Unraveling the toxic effects of neonicotinoid insecticides on the thyroid endocrine system of lizards

2020 ◽  
Vol 258 ◽  
pp. 113731 ◽  
Author(s):  
Yinghuan Wang ◽  
Peng Xu ◽  
Jing Chang ◽  
Wei Li ◽  
Lu Yang ◽  
...  
Keyword(s):  
Endocrine System ◽  
Toxic Effects ◽  
Neonicotinoid Insecticides

Analgesic and Toxic Effects of Neonicotinoid Insecticides in Mice

2001 ◽  
Vol 177 (1) ◽  
pp. 77-83 ◽  
Author(s):  
Motohiro Tomizawa ◽  
Alan Cowan ◽  
John E. Casida
Keyword(s):  
Toxic Effects ◽  
Neonicotinoid Insecticides

scholarly journals Triclosan in Toothpaste, Is There Any Real Risk for the Health?

2016 ◽  
Vol 18 (2) ◽  
pp. 41
Author(s):  
Gabriela García C.D. ◽  
Alejandra Sánchez C.D., M.C. ◽  
Edith Galindo C.D., M.C., PhD. ◽  
Bernardino Cerda C.D., M.C., PhD.
Keyword(s):  
Public Opinion ◽  
State Of The Art ◽  
Endocrine System ◽  
The State ◽  
Toxic Action ◽  
Toxic Effects ◽  
Cellular Mechanisms ◽  
Real Risk

Triclosan is an antimicrobial drug that is widely used in products for human hygiene, beauty and home cleanliness. It is a common compound in toothpaste that have showed efficacy on the control and treatment of gingivitis. However, during the last decade, the triclosan has been extensively investigated because of its cytotoxicity, its ability to disturb cellular mechanisms on endocrine-system cells, and because of its cancerogenic in vitro and in vivo properties. Moreover, public opinion has paid attention to the toxic action of the triclosan. Thus, the dentist should know the state of the art about the detrimental effects of triclosan on patients’ health. This review explores the triclosan on its cytotoxicity, in vitro and in vivo cancerogenic effects, absorption in humans, and the toxic effects caused by triclosan toothpaste.

An Overview of Endocrine Modulators

1998 ◽  
Vol 17 (2) ◽  
pp. 105-110 ◽  
Author(s):  
Daniel M. Byrd ◽  
William H. Benson ◽  
Keith R. Solomon ◽  
John A. Thomas ◽  
William J. Waddell
Keyword(s):  
Adverse Effects ◽  
Human Health ◽  
Health Effects ◽  
Scientific Information ◽  
Endocrine System ◽  
Toxic Effects ◽  
System 2 ◽  
Valley Forge ◽  
Human Health Effects ◽  
Endocrine Modulation

During the American College of Toxicology's Symposium on Endocrine Modulators (Valley Forge, PA, November 1996), the speakers evaluated relevant scientific information and discussed three general ideas, as follows: (1) The available epidem iological data are inconsistent with significant increases in observed human health effects that might relate to the modulation of the endocrine system. (2) Environm ental contarn in ants have produced toxic effects in wildlife at specific locations. In select instances, the adverse effects observed may involve modulation of endocrine pathways. (3) Additional research focused on endocrine modulation is desirable in order to address this issue within a sound, scientificframework.

scholarly journals Influence of pyrethroid and neonicotinoid insecticides on lizards (Reptilia, Squamata) (a review)

2021 ◽  
Vol 50 ◽  
pp. 81-90
Author(s):  
S. V. Yermolenko ◽  
V. Y. Gasso ◽  
V. A. Spirina ◽  
A. O. Huslystyi
Keyword(s):  
Economic Activity ◽  
Environmental Risks ◽  
Toxic Effects ◽  
Laboratory Studies ◽  
Neonicotinoid Insecticides ◽  
Research Activities ◽  
Toxic Metabolites ◽  
Animal Populations ◽  
Neonicotinoid Pesticides ◽  
Over Time

