Outcomes after central grey matter injury in term perinatal hypoxic-ischaemic encephalopathy

2010 ◽  
Vol 86 (11) ◽  
pp. 675-682 ◽  
Author(s):  
Miriam Martinez-Biarge ◽  
Jesus Diez-Sebastian ◽  
Mary A. Rutherford ◽  
Frances M. Cowan
2012 ◽  
Vol 321 (1-2) ◽  
pp. 111-113 ◽  
Author(s):  
Pratik Bhattacharya ◽  
Fen Bao ◽  
Megha Shah ◽  
Gautam Ramesh ◽  
Ramesh Madhavan ◽  
...  

2010 ◽  
Vol 68 ◽  
pp. 89-89
Author(s):  
M Martinez-Biarge ◽  
J Diez-Sebastian ◽  
S Lawrence ◽  
A Aloysius ◽  
M A Rutherford ◽  
...  

1987 ◽  
Vol 151 (6) ◽  
pp. 744-752 ◽  
Author(s):  
Bente Pakkenberg

Volume measurements were carried out on 29 brains from institutionalised, chronic schizophrenic patients and 30 age and sex-matched controls using a stereological method. The volumes of the total fixated brain, the hemispheres, the cortex, and the central grey matter of the schizophrenic brains were significantly reduced while the volumes of the ventricles were significantly enlarged compared with the control group. The patients had been diagnosed by a psychiatrist on the basis of their case records as having either a Type I or Type II syndrome according to the symptoms they presented in the first years of their disease. The Type II patients were found to have significantly enlarged ventricles compared with the Type I patients.


2008 ◽  
Vol 212 (S 1) ◽  
Author(s):  
A van Baalen ◽  
S Landowski ◽  
T Müller ◽  
E Kruppa ◽  
R Bohn ◽  
...  

1997 ◽  
Vol 16 (4) ◽  
pp. 657-690 ◽  
Author(s):  
Vera Maura Fernandes de Lima ◽  
Wolfgang Hanke

2020 ◽  
Vol 25 (3) ◽  
pp. 61
Author(s):  
Christophe Bastien ◽  
Clive Neal-Sturgess ◽  
Huw Davies ◽  
Xiang Cheng

In the real world, the severity of traumatic injuries is measured using the Abbreviated Injury Scale (AIS). However, the AIS scale cannot currently be computed by using the output from finite element human computer models, which currently rely on maximum principal strains (MPS) to capture serious and fatal injuries. In order to overcome these limitations, a unique Organ Trauma Model (OTM) able to calculate the threat to the life of a brain model at all AIS levels is introduced. The OTM uses a power method, named Peak Virtual Power (PVP), and defines brain white and grey matter trauma responses as a function of impact location and impact speed. This research has considered ageing in the injury severity computation by including soft tissue material degradation, as well as brain volume changes due to ageing. Further, to account for the limitations of the Lagrangian formulation of the brain model in representing hemorrhage, an approach to include the effects of subdural hematoma is proposed and included as part of the predictions. The OTM model was tested against two real-life falls and has proven to correctly predict the post-mortem outcomes. This paper is a proof of concept, and pending more testing, could support forensic studies.


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