scholarly journals The potential of Ion Mobility Mass Spectrometry for high-throughput and high-resolution lipidomics

2018 ◽  
Vol 42 ◽  
pp. 42-50 ◽  
Author(s):  
Christine Hinz ◽  
Sonia Liggi ◽  
Julian L Griffin
The Analyst ◽  
2015 ◽  
Vol 140 (20) ◽  
pp. 6904-6911 ◽  
Author(s):  
M. Groessl ◽  
S. Graf ◽  
R. Knochenmuss

Separation and identification of isomeric species is a major challenge in lipidomics. Herein, we demonstrate that lipid isomers that differ only in position of the acyl chain, position of the double bond or double bond geometry can be distinguished using drift-tube ion mobility-mass spectrometry, even in complex biological samples.


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