Non-aqueous self-double-emulsifying drug delivery system: A new approach to enhance resveratrol solubility for effective transdermal delivery

Author(s):  
Caibiao Hu ◽  
Qiang Wang ◽  
Chaolong Ma ◽  
Qiang Xia
Author(s):  
Kusum Sharma ◽  
Asit Ranjan Sahu ◽  
Ankita Srivastava ◽  
Ruchi Shukla ◽  
Komal Rahevar ◽  
...  

2016 ◽  
Vol 78 (1) ◽  
pp. 2 ◽  
Author(s):  
PA Hannan ◽  
JA Khan ◽  
A Khan ◽  
S Safiullah

2020 ◽  
Vol 26 ◽  
Author(s):  
Drashti Patel ◽  
Bappaditya Chatterjee

: Transfersomes are bilayer vesicles composed of phospholipid and edge-activators, which are mostly surfactant. Transfersomes based drug delivery system has gained a lot of interest of the pharmaceutical researchers for their ability to improve drug penetration and permeation through the skin. Transdermal drug delivery via transfersomes has the potential to overcome the challenge of low systemic availability. However, this complex vesicular system has different issues to consider for developing a successful transdermal delivery system. One of the major ingredients, phospholipid has versatile sources and variable effect on the vesicle size and drug entrapment in transfersomes. The other one termed as edge-activator or surfactant has some crucial consideration of skin damage and toxicity depending upon its type and concentration. A complex interaction between type and concentration of phospholipid and surfactant was observed, which affect the physicochemical properties of transfersomes. This review focuses on the practical factors related to these two major ingredients such as phospholipid and surfactant. The origin, purity, desired concentration, the susceptibility of degradation, etc. are the important factors for selecting phospholipid. Regarding surfactants, the major aspects are type and desired concentration. A successful development of transfersomes based drug delivery system depends on the proper considerations of these factors and practical aspects.


Author(s):  
Asif Eqbal ◽  
Vaseem Ahamad Ansari ◽  
Abdul Hafeez ◽  
Farogh Ahsan ◽  
Mohd Imran ◽  
...  

Nanoemulsions are drug transporters for the delivery of therapeutic agents. They possess the small droplet size having the range of 20×10-9-200×10-9m. The main purpose of using Nanoemulsion is to enhance the drug bio- availability of transdermal drug delivery system. With the help of phase diagram, we can select the components of nanoemulsion depending upon formulas ratio of oil phase, surfactant/co-surfactant and water phase. Nanoemulsion directly used as a topical drug delivery in skin organs. The most useable pharmaceutical application has been developed till date to provide systemic effects to penetrating the full thickness of skin organ layer nanoemulsions can be administered through variety of routes such as percutaneous, perioral, topical, transdermal, ocular and parental administration of medicaments. Nanoemulsions are transparent and slightly opalescent. Nanoemulsion can be prepared through various methods. Nanoemulsions are transparent and slightly opalescent. Factor affecting nanoemulsions are surfactant, viscosity, lipophilic, drug content, pH, concentration of each component, and methodology of formulation. It is unfeasible to test all factors at the various levels. Design of formulation when it comes to experimental design it gives an excellent approach through reducing the time and money.


2017 ◽  
Vol 18 (10) ◽  
Author(s):  
Vinay Pandit ◽  
Ajay Kumar ◽  
Mahendra S. Ashawat ◽  
Chander P. Verma ◽  
Pravin Kumar

2018 ◽  
Vol 9 (1) ◽  
pp. 2604-2635
Author(s):  
Ankit Dugad . ◽  
Pravin Nalawade . ◽  
Ravindra Thakhre . ◽  
Sujit Kakade .

2013 ◽  
Vol 3 (2) ◽  
Author(s):  
Ravindra B Borade ◽  
Yogesh Y Mahajan ◽  
Nilesh P Jadhav ◽  
Jaiprakash V Kokane ◽  
Md. Rageeb Md. Usman ◽  
...  

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