scholarly journals SAT-089 BIOPSY-FREE DIFFERENTIAL DIAGNOSIS MODEL OF MALIGNANT HYPERTENSION WITH RENAL INVOLVEMENT

2020 ◽  
Vol 5 (3) ◽  
pp. S40
Author(s):  
C. PU ◽  
C. Guangyan ◽  
X. Yuansheng ◽  
W. Jie ◽  
L. Shuwen ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Renal Involvement ◽  
Malignant Hypertension ◽  
Diagnosis Model

Unusual renal involvement of polymyositis complicated with malignant hypertension

1999 ◽  
Vol 9 (4) ◽  
pp. 381-390
Author(s):  
Mika Watanabe ◽  
Makoto Takahashi ◽  
Takashi Sawai
Keyword(s):  
Renal Involvement ◽  
Malignant Hypertension

Unusual renal involvement of polymyositis complicated with malignant hypertension

1999 ◽  
Vol 9 (4) ◽  
pp. 381-390
Author(s):  
Mika Watanabe ◽  
Makoto Takahashi ◽  
Takashi Sawai
Keyword(s):  
Renal Involvement ◽  
Malignant Hypertension

scholarly journals Multiple Hypovascular Tumors in Kidney: A Rare Case Report and Differential Diagnosis

2013 ◽  
Vol 2013 ◽  
pp. 1-4
Author(s):  
Pei-Yu Wu ◽  
Sheng-Fung Lin ◽  
Ping-Hsun Wu ◽  
Yi-Chun Tsai ◽  
Yu-Ting Kuo ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Ct Scan ◽  
Renal Mass ◽  
Renal Involvement ◽  
Image Study ◽  
Renal Lymphoma ◽  
Apparent Diffusion ◽  
Rare Case Report ◽  
Magnetic Resonance Imaging Mri ◽  
Mri Image

The most common malignant renal tumor is renal cell carcinoma and surgery is the standard treatment. The proportion of lymphoma with renal involvement is 2~15% and lymphoma could be cured by chemotherapy without nephrectomy. Sonography, computed tomography (CT), and magnetic resonance imaging (MRI) can detect and characterize a renal mass. We present a case of right renal hypovascular tumors and differential diagnosis of hypovascular tumors by image study. CT scan showed hypovascular tumors and MRI image revealed multifocal hypovascular solid tumors with significantly increased apparent diffusion coefficient (ADC) of diffusion weighted imaging (DWI). Based on image finding, renal lymphoma was highly suspected. Renal lymphoma was confirmed by renal biopsy and this patient received chemotherapy without surgery. The noninvasive CT scan and MRI image can help clinicians to diagnose the characteristics of renal mass and to avoid unnecessary nephrectomy.

scholarly journals Laparoscopic management of renal and hepatic hydatidosis in a child: a case report and review of literature

2017 ◽  
Vol 4 (5) ◽  
pp. 1793
Author(s):  
Rajashekhar T. Patil ◽  
Sandesh V. Parelkar ◽  
Beejal Sanghvi
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Laparoscopic Surgery ◽  
Renal Involvement ◽  
The Body ◽  
Cystic Disease ◽  
Review Of Literature ◽  
Intermediate Hosts ◽  
Hepatic Hydatidosis ◽  
First Case

Hydatidosis is an endemic disease caused by Echinococcus granulosus. Humans are accidental intermediate hosts. In children, it affects the lung in 64% of cases and the liver in 28%. Renal involvement is uncommon (2-4%). We operated 7 years old girl with renal and hepatic hydatidosis laparoscopically. Hydatid cyst should be kept as one of differential diagnosis while managing cystic disease of any organ in the body. To the best of our knowledge this is the first case of renal hydatidosis with hepatic hydatidosis that has been managed laparoscopically. Laparoscopic surgery is safe and efficacious in managing multiorgan hydatid disease in children.

Abstract P539: Cardiac and Renal Involvement in Malignant-accelerated Hypertension: Implications on Long-term Survival

Hypertension ◽  
2017 ◽  
Vol 70 (suppl_1) ◽  
Author(s):  
Luiz Bortolotto ◽  
Jose J De Lima ◽  
Dante Giorgi
Keyword(s):  
Arterial Hypertension ◽  
Cox Regression ◽  
Renal Involvement ◽  
Severe Complication ◽  
Malignant Hypertension ◽  
Term Survival ◽  
Long Term Survival ◽  
Cox Regression Analysis ◽  
Short Period

