Association between high sensitivity C-reactive protein and metabolic syndrome in subjects completing the National Health and Nutrition Examination Survey (NHANES) 2009–10

2014 ◽  
Vol 8 (2) ◽  
pp. 88-90 ◽  
Author(s):  
Stacy A. Voils ◽  
Rhonda M. Cooper-DeHoff
2003 ◽  
Vol 49 (8) ◽  
pp. 1353-1357 ◽  
Author(s):  
Earl S Ford ◽  
Wayne H Giles ◽  
Gary L Myers ◽  
Nader Rifai ◽  
Paul M Ridker ◽  
...  

Abstract Background: The distribution of C-reactive protein (CRP) concentrations among children and young adults in the US is not known at present. Methods: We used data from 3348 US children and young adults 3–19 years of age who participated in the National Health and Nutrition Examination Survey, 1999–2000, to describe the distribution of CRP concentrations, based on results obtained with a high-sensitivity latex-enhanced turbidimetric assay. Results: The range of CRP concentrations was 0.1–90.8 mg/L (mean, 1.6 mg/L; geometric mean, 0.5 mg/L; median, 0.4 mg/L). CRP concentrations increased with age. Females 16–19 years of age had higher concentrations than males in this age range (P = 0.003). Mexican Americans had the highest CRP concentrations among the three major race or ethnic groups (P <0.001). Conclusions: For the first time, these data describe the CRP concentration distribution among US children and young adults, based on results obtained with a high-sensitivity assay.


2020 ◽  
Author(s):  
Se-Won Park ◽  
Seong-Sik Park ◽  
Eun-Jung Kim ◽  
Won-Suk Sung ◽  
In-Hyuk Ha ◽  
...  

Abstract Background No studies have investigated the association between self-rated health (SRH) and high-sensitivity C-reactive protein (hs-CRP) in South Koreans. This study explored the association and analyzed any sex differences.Method Using data from the 2015-2017 Korea National Health and Nutrition Examination Survey, we analyzed the association between SRH and high group (>1.0 mg/L) in 14,544 Koreans aged ≥19 years who responded to the SRH survey and who had hs-CRP test results. Results The percentage of having a very poor to poor SRH was higher in the high hs-CRP level group (22.4%) than in the low level group (17.66%). Among males, the risk of a high hs-CRP level increased with worse SRH (adjusted for confounders; P for trend <0.001). After adjusting for all confounders, including chronic diseases, males with a very poor SRH showed higher odds ratio (OR) for high group than those with a very good SRH (fully adjusted OR, 1.74; 95% confidence interval, 1.04-2.90). Significant correlations were absent among females. Conclusions A poor SRH was correlated with low-grade inflammation (high hs-CRP level) among male Korean adults. The findings could be useful for developing health improvement programs and in goal setting at a national scale.


BMJ Open ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. e029861 ◽  
Author(s):  
Hyemin Jeong ◽  
Sun-Young Baek ◽  
Seon Woo Kim ◽  
Eun-Jung Park ◽  
Jaejoon Lee ◽  
...  

ObjectivePlasma C reactive protein (CRP) is a marker of inflammation, and increased plasma CRP is reported in many diseases, including cardiovascular disease, diabetes, metabolic syndrome, arthritis and malignancies. The aim of the study was to evaluate the association between plasma CRP levels and cardiovascular disease, metabolic syndrome, malignancies and other comorbidities.DesignA retrospective, cross-sectional survey study.SettingLarge population survey in Korea.MethodsA total of 5887 (weighted n=40 251 868) participants aged 19 years or older from the 2016 Korea National Health and Nutrition Examination Survey were included for analysis. Weighted prevalence and OR of comorbidities were analysed according to the continuous variable of log plasma high-sensitivity CRP levels.ResultsThe mean age was 46.7±0.37 years and the median plasma CRP was 0.58 mg/L (IQR 0.36–1.09). The mean plasma CRP levels were higher in participants with cardiovascular diseases and cardiovascular risk factors, osteoarthritis, rheumatoid arthritis, pulmonary tuberculosis, and several cancers, including gastric, colon, breast and cervix, than in the general population. In the multivariable analysis, plasma CRP concentration was associated with increased prevalence of hypertriglyceridaemia (OR 1.157, 95% CI 1.040 to 1.287, p=0.007), diabetes (OR 1.204, 95% CI 1.058 to 1.371, p=0.005) and metabolic syndrome (OR 1.228, 95% CI 1.112 to 1.357, p<0.001) after adjustment for socioeconomic and lifestyle characteristics. There was no significant association between plasma CRP level and cancers.ConclusionPlasma CRP was associated with an increased risk of dyslipidaemia, diabetes and metabolic syndrome in the general population.


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