scholarly journals Formation of size-tuneable biodegradable polymeric nanoparticles by solvent displacement method using micro-engineered membranes fabricated by laser drilling and electroforming

2016 ◽  
Vol 304 ◽  
pp. 703-713 ◽  
Author(s):  
Rahimah Othman ◽  
Goran T. Vladisavljević ◽  
Hamed Shahmohamadi ◽  
Zoltan K. Nagy ◽  
R.G. Holdich
2019 ◽  
Vol 3 (7) ◽  
pp. 1375-1384 ◽  
Author(s):  
Eshu Middha ◽  
Purnima Naresh Manghnani ◽  
Denise Zi Ling Ng ◽  
Huan Chen ◽  
Saif A. Khan ◽  
...  

We report a new enhanced solvent displacement method for the synthesis of highly monodisperse nanoparticles with direct visualization of the ouzo zone.


RSC Advances ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 2226-2234
Author(s):  
Ana María Pineda-Reyes ◽  
Mauricio Hernández Delgado ◽  
María de la Luz Zambrano-Zaragoza ◽  
Gerardo Leyva-Gómez ◽  
Nestor Mendoza-Muñoz ◽  
...  

A novel solvent emulsification-displacement method for obtaining polystyrene nanoparticles is reported. This process has an added value and can be an alternative for the recycling of expanded polystyrene.


2008 ◽  
Vol 22 (1) ◽  
pp. 12-17 ◽  
Author(s):  
Henelyta S. Ribeiro ◽  
Boon-Seang Chu ◽  
Sosaku Ichikawa ◽  
Mitsutoshi Nakajima

2001 ◽  
Vol 279 (8) ◽  
pp. 784-792 ◽  
Author(s):  
T. Trimaille ◽  
C. Chaix ◽  
T. Delair ◽  
C. Pichot ◽  
H. Teixeira ◽  
...  

2010 ◽  
Vol 37 (2) ◽  
pp. 160-166 ◽  
Author(s):  
Eddy Kei Noriega-Peláez ◽  
Néstor Mendoza-Muñoz ◽  
Adriana Ganem-Quintanar ◽  
David Quintanar-Guerrero

2022 ◽  
Vol 123 ◽  
pp. 107161
Author(s):  
Noamane Taarji ◽  
Meryem Bouhoute ◽  
Isao Kobayashi ◽  
Kenichi Tominaga ◽  
Hiroko Isoda ◽  
...  

2016 ◽  
Vol 194 ◽  
pp. 416-423 ◽  
Author(s):  
Tai Boon Tan ◽  
Nor Shariffa Yussof ◽  
Faridah Abas ◽  
Hamed Mirhosseini ◽  
Imededdine Arbi Nehdi ◽  
...  

Author(s):  
Zaida Urbán-Morlán

<p>Ethyl cellulose polymeric nanoparticles (NPs) were prepared using the solvent-displacement technique with ethanol as the solvent. Optimization of the method included evaluating stirring rate and stabilizer type. NPs of 142.1 to 226.5 nm were obtained in a reproducible and efficient way (95% process efficiency) and with good stability (at room temperature). Moreover, a recirculation device was used in order to obtain concentrated NPs dispersions by a continuous process with potential scale-up. This method was challenged to encapsulate a hydrophilic antiviral model molecule (glycyrrhizinic acid) resulting in low entrapment efficiencies (approximately 1%).</p><p> </p><p>The results indicate that NPs are obtained using this simple, economical process that offers the possibility to transport different agents for applications in food-processing, cosmetics production or pharmaceutical products.</p>


Author(s):  
Justine Wallyn ◽  
Thierry Vandamme ◽  
Nicolas Anton

Through this study, we propose to specifically focus on a particular stage of the fabrication of polymeric nanoparticles intended to be used as contrast agent for biomedical X-ray imaging. These nanoparticles, made from nanoprecipitation of preformed polymer, poly(MAOTIB) (poly(2-methacryloyloxyethyl(2,3,5-triiodobenzoate))) follow a solvent displacement process. This method, widely used in literature, is sensitive to the formulation and process parameters such as nature and concentrations of surfactant and polymer, solvent / non-solvent ratio, rate of addition of one phase in the other one, respective volumes of the phase, and homogenization shearing rate. On the other hand, in function of the aimed administration route, the final suspension should obey to specific constraints on final product, e.g. size range and polydispersity, final particle concentration (i.e. iodine concentration) and surfactant concentration. In the present work, we report a specific investigation on the nanoprecipiation of poly(MAOTIB) in tetrahydrofuran, dropped in water or ethanol (as non-solvent) and stabilized by nonionic surfactant. The objective is to show and explain the potentials and limitations of such the process, but also to provide a guidance on the way to optimize it.


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