scholarly journals SUN-214 CLINICAL PROFILE OF END STAGE RENAL DISEASE IN PATIENTS ON MAINTENANCE HEMODIALYSIS IN A TERTIARY HOSPITAL

2020 ◽  
Vol 5 (3) ◽  
pp. S288
Author(s):  
D. DHUNGANA ◽  
B. Banstola
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Tertiary Hospital ◽  
Clinical Profile ◽  
Maintenance Hemodialysis ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Clinical profile of end stage renal disease in patients on maintenance haemodialysis in a tertiary hospital

2020 ◽  
Vol 13 (2) ◽  
pp. 169-172
Author(s):  
Durga Dhungana ◽  
Chandra Bahadur Pun ◽  
Bidhya Banstola
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Tertiary Hospital ◽  
Clinical Profile ◽  
Female Ratio ◽  
Maintenance Haemodialysis ◽  
Stage Renal Disease ◽  
End Stage

Introduction and Objectives: Chronic kidney disease is an increasing health problem worldwide and the burden of such patients is increasing in developing countries like Nepal as well. The final treatment for End Stage Renal Disease is only renal replacement therapy. The objective was to study the demographic and clinical profile of patients with End Stage Renal Disease undergoing haemodialysis. Methods: This was a prospective, observational study carried out in a tertiary hospital after obtaining ethical consent from the Institutional Review Board. The study period was from June 1st to August 31st, 2019. Thirty seven patients, older than 15 years who were on maintenance haemodialysis on regular basis in the hospital for at least 3 months were selected for the study. Patient’s records were used for the data collection as well as direct questionnaire to the patients on follow up for routine haemodialysis. Data were entered into Statistical Package for the Social Sciences 21 and descriptive analysis was done. Results: Twenty-six patients were under 50 years with male: female ratio of 1.64:1. Mean duration of haemodialysis of patients was 3.82 years. Most common cause for end stage renal disease was hypertension followed by idiopathic cause. Anaemia and hypocalcaemia were found to be the common complications associated with the patients. Conclusions: Prevention and early treatment may be the key to decrease the incidence of chronic kidney disease patients and also halt the progression to End stage renal disease.  

P1379PLATELET/LYMPHOCYTE RATIO AS A MARKER OF ERYTHROPOIETIN RESPONSIVENESS IN END-STAGE RENAL DISEASE

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Sonja Golubović ◽  
Tijana Azasevac ◽  
Siniša Živković ◽  
Bojana Ljubiäiä‡ ◽  
Violeta Knezevic ◽  
...  
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Laboratory Data ◽  
Moderate Intensity ◽  
Maintenance Hemodialysis ◽  
Weekly Dose ◽  
Lymphocyte Ratio ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esa Therapy

Abstract Background and Aims Neutrophil/Lymphocyte Ratio (NLR) and Platelet/Lymphocyte Ratio (PLR) are closely associated with increased inflammation in end-stage renal disease, which often contributes to the severity of anemia in these patients. Erythropoiesis stimulating agents (ESA) have become a standard treatment of anemia in hemodialysis patients. Since some patients do not respond well to erythropoietin therapy (EPO) the aim of this study is to investigate if NLR and PLR as markers of increased inflammation, could be associated with resistance to EPO therapy. Method A total of 90 patients (36 females, 54 males; mean age 60,45 ±11,58) undergoing maintenance hemodialysis and who received recombinant human EPO therapy were examined. Patients' clinical characteristics, laboratory data, dialysis adequacy and the applied doses os EPO were examined in a period of 3 months. EPO hyporesponsiveness index (EHRI) was calculated as the weekly dose of EPO divided by kilograms of body weight divided by the hemoglobin level. Results Obtained results show a statistically significant correlation of moderate-intensity between EHRI and NLR ( r = 0.497, p < 0.01) as well as a negative correlation of moderate-intensity between EHRI and hemoglobin levels (Hgb) (r = -0.403, p < 0.01). When it comes to the connection of NLR and PLR with logarithmically converted EHRI values, the results show that there is no statistically significant correlation between NLR and EHRI. Comparison of PLR among 25th, 50th and 75th percentile of EHRI showed that PLR levels increased going from the 25th towards the 75th percentile (p < 0.01). Post hoc analysis indicated that there is also a statistically strong connection for the 25th i 50th percentile (<0 .05) and furthermore for the 50th and 75th percentile (< 0.05). Conclusion PLR was found to be superior to NLR in terms of evaluating ESA therapy resistance. PLR could be used as a predictor of ESA therapy response.

