scholarly journals Data regarding active psychosis and functional outcome, among other clinical variables, during early phases of the illness in first-episode psychosis in the PAFIP 10-year follow-up program

Data in Brief ◽  
2020 ◽  
Vol 30 ◽  
pp. 105599
Author(s):  
Guillermo Pardo-de-Santayana ◽  
Javier Vázquez-Bourgon ◽  
Marcos Gómez-Revuelta ◽  
Rosa Ayesa-Arriola ◽  
Victor Ortiz-Garcia de la Foz ◽  
...  
Keyword(s):  
Functional Outcome ◽  
First Episode Psychosis ◽  
First Episode ◽  
Clinical Variables ◽  
Episode Psychosis ◽  
Early Phases

Longitudinal changes of insight in first episode psychosis and its relation to clinical symptoms, treatment adherence and global functioning: One-year follow-up from the Eiffel study

2012 ◽  
Vol 27 (1) ◽  
pp. 43-49 ◽  
Author(s):  
R. Segarra ◽  
N. Ojeda ◽  
J. Peña ◽  
J. García ◽  
A. Rodriguez-Morales ◽  
...  
Keyword(s):  
Functional Outcome ◽  
Treatment Adherence ◽  
Rating Scales ◽  
Clinical Symptoms ◽  
Clinical Course ◽  
First Episode Psychosis ◽  
First Episode ◽  
Global Functioning ◽  
Episode Psychosis

AbstractObjectivesThe Eiffel study is a longitudinal, naturalistic study of patients with first episode psychosis (FEP) designed to evaluate the predictive value of defective insight on treatment adherence and global functioning.MethodsFive hundred seventy-seven patients with FEP were assessed at baseline and at a 1-year follow-up. They were compared in terms of sociodemographic factors, psychopathology, insight, treatment adherence and functional outcome. Longitudinal functionality was prospectively assessed with the clinical global impression (CGI) and global assessment of functioning (GAF) rating scales.ResultsAt baseline, up to 50% of our sample presented with a lack of insight. Most clinical symptoms, including insight, improved over the follow-up period. Insight, education and social withdrawal significantly predicted CGI and GAF at follow-up. Insight and level of education were predictive of treatment adherence.ConclusionsInsight significantly predicted the general clinical course, treatment adherence and functional outcome in our FEP sample after 1 year. Only education additionally accounted for the longitudinal course. Since our results suggest that better insight improves treatment adherence and consequently clinical course and functional outcome, insight could be a specific target of treatment in early intervention programs.

scholarly journals Longitudinal clinical and functional outcome in distinct cognitive subgroups of first-episode psychosis: a cluster analysis

2021 ◽  
pp. 1-11
Author(s):  
Priscilla P. Oomen ◽  
Marieke J. H. Begemann ◽  
Bodyl A. Brand ◽  
Lieuwe de Haan ◽  
Wim Veling ◽  
...  
Keyword(s):  
Cluster Analysis ◽  
Clinical Outcome ◽  
Functional Outcome ◽  
Functional Outcomes ◽  
Reference Group ◽  
First Episode Psychosis ◽  
First Episode ◽  
Whodas 2.0 ◽  
Episode Psychosis

Abstract Background Cognitive deficits may be characteristic for only a subgroup of first-episode psychosis (FEP) and the link with clinical and functional outcomes is less profound than previously thought. This study aimed to identify cognitive subgroups in a large sample of FEP using a clustering approach with healthy controls as a reference group, subsequently linking cognitive subgroups to clinical and functional outcomes. Methods 204 FEP patients were included. Hierarchical cluster analysis was performed using baseline brief assessment of cognition in schizophrenia (BACS). Cognitive subgroups were compared to 40 controls and linked to longitudinal clinical and functional outcomes (PANSS, GAF, self-reported WHODAS 2.0) up to 12-month follow-up. Results Three distinct cognitive clusters emerged: relative to controls, we found one cluster with preserved cognition (n = 76), one moderately impaired cluster (n = 74) and one severely impaired cluster (n = 54). Patients with severely impaired cognition had more severe clinical symptoms at baseline, 6- and 12-month follow-up as compared to patients with preserved cognition. General functioning (GAF) in the severely impaired cluster was significantly lower than in those with preserved cognition at baseline and showed trend-level effects at 6- and 12-month follow-up. No significant differences in self-reported functional outcome (WHODAS 2.0) were present. Conclusions Current results demonstrate the existence of three distinct cognitive subgroups, corresponding with clinical outcome at baseline, 6- and 12-month follow-up. Importantly, the cognitively preserved subgroup was larger than the severely impaired group. Early identification of discrete cognitive profiles can offer valuable information about the clinical outcome but may not be relevant in predicting self-reported functional outcomes.

