scholarly journals Variability in urinary biomarkers of human exposure to polycyclic aromatic hydrocarbons and its association with oxidative stress

2021 ◽  
Vol 156 ◽  
pp. 106720
Author(s):  
Hongkai Zhu ◽  
Maria-Pilar Martinez-Moral ◽  
Kurunthachalam Kannan
2017 ◽  
Vol 228 ◽  
pp. 311-320 ◽  
Author(s):  
Nesta Bortey-Sam ◽  
Yoshinori Ikenaka ◽  
Osei Akoto ◽  
Shouta M.M. Nakayama ◽  
Kwadwo A. Asante ◽  
...  

Epidemiology ◽  
2004 ◽  
Vol 15 (4) ◽  
pp. S75
Author(s):  
Zheng (Jane) Li ◽  
Lovisa C.S. Romanoff ◽  
Kisha J. Young ◽  
Nelson C. Blakely ◽  
Raymond Wei ◽  
...  

Author(s):  
Marta Oliveira ◽  
Sílvia Capelas ◽  
Cristina Delerue-Matos ◽  
Simone Morais

Grilling activities release large amounts of hazardous pollutants, but information on restaurant grill workers’ exposure to polycyclic aromatic hydrocarbons (PAHs) is almost inexistent. This study assessed the impact of grilling emissions on total workers’ exposure to PAHs by evaluating the concentrations of six urinary biomarkers of exposure (OHPAHs): naphthalene, acenaphthene, fluorene, phenanthrene, pyrene, and benzo(a)pyrene. Individual levels and excretion profiles of urinary OHPAHs were determined during working and nonworking periods. Urinary OHPAHs were quantified by high-performance liquid-chromatography with fluorescence detection. Levels of total OHPAHs (∑OHPAHs) were significantly increased (about nine times; p ≤ 0.001) during working comparatively with nonworking days. Urinary 1-hydroxynaphthalene + 1-hydroxyacenapthene and 2-hydroxyfluorene presented the highest increments (ca. 23- and 6-fold increase, respectively), followed by 1-hydroxyphenanthrene (ca. 2.3 times) and 1-hydroxypyrene (ca. 1.8 times). Additionally, 1-hydroxypyrene levels were higher than the benchmark, 0.5 µmol/mol creatinine, in 5% of exposed workers. Moreover, 3-hydroxybenzo(a)pyrene, biomarker of exposure to carcinogenic PAHs, was detected in 13% of exposed workers. Individual excretion profiles showed a cumulative increase in ∑OHPAHs during consecutive working days. A principal component analysis model partially discriminated workers’ exposure during working and nonworking periods showing the impact of grilling activities. Urinary OHPAHs were increased in grill workers during working days.


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