scholarly journals Development and validation of a prediction model for severe respiratory failure in hospitalized patients with SARS-CoV-2 infection: a multicentre cohort study (PREDI-CO study)

2020 ◽  
Vol 26 (11) ◽  
pp. 1545-1553 ◽  
Author(s):  
Michele Bartoletti ◽  
Maddalena Giannella ◽  
Luigia Scudeller ◽  
Sara Tedeschi ◽  
Matteo Rinaldi ◽  
...  
Keyword(s):  
Cohort Study ◽  
Respiratory Failure ◽  
Prediction Model ◽  
Hospitalized Patients ◽  
Severe Respiratory Failure ◽  
Multicentre Cohort Study ◽  
Development And Validation ◽  
Multicentre Cohort

Development and Validation of SCOPE Score: A Clinical Score to Predict Progression to Severe Respiratory Failure in Hospitalized Patients With COVID-19 Pneumonia

2021 ◽  
Author(s):  
Evangelos Giamarellos-Bourboulis ◽  
Garyfallia Poulakou ◽  
Haralampos Milionis ◽  
Simeon Metallidis ◽  
Michalis Ploumidis ◽  
...  
Keyword(s):  
Respiratory Failure ◽  
Clinical Score ◽  
Hospitalized Patients ◽  
Severe Respiratory Failure ◽  
Development And Validation

scholarly journals Effects of tocilizumab on mortality in hospitalized patients with COVID-19: a multicentre cohort study

2020 ◽  
Author(s):  
Javier Martínez-Sanz ◽  
Alfonso Muriel ◽  
Raquel Ron ◽  
Sabina Herrera ◽  
José A. Pérez-Molina ◽  
...  
Keyword(s):  
Cohort Study ◽  
Hospitalized Patients ◽  
Multicentre Cohort Study ◽  
Multicentre Cohort

scholarly journals Short-term risk of liver and renal injury in hospitalized patients using micafungin: a multicentre cohort study

2016 ◽  
Vol 71 (10) ◽  
pp. 2938-2944 ◽  
Author(s):  
Sebastian Schneeweiss ◽  
Peggy L. Carver ◽  
Kausik Datta ◽  
Alicia Galar ◽  
Melissa D. Johnson ◽  
...  
Keyword(s):  
Cohort Study ◽  
Renal Injury ◽  
Hospitalized Patients ◽  
Short Term ◽  
Multicentre Cohort Study ◽  
Multicentre Cohort

scholarly journals Age differences in clinical features and outcomes in patients with COVID-19, Jiangsu, China: a retrospective, multicentre cohort study

BMJ Open ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. e039887 ◽  
Author(s):  
Huanyuan Luo ◽  
Songqiao Liu ◽  
Yuancheng Wang ◽  
Penelope A Phillips-Howard ◽  
Shenghong Ju ◽  
...  
Keyword(s):  
Cohort Study ◽  
Intensive Care ◽  
Respiratory Failure ◽  
Hospital Stay ◽  
Older Patients ◽  
Adverse Outcomes ◽  
Trend Test ◽  
Chronic Obstructive ◽  
Multicentre Cohort Study ◽  
Multicentre Cohort

ObjectivesTo determine the age-specific clinical presentations and incidence of adverse outcomes among patients with COVID-19 in Jiangsu, China.Design and settingRetrospective, multicentre cohort study performed at 24 hospitals in Jiangsu, China.Participants625 patients with COVID-19 enrolled between 10 January and 15 March 2020.ResultsOf the 625 patients (median age, 46 years; 329 (52.6%) men), 37 (5.9%) were children (18 years or younger), 261 (41.8%) young adults (19–44 years), 248 (39.7%) middle-aged adults (45–64 years) and 79 (12.6%) elderly adults (65 years or older). The incidence of hypertension, coronary heart disease, chronic obstructive pulmonary disease and diabetes comorbidities increased with age (trend test, p<0.0001, p=0.0003, p<0.0001 and p<0.0001, respectively). Fever, cough and shortness of breath occurred more commonly among older patients, especially the elderly, compared with children (χ2 test, p=0.0008, 0.0146 and 0.0282, respectively). The quadrant score and pulmonary opacity score increased with age (trend test, both p<0.0001). Older patients had many significantly different laboratory parameters from younger patients. Elderly patients had the highest proportion of severe or critically-ill cases (33.0%, χ2 test p<0.0001), intensive care unit use (35.4%, χ2 test p<0.0001), respiratory failure (31.6%, χ2 test p<0.0001) and the longest hospital stay (median 21 days, Kruskal–Wallis test p<0.0001).ConclusionsElderly (≥65 years) patients with COVID-19 had the highest risk of severe or critical illness, intensive care use, respiratory failure and the longest hospital stay, which may be due partly to their having a higher incidence of comorbidities and poor immune responses to COVID-19.

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