Needle EMG induced muscle bleeding complication after guideline approved discontinuation of anticoagulation

To ascertain whether to stop or continue aspirin before cataract surgery. Prospective observational study from July 2018 to June 2019. Information on pre-existing medical conditions like cardiac disease/stroke & use of Aspirin was obtained from patients posted for cataract surgery. Physical examination was done by physician & decided whether aspirin has to be stopped before surgery. Intra-operative and post-operative outcomes were recorded. SPSS 20.0 by using descriptive statistics i.e. only frequency and percentage. Out of 64 patients, 38 discontinued aspirin and 26 continued. In the group of patients who discontinued aspirin, 2 had bleeding complication in the form of bleeding from cut ends of conjunctiva. Where as in the group who continued aspirin 4 patients had bleeding complication. No thromboembolic events were recorded in both the groups. The risk of medical & ophthalmic events surrounding cataract surgery were so low that absolute differences in risk associated with changes in Aspirin use were minimal.

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Tu1045 PERIOPERATIVE HEPARIN BRIDGING FOR COLORECTAL EMR OR ESD FOR PATIENTS RECEIVING ANTICOAGULATION RESULTED IN A VERY HIGH INCIDENCE OF BLEEDING COMPLICATION

Gastrointestinal Endoscopy ◽

10.1016/j.gie.2018.04.2105 ◽

2018 ◽

Vol 87 (6) ◽

pp. AB508

Author(s):

Daisuke Yoshimura ◽

Toshiaki Ochiai ◽

Shin-ichiro Fukuda ◽

Kojiro Niho ◽

Yusuke Kitagawa ◽

...

Keyword(s):

Bleeding Complication ◽

High Incidence ◽

Very High

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Major bleeding complication rate of ultrasound-guided paracentesis in thrombocytopenic patients

Journal of Vascular and Interventional Radiology ◽

10.1016/j.jvir.2013.01.129 ◽

2013 ◽

Vol 24 (4) ◽

pp. S56

Author(s):

S. Reardon ◽

T.D. Atwell ◽

A. Lekah

Keyword(s):

Major Bleeding ◽

Complication Rate ◽

Bleeding Complication ◽

Ultrasound Guided ◽

Major Bleeding Complication

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Impact of antiplatelet therapy on increased blood loss and bleeding complication in patients undergoing urgent cholecystectomy for acute cholecystitis

HPB ◽

10.1016/j.hpb.2019.10.102 ◽

2019 ◽

Vol 21 ◽

pp. S549

Author(s):

T. Fujikawa ◽

Y. Yoshimoto ◽

Y. Kawamura ◽

T. Nishimura ◽

H. Kawamoto ◽

...

Keyword(s):

Blood Loss ◽

Acute Cholecystitis ◽

Antiplatelet Therapy ◽

Bleeding Complication

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PFA-100 closure times in preoperative screening in 500 pediatric patients

Thrombosis and Haemostasis ◽

10.1160/th06-09-0493 ◽

2007 ◽

Vol 98 (07) ◽

pp. 243-247 ◽

Cited By ~ 14

Author(s):

Birgit Roschitz ◽

Sigrid Thaller ◽

Martin Koestenberger ◽

Andrea Wirnsberger ◽

Bettina Leschnik ◽

...

Keyword(s):

Blood Cell ◽

Bleeding Complication ◽

Pediatric Patients ◽

Screening Method ◽

Outpatient Service ◽

Von Willebrand Disease ◽

Preoperative Screening ◽

Blood Cell Count ◽

Specific Diagnosis ◽

Von Willebrand

SummaryThree to five percent of patients undergoing surgery have either an acquired or congenital platelet defect or von Willebrand disease (vWD). The predictive value of preoperative coagulation screening is questionable. PFA-100 is now routinely used in preoperative screening in our pediatric outpatient service. We wanted to assess whether the PFA-100 would help to identify patients with primary haemostatic defects or if the additional use of PFA-100 would add to the problem of unnecessary pathologic preoperative laboratory values resulting in delay of surgical procedure. We investigated 500 children consecutively seen in our outpatient service before surgery. Blood cell count, aPTT, PFA-100 closure times (CT) were done in all patients. If abnormalities were found, the patient was presented to a haemostatic expert. vWF:AG, R:Cof and factorVIII were analysed in all patients with prolonged closure times and APTT values. One hundred twenty-six patients (25.2%) showed abnormalities in APTT and/or PFA-100. Further investigations in 89 of these 126 patients did not yield a specific diagnosis; neither diagnostic criteria for impaired haemostasis were found by questionnaire. None of these 89 patients had a bleeding complication during surgery. Forty-eight patients showed prolonged CTs. Twelve patients with low vWF:AG were detected, 10 of these patients were found by PFA-100. Four of these patients did present with normal APTT values. Our study shows that similar to the APTT the PFA-100 is probably only a good screening method when a haemostatic defect in a patient is clinically likely, especially to screen forVWD, and the test should not be used in general unselective screening.

