Evaluation of fatigue in patients with liver cirrhosis and chronic pancreatitis in a multicentre cross-sectional study

2020 ◽  
Vol 40 ◽  
pp. 515
Author(s):  
F. Meyer ◽  
K. Bannert ◽  
M. Wiese ◽  
S. Esau ◽  
L.F. Sautter ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Chronic Pancreatitis ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

Morphological and functional changes of chronic pancreatitis in patients with dyspepsia: A prospective, observational, cross-sectional study

Pancreatology ◽  
2018 ◽  
Vol 18 (3) ◽  
pp. 280-285 ◽  
Author(s):  
José Lariño-Noia ◽  
Daniel de la Iglesia ◽  
Julio Iglesias-García ◽  
Fernando Macías ◽  
Laura Nieto ◽  
...  
Keyword(s):  
Chronic Pancreatitis ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Functional Changes

scholarly journals Symptom, Adopting Healthy Life Style, and Quality of Life in Patients with Liver Cirrhosis: A Cross-Sectional Study

2020 ◽  
Author(s):  
Myung Kyung Lee ◽  
Woo Jin CHUNG
Keyword(s):  
Quality Of Life ◽  
Liver Cirrhosis ◽  
Fruits And Vegetables ◽  
Short Form ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Quadrant Pain ◽  
Cross Sectional ◽  
Intensity Of Exercise

Abstract Background: Previous studies have not considered a broad range of symptoms and the association with healthy behavior and quality of life of patients with liver cirrhosis. Objectives: The purposes of the study were to examine the association of symptom with adopting exercise and consuming fruits and vegetables, and to identify factors associated with quality of life in patients with liver cirrhosis.Methods: This cross-sectional study enrolled 91 consecutive patients with liver cirrhosis in one tertiary general hospital in South Korea between February 2016 and January 2017. Each study participant completed a self-administered questionnaire that measured symptom, stage-of-change in performing exercise and consumption of fruits and vegetables, and the Korean version of the 36-item Short-Form Health Survey. Multivariate logistic regression analysis and multiple regression models was used respectively to examine the association of each symptom with engaging in exercise and increasing consumption of fruits and vegetables and to evaluate factors affecting quality of life.Results: Experiencing nausea was associated with increased intensity of exercise but experiencing shortness of breath was associated with decreased intensity of exercise. Experiencing right upper quadrant pain was associated with increased consumption of fruits and vegetables and muscle cramps, anorexia, right upper quadrant pain and body pain, itching, ascites or edema, bruising, and change in appearance negatively affected quality of life.Conclusions: The results suggest that the types of symptoms experienced by a patient with liver cirrhosis hinder or promote the patient’s adoption of exercise and dietary behavior. Experiencing symptoms may negatively affect quality of life. Caregivers should provide supportive care to patients with liver cirrhosis, which includes assessing and managing symptoms to improve quality of life.

scholarly journals Left Atrial Function by Speckle Tracking in Liver Cirrhosis. A Cross-sectional Study

2019 ◽  
Vol 87 (6) ◽  
pp. 453-456
Author(s):  
Zuilma Vásquez Ortiz ◽  
Verónica Rendón Bravo ◽  
Pablo Reyes Hernández ◽  
Jorge Osequera Moguel
Keyword(s):  
Liver Cirrhosis ◽  
Left Atrial ◽  
Speckle Tracking ◽  
Cross Sectional Study ◽  
Atrial Function ◽  
Left Atrial Function ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals SPONTANEOUS BACTERIAL PERITONITIS

2018 ◽  
Vol 25 (02) ◽  
pp. 302-306
Author(s):  
Noor Gul ◽  
Tahir Habib Rizvi ◽  
Memoona Alam
Keyword(s):  
Liver Cirrhosis ◽  
Frequency Distribution ◽  
Spontaneous Bacterial Peritonitis ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Bacterial Peritonitis ◽  
Medical Wards ◽  
Study Setting

Objectives: To record frequency of spontaneous bacterial peritonitis in patientsof liver cirrhosis with low ascitic protein contents. Methodology: This study included 81 patientswith liver cirrhosis with low ascitic proteins level. All the patients were evaluated for the presenceof spontaneous bacterial peritonitis which was described as frequency distribution table. StudyDesign: Cross Sectional Study. Setting: Medical wards of DHQ and Allied Hospitals (PunjabMedical College) Faisalabad. Duration of Study: 11th May 2011 to 10th November 2011.Results: Spontaneous bacterial peritonitis was present among 29 (35.8%) patients and wasnot present among 52 (64.2%) patients. Conclusion: All the patients with low ascitic proteinlevel should be evaluated for the presence of spontaneous bacterial peritonitis and antibioticprophylaxis should be considered.

