Left Atrial Stiffness Index Independently Predicts Exercise Intolerance and Quality of Life in Older Patients with Obese HFpEF

The Glittre ADL-test (TGlittre) has been designed and validated to measure functional capacity during daily living activities in patients with chronic obstructive pulmonary disease (COPD) but is now used in several other situations. The aim of this study was to evaluate the applicability of TGlittre in a sample of overweight and obese eutrophic elderly. This was an experimental and cross-sectional study, which included 21 elderly women, allocated by BMI, in eutrophic (n = 8), overweight (n = 6) and obese (n = 7) groups. They were assessed for functional capacity (TGlittre and 6MWT), quality of life (QOL) with the questionnaire World Health Organization Quality of Life for Older People (WHOQOL-OLD) and handgrip strength (HGS). TGlittre correlated with age (p = 0.0040) and with 6MWT (p = 0.0086), but no statistical difference was found in TGlittre's performance time and the distance covered in 6MWT between groups. TGlittre did not correlate with HGS (p = 0.1493) and WHOQOL-Old (p = 0.0905). The data obtained in the present study corroborate that TGlittre is used as a functional measurement variable in the elderly population.Keywords: aged, obesity, exercise intolerance.

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Faculty Opinions recommendation of Effect of caloric restriction or aerobic exercise training on peak oxygen consumption and quality of life in obese older patients with heart failure with preserved ejection fraction: A randomized clinical trial.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726064910.793515585 ◽

2016 ◽

Author(s):

Jerome Fleg

Keyword(s):

Quality Of Life ◽

Heart Failure ◽

Clinical Trial ◽

Oxygen Consumption ◽

Older Patients ◽

Aerobic Exercise Training ◽

Peak Oxygen Consumption ◽

Preserved Ejection Fraction ◽

Patients With Heart Failure

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Efficacy of erlotinib and its effects on the quality of life of older patients with epidermal growth factor receptor‐mutant non‐small cell lung cancer: A prospective, multicenter, dose‐modification study

Geriatrics and Gerontology International ◽

10.1111/ggi.14243 ◽

2021 ◽

Author(s):

Yukari Tsubata ◽

Takeshi Masuda ◽

Kosuke Hamai ◽

Masaya Taniwaki ◽

Akari Tanino ◽

...

Keyword(s):

Quality Of Life ◽

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Older Patients ◽

Growth Factor Receptor ◽

Small Cell ◽

Small Cell Lung ◽

Epidermal Growth ◽

Receptor Mutant

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Does oral sodium bicarbonate therapy improve function and quality of life in older patients with chronic kidney disease and low-grade acidosis (the BiCARB trial)? Study protocol for a randomized controlled trial

Trials ◽

10.1186/s13063-015-0843-6 ◽

2015 ◽

Vol 16 (1) ◽

Cited By ~ 10

Author(s):

Miles D. Witham ◽

◽

Margaret M. Band ◽

Roberta C. Littleford ◽

Alison Avenell ◽

...

Keyword(s):

Quality Of Life ◽

Chronic Kidney Disease ◽

Randomized Controlled Trial ◽

Older Patients ◽

Controlled Trial ◽

Low Grade ◽

Randomized Controlled ◽

Bicarbonate Therapy ◽

Oral Sodium

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Regeneration of older patients after oncologic surgery. A temporal trajectory of geriatric assessment and quality of life parameters

Journal of Geriatric Oncology ◽

10.1016/j.jgo.2018.09.010 ◽

2019 ◽

Vol 10 (1) ◽

pp. 112-119 ◽

Cited By ~ 3

Author(s):

Barbara Deschler ◽

Gabriele Ihorst ◽

Michael Hüll ◽

Peter Baier

Keyword(s):

Quality Of Life ◽

Geriatric Assessment ◽

Older Patients ◽

Oncologic Surgery ◽

Temporal Trajectory

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Health-Related Quality of Life, Functional Decline, and Long-Term Mortality in Older Patients Following Hospitalisation Due to COVID-19

10.21203/rs.3.rs-150067/v1 ◽

2021 ◽

Author(s):

Marte Walle-Hansen ◽

Anette Ranhoff ◽

Marte Mellingsæter ◽

Marte Wang-Hansen ◽

Marius Myrstad

Keyword(s):

Quality Of Life ◽

Older Patients ◽

Functional Decline ◽

Health Related Quality ◽

Negative Change ◽

Related Quality ◽

Health Related

Abstract Background Older people are particularly vulnerable to severe COVID-19. Little is known about long-term consequences of COVID-19 on health-related quality of life and functional status in older people, and the impact of age in this context. We aimed to study age-related change in health-related quality of life (HR-QoL), functional decline and mortality among older patients six months following hospitalisation due to COVID-19. Methods This was a cohort study including patients aged 60 years and older admitted to four general hospitals in South-Eastern Norway due to COVID-19, from March 1 up until July 1, 2020. Patients who were still alive were invited to attend a six-month follow-up. Change in HR-QoL and functional status compared to before the COVID-19 hospitalisation were assessed using the EuroQol 5-dimensional-5 levels questionnaire (EQ 5D-5L). A change in visual analogue scale (VAS) score of 7 or more was considered clinically relevant. Results Out of 216 patients aged 60 years and older that were admitted to hospital due to COVID-19 during the study period, 171 were still alive 180 days after hospital admission, and 106 patients (62%) attended the six-month follow-up. Mean age was 74.3 years, 27 patients (26%) had experienced severe COVID-19. 57 participants (54%) reported a decrease in the EQ5D-5L VAS score after six months, with no significant difference between persons aged 75 years and older compared to younger. 70 participants (66%) reported a negative change in any of the dimensions of the EQ-5D-5L, with impaired ability to perform activities of daily life (35%), reduced mobility (33%) and having more pain or discomfort (33%) being the most commonly reported changes. 46 participants (43%) reported a negative change in cognitive function compared to before the COVID-19 hospitalisation. Six-month mortality was 21%, and increased with increasing age. Conclusions More than half of the patients reported a negative change in HR-QoL six months following hospitalisation due to COVID-19, and one out of three experienced a persistently impaired mobility and ability to carry out activities of daily living. The results suggest awareness of long-term functional decline in older COVID-19 patients.

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Kidney Transplant in an Old Woman-A Case Report and Review of the Literature

BANTAO Journal ◽

10.2478/bj-2014-0013 ◽

2015 ◽

Vol 12 (1) ◽

pp. 62-64

Author(s):

Lidija Orlic ◽

Ivana Mikolasevic ◽

Branka Sladoje-Martinovic ◽

Ivan Bubic and Sanjin Racki

Keyword(s):

Quality Of Life ◽

Renal Transplantation ◽

Elderly Patients ◽

End Stage Renal Disease ◽

Older Patients ◽

Review Of The Literature ◽

Stage Renal Disease ◽

End Stage ◽

Esrd Patients

Abstract The number of elderly patients with chronic kidney disease (CKD) as well as those with end-stage renal disease (ESRD) are increasing worldwide. Renal transplantation is now the treatment of choice for all ESRD patients, including those that are aged 65 or over. Namely, there is a growing evidence that elderly patients, in the absence of contraindications, have better outcomes after renal transplantation than alternative forms of RRT. Although survival, quality of life and economic advantages have been shown after transplantation, renal transplantation is still infrequently offered to older patients. Hereby, we present a case of an old woman who was transplanted in 1994 when “senior” program was still not established and when kidney transplantation at this age was rarity in many countries. She lived 16 years and 8 months with a well-functioning graft and died at the age of 89.

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