The bio-chemically selective interaction of hydrogenated and oxidized ultra-small nanodiamonds with proteins and cells

The first few atomic layers of a solid can form a barrier between its interior and an often hostile environment. Although adsorption at the vacuum-solid interface has been studied in great detail, little is known about adsorption at the liquid-solid interface. Adsorption at a liquid-solid interface is of intrinsic interest, and is of technological importance because it provides a way to coat a surface with monolayer or multilayer structures. A pinhole free monolayer (with a reasonable dielectric constant) could lead to the development of nanoscale capacitors with unique characteristics and lithographic resists that surpass the resolution of their conventional counterparts. Chemically selective adsorption is of particular interest because it can be used to passivate a surface from external modification or change the wear and the lubrication properties of a surface to reflect new and useful properties. Immunochemical adsorption could be used to fabricate novel molecular electronic devices or to construct small, “smart”, unobtrusive sensors with the potential to detect a wide variety of preselected species at the molecular level. These might include a particular carcinogen in the environment, a specific type of explosive, a chemical agent, a virus, or even a tumor in the human body.

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Towards the use of chemically selective thin polymer films for TXRF analysis of Cr(III) and Cr(VI)

10.1021/scimeetings.0c06792 ◽

2020 ◽

Author(s):

Tate Brooke ◽

Royce Dansby-Sparks

Keyword(s):

Polymer Films ◽

Thin Polymer Films ◽

Thin Polymer ◽

Chemically Selective

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Fundamental Studies of Molecule-Surface Encounters Relevant to Molecular Adsorption, Size and Chemically Selective Collection, and Trace Identification/C and L (CBT)

10.21236/ada545390 ◽

2011 ◽

Author(s):

Steven J. Sibener

Keyword(s):

Molecular Adsorption ◽

Chemically Selective ◽

Selective Collection ◽

Molecule Surface

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Designing Chemically Selective Liquid Crystalline Materials that Respond to Oxidizing Gases

Journal of Materials Chemistry C ◽

10.1039/d1tc00544h ◽

2021 ◽

Author(s):

Nanqi Bao ◽

Jake Gold ◽

Tibor Szilvasi ◽

Huaizhe Yu ◽

Robert Twieg ◽

...

Keyword(s):

Computational Methods ◽

First Principles ◽

Liquid Crystalline ◽

Soft Materials ◽

Crystalline Materials ◽

Liquid Crystalline Materials ◽

Chemically Selective ◽

Kinetics Of

Computational methods can provide first-principles insights into the thermochemistry and kinetics of reactions at interfaces, but this capability has not been widely leveraged to design soft materials that respond selectively...

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Identification of domains that control the heteromeric assembly of Kir5.1/Kir4.0 potassium channels

AJP Cell Physiology ◽

10.1152/ajpcell.00479.2002 ◽

2003 ◽

Vol 284 (4) ◽

pp. C910-C917 ◽

Cited By ~ 24

Author(s):

Angelos-Aristeidis Konstas ◽

Christoph Korbmacher ◽

Stephen J. Tucker

Keyword(s):

Potassium Channels ◽

Potassium Channel ◽

Functional Diversity ◽

Kir Channels ◽

Selective Interaction ◽

Inwardly Rectifying ◽

In Cells ◽

Heteromeric Channels

Heteromultimerization between different inwardly rectifying (Kir) potassium channel subunits is an important mechanism for the generation of functional diversity. However, little is known about the mechanisms that control this process and that prevent promiscuous interactions in cells that express many different Kir subunits. In this study, we have examined the heteromeric assembly of Kir5.1 with other Kir subunits and have shown that this subunit exhibits a highly selective interaction with members of the Kir4.0 subfamily and does not physically associate with other Kir subunits such as Kir1.1, Kir2.1, and Kir6.2. Furthermore, we have identified regions within the Kir4.1 subunit that appear to govern the specificity of this interaction. These results help us to understand the mechanisms that control Kir subunit recognition and assembly and how cells can express many different Kir channels while maintaining distinct subpopulations of homo- and heteromeric channels within the cell.

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