scholarly journals Acute Intradialytic Complications in End Stage Renal Disease on Maintenance Hemodialysis

2012 ◽  
Vol 52 (187) ◽  
Author(s):  
R K Agrawal ◽  
S Khakurel ◽  
R Hada ◽  
D Shrestha ◽  
A Baral
Keyword(s):  
Renal Failure ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Maintenance Hemodialysis ◽  
Care Hospital ◽  
Cross Sectional ◽  
Stage Renal Disease ◽  
End Stage

Introduction: Hemodialysis is the preferred method of treatment for Nepalese patients with End Stage Renal Disease. Despite the technological advances and better understanding of physiology associated with hemodialysis, a number of complications are known to be associated with hemodialysis. This study was undertaken to study the frequency of acute intradialytic complications in patients undergoing hemodialysis. Methods: A cross-sectional study was conducted at Nephrology unit of a tertiary care hospital from 15 June, 2007 to 15 December, 2007. A total of 28 patients were included in the study. Patients with acute renal failure and acute on chronic renal failure were excluded from the study. Results: Total sessions of hemodialysis during the period were 1455. Hypotensive episode were 66 (4.5%) and was the commonest complication and followed by hypertensive episodes were 58 (3.8%). Other problems encountered were transfusion reactions were 23 episodes (1.5%), rigors not related to transfusions were 13 episodes (0.8%), nausea/vomiting were 20 episodes (1.4%), muscle cramps were 12 episodes (0.8%), hypoglycemia were 6 episodes 5(0.4%). Conclusions: The frequency of intradialytic complications is low and many of them are not life threatening. Keywords: complications; end stage renal disease; hemodialysis; hypertension; hypotension.

scholarly journals Frequency of Intradialytic Complications in Patients of End-Stage Renal Disease on Maintenance Hemodialysis

Cureus ◽  
2021 ◽  
Author(s):  
Muhammad Ali ◽  
Ayesha Ejaz ◽  
Hina Iram ◽  
Shafique A Solangi ◽  
Abdul Manan Junejo ◽  
...  
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Maintenance Hemodialysis ◽  
Stage Renal Disease ◽  
End Stage

Aiming for the optimal bicarbonate prescription for maintenance hemodialysis therapy in end‐stage renal disease

2019 ◽  
Vol 23 (2) ◽  
pp. 173-180 ◽  
Author(s):  
Andreas Bozikas ◽  
Iliana Kiriakoutzik ◽  
Ioannis Petrou ◽  
Theodoros Touroutzis ◽  
Eleni Kitoukidi ◽  
...  
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Maintenance Hemodialysis ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Clinical Manifestations of Cardiac Disease in Patients with End Stage Renal Disease Under Maintenance Hemodialysis in a Tertiary Level Hospital of Nepal

2016 ◽  
Vol 15 (1) ◽  
pp. 61-65
Author(s):  
Kumar Roka ◽  
Pratibha Bista Roka
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Low Voltage ◽  
Clinical Manifestations ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Maintenance Hemodialysis ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

Introduction: End stage renal disease presents with multiple clinical and systemic manifestations. The aim of the present study was to identify the early cardiac and other morbidities in end stage renal disease (ESRD) patients who were under maintenance hemodialysis.Methods: This was an observational, prospective study conducted in fifty established ESRD patients of 20 to 74 years under maintenance hemodialysis in Nephrology unit of Shree Birendra Hospital. Clinical examination, laboratory parameters, electrocardiogram and echocardiography findings were used to identify the morbidities. Results: Among all patients enrolled in the study 88.7% had anemia, 64.2 % systolic murmurs, 62.26 % pedal edema, 73.6 % fatiguability, 71.7 % angina, 24.4 % palpitations and 13.2 % had breathlessness on exertion.  62.26% of the patients had hypertension and 13.20 % had diabetes. In the electrocardiogram, prolonged QTc was observed in 10.4%, followed by T wave inversion in 9.4 % and finally low voltage complex comprised 7.6 %. The echocardiogram showed left ventricular diastolic dysfunction in 58.5 %, left ventricular hypertrophy (overall type) 49 % and valvular lesion like mitral regurgitation and tricuspid regurgitation 83 % and 58.5 % respectively. Conclusion: Cardiac co-morbidities are common in patients diagnosed with ESRD on maintenance hemodialysis.

Sign in / Sign up

Export Citation Format

Share Document