Postpartum glucose testing, related factors and progression to abnormal glucose tolerance in a rural population with a known history of gestational diabetes

2017 ◽  
Vol 11 ◽  
pp. S455-S458 ◽  
Author(s):  
Haydeh Ghajari ◽  
Sedigheh Nouhjah ◽  
Hajieh Shahbazian ◽  
Rohollah Valizadeh ◽  
Noorollah Tahery
Keyword(s):  
Gestational Diabetes ◽  
Glucose Tolerance ◽  
Rural Population ◽  
Abnormal Glucose Tolerance ◽  
Related Factors ◽  
Glucose Testing ◽  
History Of

scholarly journals Prevalence of Abnormal Glucose Tolerance in Obese Pregnant Women - A Study from a Tertiary Care Centre

2021 ◽  
Vol 10 (44) ◽  
pp. 3769-3774
Author(s):  
Ann Mary George ◽  
Ajay Kumar
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Glucose Tolerance ◽  
Pregnant Women ◽  
Oral Glucose ◽  
Government Medical College ◽  
Abnormal Glucose Tolerance ◽  
Family History Of Diabetes ◽  
Medical College ◽  
History Of

BACKGROUND Obesity has emerged as an important risk factor in modern obstetrics and poses a major threat to pregnancy by causing complications including gestational diabetes. It also increases the risk of cardiovascular diseases and diabetes mellitus in later life. Obesity creates major technical challenges in providing maternity services too. The objective of the study was to assess the prevalence of abnormal glucose tolerance in obese pregnant women in a Government Medical College over one year. METHODS A prospective observational study was conducted among obese pregnant women, registered at the Outpatient department of Obstetrics and Gynaecology at the Government Medical College, Kottayam from January 2017 to December 2017. 450 women were considered for the study after satisfying inclusion and exclusion criteria. BMI was calculated using pre-pregnant weight. An oral glucose test was performed with 75 gm glucose at 24 to 28 weeks of pregnancy after 8 hours of fasting. International Association of Diabetes and Pregnancy Study Group cut-offs i.e., fasting blood sugar values more than 92 mg/dl, 1hr value more than 180 mg/dl, 2 hr value more than 153 mg/dl were used as the criteria. Oral glucose tolerance was considered abnormal if any of the above values were impaired. RESULTS The prevalence of abnormal glucose tolerance among the 450 pregnant women was 35.6 %. The incidence of abnormal GTT increased with increasing age and in those with a history of menstrual irregularities and infertility treatment. No relation was found between economic status, family history of diabetes, preeclampsia and abnormal GTT. CONCLUSIONS Obesity turns to be a menace in the reproductive life of women that begins by affecting the fertility, continues to cause complications in pregnancy, increases morbidity in the long-term future and reduces the quality of life. Since more than one-third of the study population was affected by gestational diabetes, active intervention to reduce the weight preconceptionally is needed. KEY WORDS Obesity, Glucose Tolerance Test, Gestational Diabetes Mellitus, Body Mass Index, Pregnancy

Abnormal Glucose Tolerance and Pregnancy Outcomes in Women Without Diagnosis of Gestational Diabetes Mellitus [23C]

2018 ◽  
Vol 131 ◽  
pp. 36S
Author(s):  
Christopher A. Enakpene ◽  
Tiffany Jones ◽  
Dimitrios Mastrogiannis ◽  
Micaela Della Torre ◽  
Lauren Knazze ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Glucose Tolerance ◽  
Gestational Diabetes Mellitus ◽  
Pregnancy Outcomes ◽  
Abnormal Glucose Tolerance

scholarly journals Diabetes and Abnormal Glucose Tolerance in Women With Previous Gestational Diabetes

Diabetes Care ◽  
2003 ◽  
Vol 26 (4) ◽  
pp. 1199-1205 ◽  
Author(s):  
M. Albareda ◽  
A. Caballero ◽  
G. Badell ◽  
S. Piquer ◽  
A. Ortiz ◽  
...  
Keyword(s):  
Gestational Diabetes ◽  
Glucose Tolerance ◽  
Abnormal Glucose Tolerance ◽  
Previous Gestational Diabetes

scholarly journals Inflammatory Markers in Older Women with a History of Gestational Diabetes and the Effects of Weight Loss

