Injectable Ag nanoclusters-based hydrogel for wound healing via eliminating bacterial infection and promoting tissue regeneration

2020 ◽  
pp. 127589
Author(s):  
Xiangyu Wang ◽  
Ziping Wang ◽  
Sha Fang ◽  
Yangzhe Hou ◽  
Xin Du ◽  
...  
Keyword(s):  
Wound Healing ◽  
Bacterial Infection ◽  
Tissue Regeneration ◽  
Ag Nanoclusters

scholarly journals β-Cyclodextrin/Triclosan Complex-Grafted Methacrylated Glycol Chitosan Hydorgel by Photocrosslinking via Visible Light Irradiation for a Tissue Bio-Adhesive

2021 ◽  
Vol 22 (2) ◽  
pp. 700
Author(s):  
Young Jae Moon ◽  
Sun-Jung Yoon ◽  
Jeung-Hyun Koo ◽  
Yihyun Yoon ◽  
Hye Jun Byun ◽  
...  
Keyword(s):  
Wound Healing ◽  
Bacterial Infection ◽  
Visible Light ◽  
Visible Light Irradiation ◽  
Light Irradiation ◽  
Tissue Adhesive ◽  
Proton Nuclear Magnetic Resonance ◽  
Scanning Calorimetry ◽  
Glycol Chitosan

Accelerating wound healing with minimized bacterial infection has become a topic of interest in the development of the new generation of tissue bio-adhesives. In this study, we fabricated a hydrogel system (MGC-g-CD-ic-TCS) consisting of triclosan (TCS)-complexed beta-cyclodextrin (β-CD)-conjugated methacrylated glycol chitosan (MGC) as an antibacterial tissue adhesive. Proton nuclear magnetic resonance (1H NMR) and differential scanning calorimetry (DSC) results showed the inclusion complex formation between MGC-g-CD and TCS. The increase of storage modulus (G’) of MGC-g-CD-ic-TCS after visible light irradiation for 200 s indicated its hydrogelation. The swollen hydrogel in aqueous solution resulted in two release behaviors of an initial burst and sustained release. Importantly, in vitro and in vivo results indicated that MGC-g-CD-ic-TCS inhibited bacterial infection and improved wound healing, suggesting its high potential application as an antibacterial tissue bio-adhesive.

scholarly journals Nanocomposite scaffolds for accelerating chronic wound healing by enhancing angiogenesis

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Hamed Nosrati ◽  
Reza Aramideh Khouy ◽  
Ali Nosrati ◽  
Mohammad Khodaei ◽  
Mehdi Banitalebi-Dehkordi ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Wound Healing ◽  
Tissue Regeneration ◽  
Molecular Mechanisms ◽  
Healing Process ◽  
The Body ◽  
Key Factors ◽  
Potential Applications ◽  
Nanocomposite Scaffolds

AbstractSkin is the body’s first barrier against external pathogens that maintains the homeostasis of the body. Any serious damage to the skin could have an impact on human health and quality of life. Tissue engineering aims to improve the quality of damaged tissue regeneration. One of the most effective treatments for skin tissue regeneration is to improve angiogenesis during the healing period. Over the last decade, there has been an impressive growth of new potential applications for nanobiomaterials in tissue engineering. Various approaches have been developed to improve the rate and quality of the healing process using angiogenic nanomaterials. In this review, we focused on molecular mechanisms and key factors in angiogenesis, the role of nanobiomaterials in angiogenesis, and scaffold-based tissue engineering approaches for accelerated wound healing based on improved angiogenesis.

Muscle-inspired MXene/PVA hydrogel with high toughness and photothermal therapy for promoting bacteria-infected wound healing

2022 ◽  
Author(s):  
Yan Li ◽  
Miao-miao Han ◽  
Yue Cai ◽  
Bing Jiang ◽  
Yuanxin Zhang ◽  
...  
Keyword(s):  
Wound Healing ◽  
Bacterial Infection ◽  
Human Health ◽  
Photothermal Therapy ◽  
Infected Wound ◽  
Traditional Therapy ◽  
High Toughness ◽  
Pva Hydrogel

The process of wound healing is often accompanied by bacterial infection, which is a serious threat to human health. The abuse of antibiotics in traditional therapy aggravates the resistance of...

Mapping the dominant wound healing and soft tissue regeneration QTL in MRL × CAST

2005 ◽  
Vol 16 (12) ◽  
pp. 918-924 ◽  
Author(s):  
Hongrun Yu ◽  
Subburaman Mohan ◽  
Godfred L. Masinde ◽  
David J. Baylink
Keyword(s):  
Wound Healing ◽  
Soft Tissue ◽  
Tissue Regeneration ◽  
Soft Tissue Regeneration

scholarly journals Platelet rich plasma in dermatology and cosmetology

2020 ◽  
Vol 6 (2) ◽  
pp. 288
Author(s):  
Shobhit Mohan ◽  
Lalit Mohan ◽  
Renu Sangal ◽  
Neelu Singh
Keyword(s):  
Wound Healing ◽  
Tissue Regeneration ◽  
Blood Product ◽  
Platelet Rich Plasma ◽  
Autologous Blood ◽  
Detailed Knowledge ◽  
Skin Rejuvenation ◽  
Scar Revision ◽  
Current Review

<p class="abstract">Platelet rich plasma (PRP) therapies in medicine has become increasing popular during the last decade. The interest in in the application of PRP in dermatology and cosmetology has increased recently in different applications such as alopecia, skin rejuvenation, wound healing, scar revision, and tissue regeneration. PRP is an autologous blood product obtained from the blood of the patients. The detailed knowledge about PRP should help clinicians better understand this therapy. In this view, the current review was done for a better understanding of what pathologies can be corrected with PRP.</p>

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