A facile strategy to fabricate a pH-responsive mesoporous silica nanoparticle end-capped with amphiphilic peptides by self-assembly

2019 ◽  
Vol 179 ◽  
pp. 352-362 ◽  
Author(s):  
Fengfeng Zhao ◽  
Chen Zhang ◽  
Chenggui Zhao ◽  
Wei Gao ◽  
Xiaobo Fan ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Self Assembly ◽  
Silica Nanoparticle ◽  
Ph Responsive ◽  
Mesoporous Silica Nanoparticle ◽  
Amphiphilic Peptides

A redox-responsive mesoporous silica nanoparticle capped with amphiphilic peptides by self-assembly for cancer targeting drug delivery

Nanoscale ◽  
2015 ◽  
Vol 7 (22) ◽  
pp. 10071-10077 ◽  
Author(s):  
Dong Xiao ◽  
Hui-Zhen Jia ◽  
Ning Ma ◽  
Ren-Xi Zhuo ◽  
Xian-Zheng Zhang
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Cancer Cells ◽  
Self Assembly ◽  
Silica Nanoparticle ◽  
Cancer Targeting ◽  
Mesoporous Silica Nanoparticle ◽  
Amphiphilic Peptides ◽  
Redox Responsive

A novel redox-responsive mesoporous silica nanoparticle (RRMSN/DOX) capped with amphiphilic peptides by self-assembly was demonstrated for targeting drug delivery in cancer cells.

Sensitive fluorescence detection of heparin based on self-assembly of mesoporous silica nanoparticle–gold nanoclusters with emission enhancement characteristics

The Analyst ◽  
2018 ◽  
Vol 143 (22) ◽  
pp. 5388-5394 ◽  
Author(s):  
Lin Ma ◽  
Mengyue Zhang ◽  
Aijun Yang ◽  
Qin Wang ◽  
Fei Qu ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Fluorescence Detection ◽  
Self Assembly ◽  
Gold Nanoclusters ◽  
Silica Nanoparticle ◽  
Mesoporous Silica Nanoparticle ◽  
Emission Enhancement

Sensitive fluorescence detection of heparin based on self-assembly of mesoporous silica nanoparticle–gold nanoclusters with emission enhancement characteristics was reported.

A novel pH-responsive hollow mesoporous silica nanoparticle (HMSN) system encapsulating doxorubicin (DOX) and glucose oxidase (GOX) for potential cancer treatment

2019 ◽  
Vol 7 (20) ◽  
pp. 3291-3302 ◽  
Author(s):  
Kaiwu Cheng ◽  
Yu Zhang ◽  
Yaojia Li ◽  
Zhiguo Gao ◽  
Fanghui Chen ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Glucose Oxidase ◽  
Silica Nanoparticle ◽  
Treatment Modalities ◽  
Materials Chemistry ◽  
Single Treatment ◽  
Ph Responsive ◽  
Mesoporous Silica Nanoparticle ◽  
Hollow Mesoporous Silica ◽  
Potential Cancer

The multi-therapy modality is based on the combination and synergy of multiple single treatment modalities and materials chemistry.

Metal-Phenolic Encapsulated Mesoporous Silica Nanoparticles for pH-Responsive Drug Delivery and Magnetic Resonance Imaging

2018 ◽  
Vol 232 (9-11) ◽  
pp. 1733-1740 ◽  
Author(s):  
Yan Chen ◽  
Juan Wang ◽  
Jianhua Liu ◽  
Lehui Lu
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Mesoporous Silica Nanoparticles ◽  
Silica Nanoparticle ◽  
Burst Release ◽  
Acidic Environment ◽  
Ph Responsive ◽  
Resonance Imaging ◽  
Mesoporous Silica Nanoparticle ◽  
Longitudinal Relaxivity

Abstract The anticancer drug doxorubicin (DOX) is locked in the mesoporous silica nanoparticle by coating FeIII-TA polymer, and its burst release can be achieved under acidic environment, along with the decreased longitudinal relaxivity. This nanoplatform shows great potential to monitoring the drug delivery process and the fate of the nanocarrier.

Zwitterionic carbon dot-encapsulating pH-responsive mesoporous silica nanoparticles for NIR light-triggered photothermal therapy through pH-controllable release

2019 ◽  
Vol 7 (6) ◽  
pp. 2600-2610 ◽  
Author(s):  
Benny Ryplida ◽  
Gibaek Lee ◽  
Insik In ◽  
Sung Young Park
Keyword(s):  
Mesoporous Silica ◽  
Photothermal Therapy ◽  
Mesoporous Silica Nanoparticles ◽  
Silica Nanoparticle ◽  
Ph Responsive ◽  
Mesoporous Silica Nanoparticle ◽  
Carbon Dot ◽  
Image Guided ◽  
Nir Light ◽  
Controllable Release

Here, we designed a pH-responsive Indocyanine Green (ICG)-loaded zwitterionic fluorescent carbon dot (CD)-encapsulating mesoporous silica nanoparticle (MSN) for pH-tunable image-guided photothermal therapy.

Dual pH-responsive mesoporous silica nanoparticles for efficient combination of chemotherapy and photodynamic therapy

2015 ◽  
Vol 3 (23) ◽  
pp. 4707-4714 ◽  
Author(s):  
Xuemei Yao ◽  
Xiaofei Chen ◽  
Chaoliang He ◽  
Li Chen ◽  
Xuesi Chen
Keyword(s):  
Drug Delivery ◽  
Photodynamic Therapy ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Drug Delivery System ◽  
Delivery System ◽  
Mesoporous Silica Nanoparticles ◽  
Silica Nanoparticle ◽  
Ph Responsive ◽  
Mesoporous Silica Nanoparticle

By metallo-supramolecular coordinated interaction between Zn-Por and histidine, a dual pH-responsive mesoporous silica nanoparticle (MSN)-based drug delivery system has been fabricated for synergistic chemo-photodynamic therapy.

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