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Alice S. Ryan
Keyword(s):  
Weight Loss ◽  
Body Composition ◽  
Gestational Diabetes ◽  
Glucose Tolerance ◽  
Older Women ◽  
Inflammatory Markers ◽  
Normal Glucose Tolerance ◽  
Diet And Exercise ◽  
Normal Glucose ◽  
History Of

The purpose of this study was to compare systemic inflammation in older women with a history of gestational diabetes (GDM) who developed impaired glucose tolerance (IGT) or type 2 diabetes (T2DM) to that in those with normal glucose tolerance (NGT) and to determine, in these women, the effect of weight loss (WL) induced by diet and exercise training on systemic inflammation and adipokine levels. This was a longitudinal clinical investigation of overweight/obese (BMI: 32 ± 1 kg/m2) women (59 ± 1 years) with a GDM history (n=19) who had normal glucose tolerance (NGT, n=7) or IGT/T2DM (n=12). Women completed 6 months of weight loss induced by diet and exercise and underwent VO2max, body composition, blood draw, glucose tolerance testing, and 2-hour hyperinsulinemic-euglycemic clamps (40 mU·m−2·min−1). Glucose utilization (M) was 42% higher in the NGT group (P<0.05). CRP was two-fold higher in the IGT/T2DM group than that in the NGT group (P<0.01). Adiponectin levels were 59% higher in the NGT group than those in the IGT/T2DM group (P<0.01). IL-6sR was higher in the NGT group (P<0.01). The women lost body weight, body fat, visceral fat, and subcutaneous abdominal fat (P<0.001). Fasting glucose (P<0.05), fasting insulin, glucose, and insulin AUC decreased (all P<0.005) after the intervention. M increased by 21% (P<0.05). CRP (−16%) and TNFR1 (−6%) tended to decrease, whereas TNFα, IL-6, SAA, and adiponectin did not change in the group. In conclusion, older women with a history of GDM who have developed IGT or T2DM have higher CRP and reduced adiponectin levels despite similar BMI and total and abdominal obesity to those with NGT. Six months WL induced by diet and exercise improves body composition and increases insulin sensitivity without a significant modification of inflammatory markers and adiponectin levels.

scholarly journals Serum Homocysteine Level Might Be a Predictor for Persistence of Abnormal Glucose Tolerance in Gestational Diabetes

2021 ◽  
Vol 6 (2) ◽  
pp. 58
Author(s):  
Shradha Shrestha ◽  
Sharmin Jahan ◽  
Nusrat Sultana ◽  
Mohammad Fakhrul Alam ◽  
Yasmin Akter ◽  
...  
Keyword(s):  
Gestational Diabetes ◽  
Glucose Tolerance ◽  
Homocysteine Level ◽  
Abnormal Glucose Tolerance ◽  
Serum Homocysteine

Barriers to Postpartum Glucose Testing in Women with Gestational Diabetes Mellitus

2018 ◽  
Vol 36 (02) ◽  
pp. 212-218 ◽  
Author(s):  
Phinnara Has ◽  
Lindsey Kanno ◽  
Adam Sullivan ◽  
Melissa Clark ◽  
Erika Werner
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Private Insurance ◽  
Health Agency ◽  
Postpartum Women ◽  
College Degrees ◽  
Glucose Testing ◽  
History Of ◽  
Household Incomes

Objective To identify barriers to postpartum glucose testing in women with a history of gestational diabetes mellitus (GDM). Materials and Methods This is a prospective cohort study of 300 women with GDM who completed questionnaires on socioeconomic barriers and validated instruments to measure trust in their clinician and health agency. At 12 weeks' postpartum, women were recontacted and postpartum records were collected. Women who completed glucose testing between 4 and 12 weeks' postpartum were compared with women who did not with regard to modifiable and nonmodifiable barriers to care. Results Of the 373 women approached, 300 (80%) consented to participate, completed surveys on postpartum day 2, and had records retrieved at 12 weeks' postpartum. Validated instruments used showed internal consistency (Cronbach's α > 0.6). Only 126 (42%) of the participants completed postpartum glucose testing, and these women were more likely to have reliable transportation, private insurance, college degrees, and higher annual household incomes (p < 0.05). Postpartum glucose testing was also associated with trust in clinicians (p = 0.01) but not health agency (p = 0.66). The association between trust and postpartum glucose testing persisted after adjusting for nonmodifiable barriers. Conclusion Maximizing trust in clinicians should be a focus of prenatal GDM care to maximize the likelihood of postpartum glucose testing.

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