Retinoic acid-loaded solid lipid nanoparticles surrounded by chitosan film support diabetic wound healing in in vivo study

2020 ◽  
Vol 188 ◽  
pp. 110749 ◽  
Author(s):  
Valquíria T. Arantes ◽  
André A.G. Faraco ◽  
Frederico B. Ferreira ◽  
Cleida A. Oliveira ◽  
Elisângela Martins-Santos ◽  
...  
Keyword(s):  
Wound Healing ◽  
Retinoic Acid ◽  
Solid Lipid Nanoparticles ◽  
Chitosan Film ◽  
Lipid Nanoparticles ◽  
In Vivo Study ◽  
Diabetic Wound ◽  
Solid Lipid ◽  
Diabetic Wound Healing

Transdermal Delivery of Curcumin-Loaded Solid Lipid Nanoparticles as Microneedle Patch: an In Vitro and In Vivo Study

2022 ◽  
Vol 23 (1) ◽  
Author(s):  
Ankitha Prabhu ◽  
Jobin Jose ◽  
Lalit Kumar ◽  
S Salwa ◽  
M Vijay Kumar ◽  
...  
Keyword(s):  
Transdermal Delivery ◽  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
In Vivo Study ◽  
Solid Lipid ◽  
Microneedle Patch

scholarly journals HIBISCUS ROSA SINENSIS LOADED SOLID LIPID NANOPARTICLES AND IN VIVO WOUND HEALING ACTIVITY IN WISTAR ALBINO RATS

2020 ◽  
pp. 78-83
Author(s):  
VIJAYANAND P. ◽  
JYOTHI V. ◽  
MOUNIKA A.
Keyword(s):  
Wound Healing ◽  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Albino Rats ◽  
Herbal Extracts ◽  
Solid Lipid ◽  
Hibiscus Rosa Sinensis ◽  
Wistar Albino Rats ◽  
Wound Healing Activity

Objective: The objective of the present research was to investigate the wound-healing potency of solid lipid nano particles of Hibiscus rosa sinensis extract. Crude herbal extracts and rudimentary formulations containing herbal extracts are good for demonstrating the feasibility of the concept; however, such formulations suffer with poor oral bioavailability and variability within groups of subjects. Converting herbal extracts into novel drug delivery systems may prove effective in addressing some of these problems. Methods: In the present study an attempt was made to develop Hibiscus rosa sinensis extract loaded solid lipid nanoparticles (HSLNs) using lipids glycerol monostearate (GMS) or beeswax. The prepared HSLNs were characterised for their size, surface charge and morphology. The optimized HSLNs were incorporated into Carbopol gel and tested for wound healing activity in male Wistar albino rats using excision wound model. Results: HSLNs of ~175 nm in size carrying negative charge were obtained with the optimised procedure using beeswax. The shape of the HSLNs was nearly spherical. The HSLNs (10 mg/ml) treated wounds healed much faster compared to raw crude extract and healing was comparable to marketed preparation. Conclusion: It is concluded that converting crude herbal extracts into SLNs can be an effective way to enhance the effectiveness of herbal extracts and their in vivo activity.

scholarly journals Erratum to "Nanotechnology in Wound Healing; Semisolid Dosage Forms Containing Curcumin-Ampicillin Solid Lipid Nanoparticles, in Vitro, Ex Vivo and in Vivo Characteristics"

2020 ◽  
Vol 11 (1) ◽  
pp. 204-204
Author(s):  
Solmaz Ghaffari ◽  
Faezeh Alihosseini ◽  
Seyed Mahdi Rezayat Sorkhabadi ◽  
Sepideh Arbabi Bidgoli ◽  
Seyyedeh Elaheh Mousavi ◽  
...  
Keyword(s):  
Wound Healing ◽  
Solid Lipid Nanoparticles ◽  
Ex Vivo ◽  
Lipid Nanoparticles ◽  
Dosage Forms ◽  
Solid Lipid

In Vitro and in Vivo Study of Two Types of Long-Circulating Solid Lipid Nanoparticles Containing Paclitaxel

2001 ◽  
Vol 49 (11) ◽  
pp. 1444-1447 ◽  
Author(s):  
Da-Bing CHEN ◽  
Tian-zhi YANG ◽  
Wang-Liang LU ◽  
Qiang ZHANG
Keyword(s):  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
In Vivo Study ◽  
Solid Lipid

Silver Loaded Nanofibrous Curdlan Mat for Diabetic Wound Healing: An In Vitro and In Vivo Study

2018 ◽  
Vol 303 (9) ◽  
pp. 1800234 ◽  
Author(s):  
Rubaiya Yunus Basha ◽  
T. S. Sampath Kumar ◽  
Ramasamy Selvaraj ◽  
Mukesh Doble
Keyword(s):  
Wound Healing ◽  
In Vivo Study ◽  
Diabetic Wound ◽  
Diabetic Wound Healing

scholarly journals Nanotechnology in Wound Healing; Semisolid Dosage Forms Containing Curcumin-Ampicillin Solid Lipid Nanoparticles, in-Vitro, Ex-Vivo and in-Vivo Characteristics

2018 ◽  
Vol 8 (3) ◽  
pp. 395-400 ◽  
Author(s):  
Solmaz Ghaffari ◽  
Faezeh Alihosseini ◽  
Seyed Mahdi Rezayat Sorkhabadi ◽  
Sepideh Arbabi Bidgoli ◽  
Seyyedeh Elaheh Mousavi ◽  
...  
Keyword(s):  
Wound Healing ◽  
Solid Lipid Nanoparticles ◽  
Ex Vivo ◽  
Lipid Nanoparticles ◽  
Dosage Forms ◽  
Solid Lipid
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