 ◽

Cited By ~ 11

Author(s):

Andréa L. Hobkirk ◽

Ryan P. Bell ◽

Amanda V. Utevsky ◽

Scott Huettel ◽

Christina S. Meade

Keyword(s):

Decision Making ◽

Functional Connectivity ◽

Executive Control ◽

Resting State ◽

Control Network ◽

Resting State Functional Connectivity ◽

Executive Control Network ◽

Cocaine Users

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Verbal working memory-related functional connectivity alterations in boys with attention-deficit/hyperactivity disorder and the effects of methylphenidate

Journal of Psychopharmacology ◽

10.1177/0269881117715607 ◽

2017 ◽

Vol 31 (8) ◽

pp. 1061-1069 ◽

Cited By ~ 4

Author(s):

Zhao-Min Wu ◽

Janita Bralten ◽

Li An ◽

Qing-Jiu Cao ◽

Xiao-Hua Cao ◽

...

Keyword(s):

Working Memory ◽

Single Dose ◽

Functional Connectivity ◽

Executive Control ◽

Verbal Working Memory ◽

Control Network ◽

Executive Control Network ◽

Hyperactivity Disorder ◽

Connectivity Patterns ◽

Behavioural Performance

Objective: Few studies have investigated verbal working memory-related functional connectivity patterns in participants with attention-deficit/hyperactivity disorder (ADHD). Thus, we aimed to compare working memory-related functional connectivity patterns in healthy children and those with ADHD, and study effects of methylphenidate (MPH). Method: Twenty-two boys with ADHD were scanned twice, under either MPH (single dose, 10 mg) or placebo, in a randomised, cross-over, counterbalanced placebo-controlled design. Thirty healthy boys were scanned once. We used fMRI during a numerical n-back task to examine functional connectivity patterns in case-control and MPH-placebo comparisons, using independent component analysis. Results: There was no significant difference in behavioural performance between children with ADHD, treated with MPH or placebo, and healthy controls. Compared with controls, participants with ADHD under placebo showed increased functional connectivity within fronto-parietal and auditory networks, and decreased functional connectivity within the executive control network. MPH normalized the altered functional connectivity pattern and significantly enhanced functional connectivity within the executive control network, though in non-overlapping areas. Conclusion: Our study contributes to the identification of the neural substrates of working memory. Single dose of MPH normalized the altered brain functional connectivity network, but had no enhancing effect on (non-impaired) behavioural performance.

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Effects of Mini-Basketball Training Program on Social Communication Impairment and Executive Control Network in Preschool Children with Autism Spectrum Disorder

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18105132 ◽

2021 ◽

Vol 18 (10) ◽

pp. 5132

Author(s):

Sixin Yang ◽

Zhimei Liu ◽

Xuan Xiong ◽

Kelong Cai ◽

Lina Zhu ◽

...

Keyword(s):

Preschool Children ◽

Functional Connectivity ◽

Executive Control ◽

Social Communication ◽

Children With Autism ◽

Autism Spectrum ◽

Control Group ◽

Control Network ◽

Executive Control Network ◽

Children With Asd

This study evaluated the effect of a 12-week mini-basketball training program (MBTP) on social communication (SC) and the executive control network (ECN) in preschool children with autism spectrum disorders (ASD). We finally assigned 30 preschool children with ASD to an experiment group (n = 15, 12 males, 3 females) or a control group (n = 15, 13 males, 2 females). The experiment group participated in a 12-week MBTP (40-min sessions per day, 5 days a week), while the control group only received the institutional routine behavioral rehabilitation intervention. The SC of preschool children with ASD was measured using the Social Responsiveness Scale, Second Edition (SRS-2), whereas functional connectivity (FC) of the ECN was assessed using resting-state functional magnetic resonance imaging (rs-fMRI) at pre-and post-test. Our results showed that SC exhibited significant improvement in the intervention group, especially in SRS-2 total score, social cognition, and social communication. We found significantly enhanced functional connectivity between the right cerebellum and left inferior frontal gyrus in the experimental group, while functional connectivity between the left middle temporal gyrus and right cerebellum were decreased in the control group. Furthermore, there were no significant correlations between the change in SC scores and FC of the ECN. Altogether, this study provides valuable insights that a 12-week MBTP improves SC and functional connectivity of the ECN in preschool children with ASD. We further inferred that neural mechanisms might be associated with changing the ECN of preschool ASD children caused by the 12-week MBTP.

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