Association between Pancreatic Burnout and Liver Cirrhosis in Alcoholic Chronic Pancreatitis

Digestion ◽  
2021 ◽  
pp. 1-8
Author(s):  
Michael Hirth ◽  
Philipp Göltl ◽  
Christel Weiss ◽  
Matthias P. Ebert ◽  
Alexander Schneider
Keyword(s):  
Liver Cirrhosis ◽  
Chronic Pancreatitis ◽  
Alcohol Consumption ◽  
Disease Duration ◽  
Close Association ◽  
Liver Stiffness ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Endocrine Insufficiency ◽  
Cross Sectional Imaging

<b><i>Background/Objectives:</i></b> In chronic pancreatitis (CP), progressive fibrosis of the pancreas leads to exocrine and endocrine insufficiency and, finally, to pancreatic burnout. Alcohol consumption is associated with fibrosis in the pancreas and the liver, and the activation of stellate cells plays a central role in the induction of fibrosis in both organs. However, the relationship between pancreatic burnout and liver cirrhosis (LC) is still poorly understood in patients with alcoholic CP (ACP). <b><i>Methods:</i></b> We performed a single-center, retrospective, cross-sectional study with 537 CP patients. We analyzed the clinical presence of early and advanced pancreatic burnout and stated LC in cases of typical alterations in histology, liver stiffness measurement, cross-sectional imaging, or ultrasound. We analyzed further clinical parameters. <b><i>Results:</i></b> The frequency of advanced pancreatic burnout was 6.5% for ACP (20/306) and 4% for non-ACP (8/206; <i>p</i> = 0.20; χ<sup>2</sup> test). Advanced pancreatic burnout was not associated with the amount of alcohol consumption (<i>p</i> = 0.34) but with the disease duration (<i>p</i> = 0.0470) and rate of calcification (<i>p</i> = 0.0056). Furthermore, advanced pancreatic burnout was associated with LC (<i>p</i> &#x3c; 0.0001) but cannot be explained by the amount of alcohol consumption. In ACP with alcohol consumption &#x3e;80 g/day, an isolated LC was significantly more frequently detectable (14%, without pancreatic burnout) than an isolated advanced pancreatic burnout (1%, without LC). These results were confirmed by multivariable analyses. <b><i>Conclusions:</i></b> We identified a close association between LC and pancreatic burnout. The disease duration positively correlates with the development of pancreatic burnout. The liver seems to be more vulnerable to alcohol than the pancreas.

scholarly journals Association between serum irisin concentrations and sarcopenia in patients with liver cirrhosis: a cross-sectional study

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Mingyuan Zhao ◽  
Xiaoshuang Zhou ◽  
Chengying Yuan ◽  
Rongshan Li ◽  
Yuehong Ma ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Lumbar Vertebra ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Skeletal Muscle Index ◽  
Multivariable Regression ◽  
Cirrhotic Patients

Abstract Sarcopenia is an independent predictor of mortality in patients with liver cirrhosis. However, evidence has emerged that skeletal muscles mediate their protective effect against sarcopenia by secreting myokines. Therefore, we investigated whether irisin was associated with sarcopenia in patients with liver cirrhosis. This was an observational cross-sectional study of data collected from 187 cirrhotic patients. Sarcopenia was defined by computed tomography (CT) scans using specific cutoffs of the 3rd lumbar vertebra skeletal muscle index (L3 SMI). Morning irisin levels were obtained in all patients. Of the 187 patients, sarcopenia was noted in 73 (39%). Irisin concentrations were lower in sarcopenic patients (32.40 pg/ml [interquartile range (IQR): 18.70, 121.26], p < 0.001) than in nonsarcopenic patients. There was a weak correlation between L3 SMI and irisin levels (r = 0.516, p < 0.001). Multivariable regression analysis including L3 SMI, body mass index (BMI), very-low-density lipoprotein (VLDL)-cholesterol, aspartate aminotransferase (AST), adiponectin, and irisin levels showed that L3 SMI (odds ratio [OR] = 0.915, p = 0.023), adiponectin levels (OR = 1.074, p = 0.014), irisin levels (OR = 0.993, p < 0.001) and BMI (OR = 0.456, p = 0.004) were independently associated with sarcopenia. Irisin levels are associated with sarcopenia in patients with liver cirrhosis. This paper addresses a gap in the literature and facilitates the future transition into clinical treatment.

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