scholarly journals Patterns and predictors of hospitalisation in first-episode psychosis

2001 ◽  
Vol 178 (6) ◽  
pp. 518-523 ◽  
Author(s):  
Attila Sipos ◽  
Glynn Harrison ◽  
David Gunnell ◽  
Shazad Amin ◽  
Swaran P. Singh
Keyword(s):  
Negative Symptoms ◽  
First Episode Psychosis ◽  
Psychiatric Services ◽  
First Episode ◽  
Psychotic Episode ◽  
Duration Of Untreated Illness ◽  
Specialist Services ◽  
Increased Risk ◽  
Episode Psychosis

BackgroundLittle is known about predictors of hospitalisation in patients with first-episode psychosis.AimsTo identify the pattern and predictors of hospitalisation of patients with a first psychotic episode making their first contact with specialist services.MethodThree-year follow-up of a cohort of 166 patients with a first episode of psychosis making contact with psychiatric services in Nottingham between June 1992 and May 1994.ResultsEighty-eight (53.0%) patients were admitted within 1 week of presentation; 32 (19.3%) were never admitted during the 3 years of follow-up. Manic symptoms at presentation were associated with an increased risk of rapid admission and an increased overall risk of admission; negative symptoms and a longer duration of untreated illness had an increased risk of late admission.ConclusionsCommunity-oriented psychiatric services might only delay, rather than prevent, admission of patients with predominantly negative symptoms and a longer duration of untreated illness. First-episode studies based upon first admissions are likely to be subject to selection biases, which may limit their representativeness.

Prediction of functional remission in first-episode psychosis: 12-month follow-up of the randomized-controlled trial on extended early intervention in Hong Kong

2016 ◽  
Vol 173 (1-2) ◽  
pp. 79-83 ◽  
Author(s):  
Wing Chung Chang ◽  
Vivian Wing Yan Kwong ◽  
Gloria Hoi Kei Chan ◽  
Olivia Tsz Ting Jim ◽  
Emily Sin Kei Lau ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Hong Kong ◽  
Early Intervention ◽  
Controlled Trial ◽  
First Episode Psychosis ◽  
First Episode ◽  
Randomized Controlled ◽  
Episode Psychosis

scholarly journals The dynamic relationship between insight and suicidal behavior in first episode psychosis patients over 3-year follow-up

2018 ◽  
Vol 28 (10) ◽  
pp. 1161-1172 ◽  
Author(s):  
Rosa Ayesa-Arriola ◽  
Jose María Pelayo Terán ◽  
Javier David López Moríñigo ◽  
Manuel Canal Rivero ◽  
Esther Setién-Suero ◽  
...  
Keyword(s):  
Suicidal Behavior ◽  
First Episode Psychosis ◽  
First Episode ◽  
Dynamic Relationship ◽  
Episode Psychosis

scholarly journals Pathways to care for first-episode psychosis in an early detection healthcare sector

2005 ◽  
Vol 187 (S48) ◽  
pp. s24-s28 ◽  
Author(s):  
Jan Olav Johannessen ◽  
Tor K. Larsen ◽  
Inge Joa ◽  
Ingrid Melle ◽  
Svein Friis ◽  
...  
Keyword(s):  
Early Detection ◽  
First Episode Psychosis ◽  
Healthcare Sector ◽  
Service Development ◽  
Pathways To Care ◽  
First Episode ◽  
Access To Treatment ◽  
Episode Psychosis ◽  
Low Threshold

BackgroundEarly detection programmes aim to reduce the duration of untreated psychosis (DUP) by public education and by prompt access to treatment via active outreach detection teams.AimsTo determine whether those with first-episode psychosis in an early detection healthcare area with existing referral channels differ from those who access care via detection teams.MethodThose with first-episode psychosis recruited via detection teams were compared with those accessing treatment via conventional channels, at baseline and after 3 months of acute treatment.ResultsPatients recruited via detection teams are younger males with a longer DUP a less dramatic symptom picture and better functioning; however they recover more slowly, and have more symptoms at 3-month follow-up.ConclusionsAfter establishing low threshold active case-seeking detection teams, we found clear differences between those patients entering treatment via detection teams v. those obtaining treatment via the usual channels. Such profiling may be informative for early detection service development.

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