Vector analysis of classical (BIVAc) and specific (BIVAe) bioelectrical impedance in patients with chronic kidney disease (CKD)

2021 ◽  
Vol 46 ◽  
pp. S686
Author(s):  
N.E.X.M. Gonçalves ◽  
P.G. Chiarello
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Bioelectrical Impedance ◽  
Vector Analysis

scholarly journals P0921ROLE OF UREMIC TOXIN, INDOXYL SULFATE IN SARCOPENIA OF NONDIALYSIS DEPENDENT-CHRONIC KIDNEY DISEASE PATIENTS

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Jun Chul Kim ◽  
Seok Hui Kang ◽  
Miyeun Han ◽  
Su-Hyun Kim ◽  
Ran-Hui Cha ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Muscle Mass ◽  
Bioelectrical Impedance ◽  
Impedance Analysis ◽  
Indoxyl Sulfate ◽  
High Rate ◽  
Uremic Toxin ◽  
Inverse Association

Abstract Background and Aims Sarcopenia in patients with chronic kidney disease (CKD) is highly prevalent and leads to high rate of morbidity and mortality. The role of indoxyl sulfate (IS) to develop muscle wasting has been researched and proved in several animal model studies. However, there is no human data showing this relationship in CKD population. The aim of the present study was to evaluate the association between serum IS levels and each component of sarcopenia in nondialysis dependent-CKD (NDD-CKD) patients. Method We enrolled 150 NDD-CKD adult patients from 6 medical centers and collected data of demographics, blood chemistry such as indoxyl sulfate, interleukin (IL)-6, and estimated glomerular filtration rate using MDRD equation (eGFR), and body mass index (BMI, kg/m2). We also measured hand-grip strength (HGS, kg), walking speed (WS, m/s), skeletal muscle mass (SMM, kg) by bioelectrical impedance analysis (BIA). Results The numbers of male sex was 97 (64.7%). Mean age was 63.7±10.8 years old. The numbers of patients with diabetes mellitus was 77 (52.0%). Charlson comorbidity index (CCI) score was 3.9 ± 1.9. The stage of CKD ranged from 3 to 5 (eGFR=33.7±12.0 ml/min/1.73m2, mean±SD). Correlation coefficients with indoxyl sulfate levels were 0.211 for serum IL-6 level (P = 0.010), -0.212 for HGS (P = 0.009), -0.188 for WS (P = 0.021), -0.237 for SMM (P = 0.004), and -0.168 for BMI (P = 0.041), respectively. Correlation analysis showed that indoxyl sulfate levels had inverse association significantly with HGS, WS, SMM, and BMI and were positively associated with serum IL-6 levels. Conclusion Our study shows that higher serum indoxyl sulfate level was significantly associated with lower levels of muscle mass, strength, and physical performance function and higher inflammation status in non-dialysis dependent CKD patients. We suggest that the role of AST120 in prevention or treatment of sarcopenia be studied in this CKD population.

scholarly journals Estimation of body composition and water data depends on the bioelectrical impedance device

2018 ◽  
Vol 9 (1) ◽  
pp. 96-105 ◽  
Author(s):  
Natália T. Bellafronte ◽  
Marina R. Batistuti ◽  
Nathália Z. dos Santos ◽  
Héric Holland ◽  
Elen A. Romão ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Chronic Kidney Disease ◽  
Body Composition ◽  
Kidney Disease ◽  
Impedance Spectroscopy ◽  
Body Mass ◽  
Intraclass Correlation ◽  
Bioelectrical Impedance ◽  
Pearson’S Correlation ◽  
Pearson's Correlation

Abstract Overweight, obese and chronic kidney disease patients have an altered and negative body composition being its assessment important. Bioelectrical impedance analysis is an easy-to-operate and low-cost method for this purpose. This study aimed to compare and correlate data from single- and multi-frequency bioelectrical impedance spectroscopy applied in subjects with different body sizes, adiposity, and hydration status. It was a cross-sectional study with 386 non-chronic kidney disease volunteers (body mass index from 17 to 40 kg/m2), 30 patients in peritoneal dialysis, and 95 in hemodialysis. Bioelectrical impedance, body composition, and body water data were assessed with single- and multi-frequency bioelectrical impedance spectroscopy. Differences (95% confidence interval) and agreements (Bland-Atman analyze) between devices were evaluated. The intraclass correlation coefficient was used to measure the strength of agreement and Pearson’s correlation to measure the association. Regression analyze was performed to test the association between device difference with body mass index and overhydration. The limits of agreement between devices were very large. Fat mass showed the greatest difference and the lowest intraclass and Pearson’s correlation coefficients. Pearson’s correlation varied from moderate to strong and the intraclass correlation coefficient from weak to substantial. The difference between devices were greater as body mass index increased and was worse in the extremes of water imbalance. In conclusion, data obtained with single- and multi-frequency bioelectrical impedance spectroscopy were highly correlated with poor agreement; the devices cannot be used interchangeably and the agreement between the devices was worse as body mass index and fat mass increased and in the extremes of overhydration.

scholarly journals Prevalence of sarcopenia in community-dwelling older adults using the updated EWGSOP2 definition according to kidney function and albuminuria

