Effects of telephone lifestyle reinforcement and bariatric surgery on diet, hedonic hunger, and metabolic control in obese chinese patients with type 2 diabetes: a one-year prospective study

Abstract Background: There is abundant evidence reporting the relationship between triglycerides levels and type 2 diabetes mellitus, however few studies confirmed the influence of triglycerides levels on the incidence of diabetes. Bariatric surgery may lead to the remission of type 2 diabetes mellitus, but the effect of basal serum triglycerides levels on this reversal is unknown. This study aimed to assess the association between preoperative triglycerides levels and pre- and type 2 diabetes mellitus remission in obese patients one year after bariatric surgery. Methods: A retrospective study was conducted among 1959 obese patients who underwent bariatric surgery in our entre. Data on socio-demographic and clinical characteristics were used. Pre-diabetes and type 2 diabetes mellitus remission was defined as normal glycaemic measures at least one year’s duration without pharmacological therapy. Logistic regression models, crude and adjusted for sex, age, preoperative serum triglycerides levels and type of bariatric surgery, were used. Results: The median of preoperative serum triglycerides level was 121.00 (SD=75.00) mg/dL, and 34.7% and 30.0% of patients presented pre- and type 2 diabetes mellitus, respectively, at baseline. Preoperative serum triglycerides levels were higher in type 2 diabetes mellitus patients (139.00 vs. 106.00 mg/dL, in normal glycaemic patients; p<0.001) and showed to be significantly correlated with fasting glycaemia, glycated haemoglobin, homeostasis model assessment of insulin resistance and homeostasis model assessment of β-cell function. One year after bariatric surgery, 62.5% of patients with pre- or type 2 diabetes at baseline showed remission. Preoperative serum triglycerides levels were negatively associated with this remission (OR: 0.997; 95%CI=0.995–0.998), independently of, sex, age and type of bariatric surgery. Conclusions: One year after bariatric surgery, 62.5% of patients showed pre- or type 2 diabetes mellitus remission, being the preoperative serum triglycerides levels an important clinical parameter for remission. Keywords: triglycerides, diabetes, remission, obesity, bariatric surgery

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The Impact of Bariatric Surgery in the Epigenetics of Patients with Obesity and Type 2 Diabetes Mellitus: A Prospective Study of the DNA Methylation Remodeling in Adipose Tissue

Surgery for Obesity and Related Diseases ◽

10.1016/j.soard.2016.08.065 ◽

2016 ◽

Vol 12 (7) ◽

pp. S24-S25

Author(s):

Carlos Zerrweck ◽

Ernesto Sánchez ◽

Guillermo Martinez ◽

Paulina Baca ◽

Hernán Maydón ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Bariatric Surgery ◽

Dna Methylation ◽

Type 2 Diabetes Mellitus ◽

Adipose Tissue ◽

Prospective Study ◽

A Prospective Study ◽

The Impact

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COMPLICATIONS REQUIRING HOSPITAL MANAGEMENT AFTER BARIATRIC SURGERY

ABCD Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) ◽

10.1590/s0102-6720201500s100003 ◽

2015 ◽

Vol 28 (suppl 1) ◽

pp. 3-6 ◽

Cited By ~ 8

Author(s):

Aline WRZESINSKI ◽

Jéssica Moraes CORRÊA ◽

Tainiely Müller Barbosa FERNANDES ◽

Letícia Fernandes MONTEIRO ◽

Fabiana Schuelter TREVISOL ◽

...

Keyword(s):

Type 2 Diabetes ◽

Bariatric Surgery ◽

Postoperative Complications ◽

Hepatic Steatosis ◽

Standard Technique ◽

Female Gender ◽

First Year ◽

Frequent Complication ◽

One Year

Background: The actual gold standard technique for obesity treatment is the Roux-en-Y gastric bypass. However, complications may occur and the surgeon must be prepared for them. Aim: To evaluate retrospectively the complications occurrence and associated factors in patients who underwent bariatric surgery. Methods: In this study, 469 medical charts were considered, from patients and from data collected during outpatient consultations. The variables considered were gender, age, height, pre-operatory BMI, pre-operatory weight, pre-operatory comorbidities, time of hospital stay, postoperative complications that demanded re-admission to the hospital and the time elapsed between the procedure and the complication. The patients' follow up was, at least, one year. Results: The incidence of postoperative complications that demanded a hospital care was 24,09%. The main comorbidity presented in this sample was hepatic steatosis. The comorbidity that was associated with the postoperative period was type 2 diabetes. There was a tendency for the female gender be related to the complications. The cholecystectomy was the most frequent complication. Complications occurred during the first year in 57,35%. Conclusion: The most frequent complication was the need to perform a cholecystectomy, where the most frequent comorbidity was hepatic steatosis. Over half the complications occurred during the first year postoperatively. Type 2 diabetes was associated with the occurrence of postoperative complications; women had the highest incidence; body mass index was not associated with the occurrence of complications.

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