Background: Malignant hypertension is a severe complication of arterial hypertension where end-organ damage is severe and occurs in a short period of time. Data about cardiac and renal involvement and implications on long-term survival of patients with malignant hypertension are scarce. Methods: We performed a single-centre retrospective analysis of 176 patients with malignant hypertension, diagnosed in the period 1984-2007. Results: Incidence of malignant hypertension decreased along the different periods of the study, but cardiac and renal damage at presentation were common and severe. In 94.6% we observed left ventricle hypertrophy on echocardiogram, in 83.2% the glomerular filtration rate was below 60 ml/min/1.73m2 and 11% of patients required immediate dialysis. The survival rate was 95% at 6 months, 90% at 12 months, 81% at 36 months, and 67% at 5-year follow-up. In a Cox-regression analysis, the independent predictors of all-cause mortality were age, SBP at discharge, septum wall thickness values and GFR at admission. Conclusion: Malignant hypertension remains a severe complication of arterial hypertension with a high mortality rate at 5-year, that was independently associated to the severe cardiac and renal involvement present in most patients.

scholarly journals Pathology of Antineutrophil Cytoplasmic Antibody–Associated Pulmonary and Renal Disease

2017 ◽  
Vol 141 (2) ◽  
pp. 223-231 ◽  
Author(s):  
Maxwell L. Smith
Keyword(s):  
Differential Diagnosis ◽  
Renal Disease ◽  
Clinical Laboratory ◽  
Tissue Injury ◽  
Renal Involvement ◽  
Antineutrophil Cytoplasmic Antibody ◽  
Small Vessel Vasculitis ◽  
Antibody Testing ◽  
Anca Associated Vasculitis ◽  
Histopathologic Diagnosis

Context.—Antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis commonly presents with pulmonary and renal involvement that may present diagnostic challenges. Objectives.—To highlight the updates in the classification of small vessel vasculitis, present the patterns of pulmonary and renal pathology in which ANCA-associated vasculitis is included in the differential diagnosis, analyze the screening and specific antineutrophil cytoplasmic antibody testing methods in the clinical laboratory, compare and contrast the 3 major ANCA-associated vasculitis diseases, and review the pathophysiologic mechanisms of tissue injury in this setting. Data Sources.—Data are derived from published literature and clinical experience. Conclusions.—Although rare, ANCA-associated vasculitis diseases are often considered in the differential diagnosis of many pathologic patterns of pulmonary and renal disease. Histopathologic diagnosis of specific entities in this context nearly always requires correlation of the pathology with clinical and serologic data.

scholarly journals 1338. Development of a Novel Application for Differential Diagnosis of Tick-borne Diseases

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S484-S485
Author(s):  
Corey Meyer ◽  
Jaleal Sanjak ◽  
Audrey Cerles ◽  
Christian Garnier ◽  
Laurel MacMillan
Keyword(s):  
Risk Factors ◽  
Differential Diagnosis ◽  
Environmental Risk ◽  
Risk Measure ◽  
Diagnostic Testing ◽  
Biomedical Literature ◽  
Infection Prevalence ◽  
Surveillance Systems ◽  
Tick Infection ◽  
Diagnosis Model

Abstract Background Early diagnosis and treatment of tick-borne diseases (TBDs) is critical for mitigating their adverse health outcomes, but the differential diagnosis of TBDs is challenging because many symptoms are nonspecific and commonly used diagnostic assays have significant shortcomings. Furthermore, although the local incidence of TBDs is recognized as an important factor in diagnosis, tools to help clinicians formally consider surveillance data in their decision-making are not available. To address these gaps, Gryphon Scientific developed a differential diagnosis application (app) for TBDs that calculates a patient’s likelihood of infection with specific TBDs based on their symptoms, risk factors, and state of suspected tick exposure. Methods A differential diagnosis model for TBDs was developed using data on: (1) TBD symptom and risk factor prevalence in TBD patient populations, collected from clinical studies; and (2) human TBD incidence data from notifiable disease surveillance systems and tick infection prevalence data from reports and public databases, which were combined to develop an environmental risk measure. These data were used to build a Bayesian Belief Network (BBN) model that predicts TBD infection probabilities based on a patient’s symptoms, risk factors, and state of suspected tick exposure. Performance of the model was validated using case studies from the biomedical literature. The model was incorporated into an app developed using R-shiny, called TBD-DDx (Figures 1 and 3). Results A pilot application was developed that includes 10 states (AR, CT, MA, ME, MN, MO, NH, RI, VT, and WI) and the 11 TBDs endemic to those states. The differential diagnosis model identified the patient’s true disease as the top-predicted disease in 56% of cases and within the top three predicted TBD in 84% of cases. The inclusion of incidence factors in the model improved performance (Figure 4). Conclusion These results demonstrate that the TBD-DDx app is a promising tool for informing clinical diagnoses of TBDs to guide selection of diagnostic testing and treatment. This study represents the first use of a BBN modeling approach that incorporates an environmental risk measure and could be adapted for differential diagnosis of other diseases with environmental or other exposure risks. Disclosures All authors: No reported disclosures.

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