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Effect Of Intracoronary And Systemic Thrombolysis With Streptokinase In Patients With Acute Myocardial Infarction And Unstable Angina Pectoris. On Coagulation Tests And Plasminogen

10.1055/s-0038-1652451 ◽

1981 ◽

Author(s):

H Kösteriag ◽

K L Neuhaus ◽

U Kasten ◽

J Schrader ◽

U Artmann ◽

...

Keyword(s):

Myocardial Infarction ◽

Acute Myocardial Infarction ◽

Blood Coagulation ◽

Coronary Arteries ◽

Bleeding Complication ◽

Coagulation System ◽

Bleeding Complications ◽

Small Decrease ◽

Mean Values ◽

Systemic Thrombolysis

Streptokinase, aplicated by intracoronary infusion in pat. with acute myocardial infarction has proven to be successfull in recanalisation of occluded coronary arteries. The good clinical, angiographic, chemical and EKG results suggests that jeopardized myocardium was salvaged by acute recanalisation. Till now, we infused Streptokinase (about 2000 U/min) in 78 pat. into the ischemia related occluded coronary artery. In this presentation we intend to demonstrate the results of these pat. and of a study, done before starting intracoronary Streptokinase infusion to be safe for bleeding complication. Neither after the infusion of 50 000 U.(n = 24) of 100 000 U. (n = 15) nor in 20 pat. who received SK equal to their ASTK-titres plus 50 000 U. SK whe found severe alterations of the blood-coagulation system. Only in the last group there was a small decrease of Fibrinogen of about 100 mg% and of Plasminogen 4 mg%. In none of the 78 pat., treated by intracoronary SK aplication, we resulted bleeding complication and the mean values of blood coagulation test remained within the normal range. On the other hand, we infused SK by veins and controlled the thrombolytic effect by coronarangiography. In 5 of 6 pat. we succeded in recanalisation of occluded coronary arteries within 45 Used very high dosages of SK, (about 2 Mill U) there was only a small decrease of 210 mg of Fibrinogen and no bleeding complications.

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P3672Assessment of ankle-brachial index to predict in-hospital bleeding complication and optimal duration of dual antiplatelet therapy in patients with acute coronary syndrome

European Heart Journal ◽

10.1093/eurheartj/ehy563.p3672 ◽

2018 ◽

Vol 39 (suppl_1) ◽

Author(s):

T Nakahashi ◽

K Sakata ◽

H Tada ◽

H Terai ◽

Y Horita ◽

...

Keyword(s):

Acute Coronary Syndrome ◽

Antiplatelet Therapy ◽

Bleeding Complication ◽

Dual Antiplatelet Therapy ◽

Ankle Brachial Index ◽

Coronary Syndrome ◽

Optimal Duration

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Defibrination Syndrome Developed after Replacement Therapy with PPSB in a Case of Hemophilia B.

10.1055/s-0039-1682504 ◽

1977 ◽

Author(s):

M. Kazama ◽

H. Iwakura ◽

M. Nakajima ◽

M. Abe ◽

T. Abe

Keyword(s):

Bleeding Complication ◽

Severe Pain ◽

Coagulation Factors ◽

Massive Bleeding ◽

Hemophilia B ◽

Valgus Osteotomy ◽

The Third ◽

Coagulation Tests ◽

Fresh Plasma ◽

Large Hematoma

A case of Hemophilia B, 20y., had valgus osteotomy of the left femoral neck. The preliminary replacement with PPSB was revealed not to introduce inhibitor and no other abnormal enzyme activity was found except for the slight disturbance of liver function. The operation was gotten ready with injection of 10 vials PPSB and performed smoothly in 2 hours with 340ml of blood loss. PPSB administration was scheduled in a daily dosis of 20 vials divided in twice. But at the third postoperative day, large hematoma concreted in the femoral region with severe pain and was followed by the massive bleeding from the wound. Coagulation tests revealed decreased platelet count, prolonged.PTT and prothrombin time, decreased fibrinogen and increased FDP. The concentration of F.IX was not lifted so high as expected after the injection of 10 vials of PPSB, which, together with the above mentioned changes of coagulation factors, suggested the developement of defibrination syndrome.The replacement of PPSB was continued together with 10,000 U of heparin and 800ml of fresh plasma per day. At the 7th postoperative day, the coagulation findings of defibrination syndrome were gradually improved, bleeding decreased and F. IX level elevated as could be calculated. The administration of PPSB was diminished and discontinued at 29th day and of heparin at 45th day without any bleeding complication thereafter.

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