CARDIOVASCULAR RISK FACTOR AWARENESS AND PREVALENCE AMONG CANADIAN MEN AND WOMEN - DOES GENDER PLAY A ROLE? A POPULATION BASED SURVEY ANALYSIS

2014 ◽  
Vol 30 (10) ◽  
pp. S86
Author(s):  
K.K. Quadros ◽  
E. Coomes ◽  
R.R. Bajaj ◽  
L.R. Finken ◽  
W. Sharieff ◽  
...  
Author(s):  
Anna Chu ◽  
Deirdre Hennessy ◽  
Sharon Johnston ◽  
Jacob Udell ◽  
Dennis Ko ◽  
...  

IntroductionOur increasing ability to link large population-based health administrative datasets to create ‘big data’ cohorts offers unique opportunities to conduct health and health services surveillance at lower costs than traditional methods using surveys or primary data collection. However, comparability of findings from big data with traditional methods is unknown. Objectives and ApproachIn the CArdiovascular HEalth in Ambulatory Care Research Team (CANHEART) ‘big data’ initiative, we linked 19 population-based health databases to obtain baseline and 5-year follow-up health information on a cohort of 9.8 million adult residents of Ontario, Canada as of January 2008. We compared cardiovascular risk factor prevalence with results from 3500 participants in the 2007-09 Canadian Health Measures Survey (CHMS), a traditional population health surveillance survey. Additionally, we determined cardiovascular preventative care use and clinical event rates by sex and age. Planned linkages to new data sources will enable continued cohort surveillance of population health-related and care indicators. ResultsCholesterol and glucose levels determined from the CANHEART cohort were comparable to the CHMS, whereas blood pressure values and obesity rates were substantially higher. Overall, receipt of cardiovascular preventive care in the CANHEART cohort was high, with 85.7% of males and 91.8% of females having blood pressure assessments, and 67.8% of males and 79.4% of females having weight assessments. Cholesterol and diabetes screening rates among those recommended for screening were over 75%. Incidence of myocardial infarction, stroke or cardiovascular death was 51% higher among males than females (3.8 and 2.5 events per 1000 person-years, respectively). Challenges encountered in analyzing data included treatment of repeated and time-varying measures, selection of valid diagnostic and physician billing codes, changing coding practices and handling of missing and outlying data. Conclusion/ImplicationsComparability of cardiovascular risk factor prevalence using linked administrative data with survey methods varies by indicator. Selection biases amongst survey participants and different measurement methods could explain discrepancies. The added ability to examine health care indicators longitudinally and by subgroup supports use of linked population-based data to enhance health surveillance.


2021 ◽  
Vol 331 ◽  
pp. e152-e153
Author(s):  
E. Rinkuniene ◽  
V. Dzenkeviciute ◽  
Z. Petrulioniene ◽  
E. Majauskienė ◽  
R. Puronaitė ◽  
...  

2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
M J Tilly ◽  
Z Lu ◽  
S Geurts ◽  
M A Ikram ◽  
M P M De Maat ◽  
...  

Abstract Background In a clinical setting, atrial fibrillation (AF) subgroups are defined, including paroxysmal, persistent, and permanent AF. These subgroups differ in terms of clinical characteristics, management strategy, and long-term outcomes. Application of clinical classifications in population-based settings is challenging as they are based on the duration of symptoms, recurrence, and treatment. Purpose We aim to develop an objective and standardized classification for AF patterns in the general population and examine the associated cardiovascular risk profiles and outcomes for the identified AF patterns. Methods Participants with only one reported AF episode were categorized as single-documented AF, if at least two separate AF episodes were reported as multiple-documented AF and as longstanding persistent AF if at least two consecutive ECG's at the research center showed AF, not followed by an ECG showing sinus rhythm. We fitted mixed effect models with age as time scale to characterize sex-specific cardiovascular risk factor trajectories preceding each AF pattern. We further used Cox proportional hazard modelling to describe the risk of coronary heart disease (CHD), heart failure (HF), stroke, and all-cause mortality following AF. Results We included 14,620 men and women aged ≥45 years. 1137 participants were categorized as single-documented AF, 208 as multiple-documented AF, and 57 as longstanding persistent AF. We identified significant differences in the preceding trajectories of weight, body mass index, systolic blood pressure, diastolic blood pressure, waist circumference, hip circumference, and waist-hip ratio with various AF patterns. In general, both men and women with persistent-elevated levels of these risk factors were prone to longstanding persistent AF. AF was associated with a large risk for subsequent CHD, HF, stroke, and mortality in the general population. Among the different AF patterns, single-documented AF conferred the largest risk of CHD [hazard ratio, 95% confidence interval: 1.92 (1.19–3.03)] and mortality [1.70 (1.41–2.07)] as compared to multiple-documented AF, and as compared to longstanding persistent AF [1.45 (0.72–2.90) and 3.66 (2.25–5.95), respectively]. Conclusion We developed a classification for AF patterns within a general population. We identified differences in risk factor trajectories preceding each AF pattern, which implies differences in pathophysiological mechanisms underlying AF. Participants with single-documented AF showed worse prognosis than those with multiple AF episodes. This might be due to the subgroup definition, since participants should live for a longer period of time to be categorized in the multiple-documented AF and longstanding persistent AF groups. This can also imply that participants suffering from multiple AF episodes are more frequently monitored, and treated for other risk factors. However, this could also suggest that singular AF episodes are not as innocent as commonly thought. FUNDunding Acknowledgement Type of funding sources: Public hospital(s). Main funding source(s): - Erasmus MC Mrace grant. - Netherlands Organization for the Health Research and Development (ZonMw) Figure 1 Figure 2. Progosis of various AF patterns


CHEST Journal ◽  
1991 ◽  
Vol 99 (2) ◽  
pp. 315-322 ◽  
Author(s):  
Millicent Higgins ◽  
Jacob B. Keller ◽  
Lynne E. Wagenknecht ◽  
Mary C. Townsend ◽  
David Sparrow ◽  
...  

