Hedgehog pathway inhibitors of the acylthiourea and acylguanidine class show antitumor activity on colon cancer in vitro and in vivo

2018 ◽  
Vol 157 ◽  
pp. 368-379 ◽  
Author(s):  
Loredana Vesci ◽  
Ferdinando Maria Milazzo ◽  
Maria Antonietta Stasi ◽  
Silvia Pace ◽  
Francesco Manera ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Antitumor Activity ◽  
Hedgehog Pathway

In vitro and in vivo antitumor activity of Yerba Mate extract in colon cancer models

2020 ◽  
Vol 85 (7) ◽  
pp. 2186-2197 ◽  
Author(s):  
Rocio S. Garcia‐Lazaro ◽  
Humberto Lamdan ◽  
Lorena G. Caligiuri ◽  
Norailys Lorenzo ◽  
Andrea L. Berengeno ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Antitumor Activity ◽  
Yerba Mate ◽  
Cancer Models ◽  
In Vivo Antitumor Activity

scholarly journals In Vitro and in Vivo antitumor activity and the mechanism of siphonodictyal B in human colon cancer cells

2019 ◽  
Vol 8 (12) ◽  
pp. 5662-5672 ◽  
Author(s):  
Sonoko Chikamatsu ◽  
Ken Saijo ◽  
Hiroo Imai ◽  
Koichi Narita ◽  
Yoshifumi Kawamura ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Antitumor Activity ◽  
Cancer Cells ◽  
Human Colon ◽  
Colon Cancer Cells ◽  
Human Colon Cancer ◽  
In Vivo Antitumor Activity ◽  
Human Colon Cancer Cells

scholarly journals Evaluation of antitumor activity of survivin short interfering RNA delivered by lipid nanoparticles in colon cancer in vitro and in vivo

2017 ◽  
Vol 14 (2) ◽  
pp. 2001-2008 ◽  
Author(s):  
Tianyou Wang ◽  
Ziqin Liu ◽  
Zhaoxia Zhang ◽  
Suoqin Tang ◽  
Mei Yue ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Antitumor Activity ◽  
Lipid Nanoparticles ◽  
Short Interfering Rna ◽  
Interfering Rna

Antitumor Activity of Capsaicin on Human Colon Cancer Cells in Vitro and Colo 205 Tumor Xenografts in Vivo

2010 ◽  
Vol 58 (24) ◽  
pp. 12999-13005 ◽  
Author(s):  
Hsu-Feng Lu ◽  
Yuan-Liang Chen ◽  
Jai-Sing Yang ◽  
Yi-Yuan Yang ◽  
Jia-You Liu ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Antitumor Activity ◽  
Cancer Cells ◽  
Human Colon ◽  
Colon Cancer Cells ◽  
Human Colon Cancer ◽  
Tumor Xenografts ◽  
Human Colon Cancer Cells

ANTITUMOR EFFECT OF COLLOIDAL SILVER BISILICATE IN EXPERIMENTAL IN VITRO AND IN VIVO STUDIES

2019 ◽  
Vol 65 (5) ◽  
pp. 760-765
Author(s):  
Margarita Tyndyk ◽  
Irina Popovich ◽  
A. Malek ◽  
R. Samsonov ◽  
N. Germanov ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Tumor Growth ◽  
Tumor Cells ◽  
Human Tumor ◽  
Significant Inhibition ◽  
In Vivo Studies ◽  
Ehrlich Carcinoma ◽  
In Vivo Experiments

The paper presents the results of the research on the antitumor activity of a new drug - atomic clusters of silver (ACS), the colloidal solution of nanostructured silver bisilicate Ag6Si2O7 with particles size of 1-2 nm in deionized water. In vitro studies to evaluate the effect of various ACS concentrations in human tumor cells cultures (breast cancer, colon carcinoma and prostate cancer) were conducted. The highest antitumor activity of ACS was observed in dilutions from 2.7 mg/l to 5.1 mg/l, resulting in the death of tumor cells in all studied cell cultures. In vivo experiments on transplanted Ehrlich carcinoma model in mice consuming 0.75 mg/kg ACS with drinking water revealed significant inhibition of tumor growth since the 14th day of experiment (maximally by 52% on the 28th day, p < 0.05) in comparison with control. Subcutaneous injections of 2.5 mg/kg ACS inhibited Ehrlich's tumor growth on the 7th and 10th days of the experiment (p < 0.05) as compared to control.

Large volume spark discharge and plasma jet-technology for generating plasma-oxidized saline targeting colon cancer in vitro and in vivo

2021 ◽  
Vol 129 (5) ◽  
pp. 053301
Author(s):  
Eric Freund ◽  
Lea Miebach ◽  
Ramona Clemen ◽  
Michael Schmidt ◽  
Amanda Heidecke ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Large Volume ◽  
Plasma Jet ◽  
Spark Discharge
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