On the feasibility to conduct gradient liquid chromatography separations in narrow-bore columns at pressures up to 2000 bar

2016 ◽  
Vol 1473 ◽  
pp. 48-55 ◽  
Author(s):  
Ruben De Pauw ◽  
Tim Swier ◽  
Bart Degreef ◽  
Gert Desmet ◽  
Ken Broeckhoven
Keyword(s):  
Liquid Chromatography ◽  
Gradient Liquid Chromatography ◽  
Narrow Bore Columns

Analytical Solutions of the Ideal Model for Gradient Liquid Chromatography

2006 ◽  
Vol 78 (22) ◽  
pp. 7828-7840 ◽  
Author(s):  
Weiqiang Hao ◽  
Xiangmin Zhang ◽  
Keyong Hou
Keyword(s):  
Liquid Chromatography ◽  
Analytical Solutions ◽  
Ideal Model ◽  
Gradient Liquid Chromatography ◽  
The Ideal

Gradient liquid chromatography/mass spectrometry using microbore columns and a moving belt interface

1984 ◽  
Vol 56 (8) ◽  
pp. 1229-1236 ◽  
Author(s):  
M. J. Hayes ◽  
H. E. Schwartz ◽  
Paul. Vouros ◽  
B. L. Karger ◽  
A. D. Thruston ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Liquid Chromatography Mass Spectrometry ◽  
Chromatography Mass Spectrometry ◽  
Microbore Columns ◽  
Gradient Liquid Chromatography

scholarly journals Separation of Poly(styrene-block-t-butyl methacrylate) Copolymers by Various Liquid Chromatography Techniques

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Tina Šmigovec Ljubič ◽  
David Pahovnik ◽  
Majda Žigon ◽  
Ema Žagar
Keyword(s):  
Liquid Chromatography ◽  
Block Copolymers ◽  
Molar Mass ◽  
Small Difference ◽  
Reversed Phase ◽  
Butyl Methacrylate ◽  
Critical Conditions ◽  
Chromatographic Techniques ◽  
Methacrylate Copolymers ◽  
Gradient Liquid Chromatography

The separation of a mixture of three poly(styrene-block-t-butyl methacrylate) copolymers (PS-b-PtBMA), consisting of polystyrene (PS) blocks of similar length andt-butyl methacrylate (PtBMA) blocks of different lengths, was performed using various chromatographic techniques, that is, a gradient liquid chromatography on reversed-phase (C18 and C8) and normal-phase columns, a liquid chromatography under critical conditions for polystyrene as well as a fully automated two-dimensional liquid chromatography that separates block copolymers by chemical composition in the first dimension and by molar mass in the second dimension. The results show that a partial separation of the mixture of PS-b-PtBMA copolymers can be achieved only by gradient liquid chromatography on reversed-phase columns. The coelution of the two block copolymers is ascribed to a much shorter PtBMA block length, compared to the PS block, as well as a small difference in the length of the PtBMA block in two of these copolymers, which was confirmed by SEC-MALS and NMR spectroscopy.

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