2020 ◽  
Vol 20 (S1) ◽  
Author(s):  
Rafael Moreno-Gonzalez ◽  
◽  
Xavier Corbella ◽  
Francesco Mattace-Raso ◽  
Lisanne Tap ◽  
...  
Keyword(s):  
Older Adults ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Kidney Function ◽  
Handgrip Strength ◽  
Bioelectrical Impedance ◽  
Community Dwelling ◽  
Cross Sectional ◽  
European Working ◽  
Community Dwelling Older Adults

Abstract Background Loss of muscle mass and function may be more pronounced in older adults with chronic kidney disease (CKD) and with albuminuria. Thus, we investigated the prevalence of sarcopenia among community-dwelling older adults according to kidney function and grade of albuminuria. We also explored differences in the prevalence of sarcopenia according to three different equations for the estimation of glomerular filtration rate (eGFR). Methods A cross-sectional analysis of 1420 community-dwelling older adults (≥75 years old) included in the SCOPE study, a multicenter prospective cohort study, was conducted. Comprehensive geriatric assessment including short physical performance battery (SPPB), handgrip strength test and bioelectrical impedance analysis (BIA) was performed. Sarcopenia was defined using the updated criteria of the European Working Group on Sarcopenia in Older People (EWGSOP2). eGFR was calculated using Berlin Initiative Study (BIS), Chronic Kidney Disease Epidemiological Collaboration (CKD-EPI) and Full Age Spectrum (FAS) equations, and urinary albumin-to-creatinine ratio (ACR) was collected to categorize CKD according to Kidney Disease Improving Global Outcomes guidelines. Results Median age was 79.5 years (77.0–83.0), 804 (56.6%) were women. Using EWGSOP2 definition, 150 (10.6%) participants met diagnostic criteria for sarcopenia. Moreover, 85 (6%) participants had severe sarcopenia. Sarcopenia was more prevalent in participants with more advanced stages of CKD according to BIS eq. (9.6% in stages 1 and 2 and 13.9% in stages 3a, 3b and 4, p = 0.042), and also according to CKD-EPI (9.8% vs. 14.2%, p = 0.042) and FAS although not reaching statistical signification (9.8% vs. 12.7%, p = 0.119). Thus, differences in prevalence are observed among CKD categories as estimated by different equations. Prevalence of sarcopenia was also higher with increasing albuminuria categories: 9.3% in normoalbuminuric, 13.2% in microalbuminuric and 16.8% in macroalbuminuric participants, (p = 0.019). Conclusions Sarcopenia is common among community-dwelling older adults, especially among those with more advanced CKD categories, with prevalence estimates differing slightly depending on the equation used for the estimation of eGFR; as well as among those with higher albuminuria categories.

Agreement Between Anthropometry and Bioelectrical Impedance for Measuring Body Fat in Nonobese and Obese Nondialyzed Chronic Kidney Disease Patients

2008 ◽  
Vol 18 (4) ◽  
pp. 355-362 ◽  
Author(s):  
Maria Inês Barreto Silva ◽  
Carla Maria Avesani ◽  
Barbara Vale ◽  
Carla Lemos ◽  
Rachel Bregman
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Body Fat ◽  
Bioelectrical Impedance

scholarly journals Evaluation of volume distribution in chronic kidney disease children with bioelectrical impedance analysis

2016 ◽  
Vol 9 (3) ◽  
pp. 196-202
Author(s):  
Dilek Yılmaz ◽  
Ferah Sönmez ◽  
Sacide Karakaş ◽  
Önder Yavaşcan ◽  
Nejat Aksu ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Bioelectrical Impedance Analysis ◽  
Bioelectrical Impedance ◽  
Impedance Analysis ◽  
Volume Distribution

scholarly journals Relation between Serum Intact Parathyroid Hormone Level and Hematocrit in Chronic Kidney Disease Patients

2017 ◽  
Vol 13 (3) ◽  
pp. 220-223
Author(s):  
L.P. Adhikary ◽  
A. Pokhrel ◽  
S.K. Yadava ◽  
D. Khadka ◽  
R. Thakur
Keyword(s):  
Chronic Kidney Disease ◽  
Parathyroid Hormone ◽  
Kidney Disease ◽  
Disease Patient ◽  
Bioelectrical Impedance ◽  
Impedance Method ◽  
Reverse Correlation ◽  
Intact Parathyroid Hormone ◽  
Hematocrit Level ◽  
Immuno Assay

Background Anemia is a common complication of chronic kidney disease. There are various causes of anemia in chronic kidney disease patients on hemodialysis. Secondary hyperparathyroidism is one of the less recognized causes of anemia in chronic kidney disease patients.Objectives The main objective of the study is to find the correlation between intact parathyroid hormone and hematocrit level in chronic kidney disease (CKD) patients undergoing hemodialysis.Method Verbal consent was taken from all the participants. Eighty participants between the age of 29 and 70 years with chronic kidney disease having indication of hemodialysis were included in this study. Hematocrit was measured by bioelectrical impedance method and serum intact parathyroid hormone was by using Chemi Luminescence Immuno Assay (CLIA) method.Result A weak reverse correlation was found between serum intact parathyroid level and hematocrit (r= -0.33).Conclusion In chronic kidney disease patient, there is reverse correlation between level of serum intact parathyroid and hematocrit level. This association may have clinical relevance in assessing the cause of unexplained low hemoglobin level in CKD patients.

Sign in / Sign up

Export Citation Format

Share Document