Predictive capacity of a multimarker strategy to determine short-term mortality in patients attending a hospital emergency Department for acute heart failure. BIO-EAHFE study

Introduction: Angiopoietin-like protein 7 (ANGPTL7) is involved in extracellular matrix expression and inflammatory responses. However, the prognostic utility of ANGPTL7 among patients with acute heart failure (AHF) remains unclear. Objective: To evaluate the association between ANGPTL7 and short-term mortality due to AHF. Methods and Results: Patients with AHF were prospectively studied. Serum levels of ANGPTL7 were measured by an enzyme-linked immunosorbent assay. Associations between 30- and 90-day mortality and tertiles of ANGPTL7 were assessed by multivariate logistic regression models. The study comprised 142 patients. Median patient age was 68 years, and 69.7% were male. There were 20 deaths within 30 days and 37 deaths within 90 days. Crude rates of 30-day mortality in low, intermediate, and high tertiles of ANGPTL7 were 4.6, 14.6, and 22.9%, respectively. Crude rates of 90-day mortality of corresponding tertiles were 15.2, 25.0, and 37.5%. After adjusting for potential confounders, including NT-proBNP, the high tertile of ANGPTL7 was associated with a significantly increased risk of both 30-day mortality (odds ratio [OR]: 6.77, 95% confidence interval [CI]: 1.41–32.61, p = 0.017) and 90-day mortality (OR: 3.78, 95% CI: 1.38–10.36, p = 0.010) compared with the low tertile of ANGPTL7. Although mortality risk tended to be higher in the intermediate tertile than the low tertile, it did not reach statistical significance (OR: 3.75, 95% CI: 0.73–19.14, p = 0.113 for 30-day mortality; OR: 1.88, 95% CI: 0.66–5.34, p = 0.236 for 90-day mortality). Conclusions: Serum level of ANGPTL7 was independently associated with short-term mortality among patients with AHF.

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The rate of short-term revisits after diagnosis of non-specific abdominal pain is similar for surgeons and emergency physicians - results from a single tertiary hospital emergency department

Scandinavian Journal of Trauma Resuscitation and Emergency Medicine ◽

10.1186/s13049-020-00751-8 ◽

2020 ◽

Vol 28 (1) ◽

Author(s):

Leena Saaristo ◽

Mika T. Ukkonen ◽

Johanna M. Laukkarinen ◽

Satu-Liisa K. Pauniaho

Keyword(s):

Emergency Department ◽

Abdominal Pain ◽

Tertiary Hospital ◽

Hospital Emergency Department ◽

Emergency Physicians ◽

Hospital Emergency ◽

Short Term

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First episode of acute heart failure: Can we already predict the risk of short-term mortality?

European Journal of Internal Medicine ◽

10.1016/j.ejim.2020.04.041 ◽

2020 ◽

Vol 77 ◽

pp. 30-31

Author(s):

Pedro Moliner ◽

Josep Comin-Colet

Keyword(s):

Heart Failure ◽

Acute Heart Failure ◽

First Episode ◽

Short Term ◽

Short Term Mortality

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PROCALCITONIN AS PREDICTOR OF SHORT TERM MORTALITY IN PATIENT WITH ACUTE HEART FAILURE

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(14)60792-0 ◽

2014 ◽

Vol 63 (12) ◽

pp. A792 ◽

Cited By ~ 1

Author(s):

Sun Hee Park ◽

Dong Heon Yang ◽

Jang Hoon Lee ◽

Myung Hwan Bae ◽

Se Yong Jang ◽

...

Keyword(s):

Heart Failure ◽

Acute Heart Failure ◽

Short Term ◽

Short Term Mortality

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An Investigation of Risk Factors Affecting Short Term Mortality of Patients Referring to the Hospital Emergency Department

10.21203/rs.3.rs-108213/v1 ◽

2020 ◽

Author(s):

Elham Peyravi ◽

Hadid Hamrah ◽

Mohammad Sadegh Masoudi ◽

Milad Ahmadi Marzaleh ◽

Mahmoudreza Peyravi

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

Emergency Department ◽

Systolic Blood Pressure ◽

Fars Province ◽

Hospital Emergency ◽

Short Term ◽

Factors Affecting ◽

Emergency Department Overcrowding ◽

Short Term Mortality

Abstract Background and Objective: One of the causes of short-term mortality in patients is the lower quality of services provided by hospital emergency departments. Given the particular importance of the hospital emergency system and the presence of numerous problems, as well as short term mortality rates in hospitals, this study aimed to investigate the risk factors affecting short term mortality of patients presenting to the Emergency Department at Nemazi Hospital in Shiraz, Fars province in 2019.Methods: This is a retrospective study with a case control-analytical design. The sample size was 768 subjects. In the present study, the emergency department overcrowding was measured by the NEDOCS (National Emergency Department Overcrowding Scale) criterion. The severity of the disease was also evaluated based on the level of the triage of patients through the Emergency Severity Index (ESI) system and vital signs.Results: With each year increase in age, the chance of short-term mortality increases by 0.8%. People with O2 sat% <90% are 7.3 times more likely to experience short term mortality in an emergency department compared to people with O2 sat%> 90%. A significant relationship was noted between short term mortality and SBP (systolic blood pressure) in the hospital's emergency department. It was also found out that as the triage score increases, short term mortality decreases significantly. As hospital stay increases, the chance of the patients' mortality decreases by 0.5%.Conclusion: The percentage of arterial blood oxygen saturation, systolic blood pressure, respiration rate per minute, triage score, the way the patient arrives at the hospital, working shifts, hospitalization duration, age, and comorbidities were regarded as the risk factors for short term mortality. Therefore, promoting professional knowledge and skills of nurses and physicians in the hospitals' emergency department and up-to-dating and reviewing emergency protocols as well as similar research can greatly help reduce short term mortality in the hospital's emergency department.

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