2019 ◽  
Vol 26 (2_suppl) ◽  
pp. 25-32 ◽  
Author(s):  
Elisa Dal Canto ◽  
Antonio Ceriello ◽  
Lars Rydén ◽  
Marc Ferrini ◽  
Tina B Hansen ◽  
...  

The global prevalence of diabetes is predicted to increase dramatically in the coming decades as the population grows and ages, in parallel with the rising burden of overweight and obesity, in both developed and developing countries. Cardiovascular disease represents the principal cause of death and morbidity among people with diabetes, especially in those with type 2 diabetes mellitus. Adults with diabetes have 2–4 times increased cardiovascular risk compared with adults without diabetes, and the risk rises with worsening glycaemic control. Diabetes has been associated with 75% increase in mortality rate in adults, and cardiovascular disease accounts for a large part of the excess mortality. Diabetes-related macrovascular and microvascular complications, including coronary heart disease, cerebrovascular disease, heart failure, peripheral vascular disease, chronic renal disease, diabetic retinopathy and cardiovascular autonomic neuropathy are responsible for the impaired quality of life, disability and premature death associated with diabetes. Given the substantial clinical impact of diabetes as a cardiovascular risk factor, there has been a growing focus on diabetes-related complications. While some population-based studies suggest that the epidemiology of such complications is changing and that rates of all-cause and cardiovascular mortality among individuals with diabetes are decreasing in high-income countries, the economic and social burden of diabetes is expected to rise due to changing demographics and lifestyle especially in middle- and low-income countries. In this review we outline data from population-based studies on recent and long-term trends in diabetes-related complications.


Medicina ◽  
2012 ◽  
Vol 48 (6) ◽  
pp. 46 ◽  
Author(s):  
Andrejs Ērglis ◽  
Vilnis Dzērve ◽  
Jeļena Pahomova-Strautiņa ◽  
Inga Narbute ◽  
Sanda Jēgere ◽  
...  

Background and Objective. To date, the epidemiological studies of noncommunicable diseases in Latvia were more episodic and covered only selected areas. The first national crosssectional population-based survey of cardiovascular risk factors after regaining independence was carried out to provide reliable information on the cardiovascular risk factor profile in adults. Material and Methods. Computerized random sampling from the Registry of Latvian population was carried out. A total of 6000 enrolled subjects aged 25–74 years were divided into 10 age subgroups. The data of 3807 respondents (63.5% of all) were included into the final analysis. Results. The mean number of cardiovascular risk factors was 2.99±0.026 per subject: 3.45±0.043 and 2.72±0.030 for men and women, respectively. Of all the respondents, 75.2% had an increased total cholesterol level. Hypercholesterolemia was found in almost 56% of men and 41% of women in the age group of 25–34 years. Hyperglycemia was documented in 34.1% of the respondents (41.6% of men and 29.8% of women). More than two-thirds (67.8%) of the persons were overweight, while obesity was found in 25.6% of men and 32.6% of women. Arterial hypertension was identified in 44.8% of the respondents; its prevalence was higher in men than women (52.9% vs. 40.2%). There were more current smokers among men than women (30.5% vs. 11.4%). Conclusions. The levels of cardiovascular risk factors in Latvia were found to be relatively high. The data can be utilized as baseline characteristics that can be compared down the road including the monitoring of health prevention activities.


2020 ◽  
Author(s):  
Ravi Retnakaran ◽  
Baiju R Shah

<b>BACKGROUND:</b> Women who develop GDM have an elevated lifetime risk of cardiovascular disease, which has been attributed to an adverse cardiovascular risk factor profile that is apparent even within the first year postpartum. <a>Given its presence in the early postpartum, we hypothesized that this adverse cardiovascular risk factor profile may develop over time in the years prior to pregnancy. </a> <b><br> METHODS:</b> With population-based administrative databases, we identified all nulliparous women in Ontario, Canada, who had singleton pregnancies between January/2011 and December/2016 and ≥2 measurements of the following analytes between 2007 and the start of pregnancy: A1c, fasting glucose, random glucose, lipids, and transaminases. This population consisted of 8,047 women who developed GDM and 93,114 women who did not. <br> <b>RESULTS:</b> The two most recent pregravid tests were performed at median 0.61 years and 1.86 years before pregnancy, respectively. Women who went on to develop GDM had higher pregravid A1c, fasting glucose, random glucose, LDL-cholesterol, triglycerides, and ALT, and lower HDL-cholesterol, than their peers (all p<0.0001). Notably, in the years before pregnancy, women who went on to develop GDM had higher annual increases than their peers in A1c (1.9-fold higher) <a>(difference 0.0089%/year, 95%CI 0.0043 to 0.0135) </a>and random glucose (4.3-fold); greater annual decrease in HDL-cholesterol (5.5-fold); and lesser annual decline in LDL-cholesterol (0.4-fold)(all p≤0.0002). During this time, fasting glucose and triglycerides increased in women who developed GDM but decreased in their peers (both p<0.0001). <br> <b>CONCLUSION:</b> <a></a><a>The adverse cardiovascular risk factor profile of women with GDM evolves over time in the years before </a>pregnancy.


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