Pyrethroid and neonicotinoid pesticides are synthetic substances that are distributed in different economic activity spheres and until recent times were considered one of the safe types of insecticides. It is known that the use of pyrethroid and neonicotinoid insecticides have certain environmental risks for animal populations. Reptiles manifest a significant sensitivity to this family of insecticides. Lizards (Lacertilia) is a numerous group of animals, a large number of species of which is associated with biotopes located in the landscapes influenced by pesticides. Features of toxic effects of pyrethroid and neonicotinoid insecticides are investigated on a small number of Lacertilia species and mainly on small lizards. An analysis of previous studies allowed identifying certain features of the toxic effect of pyrethroids and neonicotinoids on the lizards. Affecting this group of insecticides in lizards may increase mortality and neurological deviations, whose symptoms may reduce over time. Laboratory studies indicate that these substances can lead to increased lizard lethality and to hormonal, biochemical, and neuralgic deviations. The conducted studies indicate that these insecticides have an antiandrogenic effect that may decrease the reproductive success of lizards. The metabolism of insecticides in the lizard organism causes the formation of toxic metabolites, which may be accompanied by a greater poisoning of the lizard body than detoxification. Enantiomers of the investigated insecticides, exhibit a different degree of toxicity. A number of parameters of toxic effects are proposed as biomarkers of intoxication with pyrethroid and neonicotinoid insecticides. Lizards can be used for bioindication of synthetic insecticides, but the research activities on this issue began to grow in recent decades.

scholarly journals Toxic Effects of Neonicotinoid Insecticides on a Field Strain of Cotton Leafworm, Spodoptera littoralis

2018 ◽  
Vol 11 (4) ◽  
pp. 179-185 ◽  
Author(s):  
El-Sayed Abdel-Malek El-Sheikh ◽  
Marwa Ali El-Saleh ◽  
Ali Ahmed Aioub ◽  
Wahied Mahmoud Desuky
Keyword(s):  
Spodoptera Littoralis ◽  
Field Strain ◽  
Toxic Effects ◽  
Cotton Leafworm ◽  
Neonicotinoid Insecticides

scholarly journals Triclosan in Toothpaste, Is There Any Real Risk for the Health?

2016 ◽  
Vol 18 (2) ◽  
pp. 41
Author(s):  
Gabriela García C.D. ◽  
Alejandra Sánchez C.D., M.C. ◽  
Edith Galindo C.D., M.C., PhD. ◽  
Bernardino Cerda C.D., M.C., PhD.
Keyword(s):  
Public Opinion ◽  
State Of The Art ◽  
Endocrine System ◽  
The State ◽  
Toxic Action ◽  
Toxic Effects ◽  
Cellular Mechanisms ◽  
Real Risk

Triclosan is an antimicrobial drug that is widely used in products for human hygiene, beauty and home cleanliness. It is a common compound in toothpaste that have showed efficacy on the control and treatment of gingivitis. However, during the last decade, the triclosan has been extensively investigated because of its cytotoxicity, its ability to disturb cellular mechanisms on endocrine-system cells, and because of its cancerogenic in vitro and in vivo properties. Moreover, public opinion has paid attention to the toxic action of the triclosan. Thus, the dentist should know the state of the art about the detrimental effects of triclosan on patients’ health. This review explores the triclosan on its cytotoxicity, in vitro and in vivo cancerogenic effects, absorption in humans, and the toxic effects caused by triclosan toothpaste.

Ultrastructure of the effect of T-514 obtained from Karwinskia humboldtiana on assembly and integrity of yeast's peroxisomes

1991 ◽  
Vol 49 ◽  
pp. 136-137
Author(s):  
J. Sepulveda-Saavedra ◽  
I. Vander-Klei ◽  
M. Venhuis ◽  
Y. Piñeyro-Lopez
Keyword(s):  
Culture Conditions ◽  
Toxic Effects ◽  
Candida Boidinii ◽  
Central Mexico ◽  
Poisonous Plant ◽  
Biological Behaviour ◽  
Enzyme Content ◽  
Fat Deposits ◽  
Yeast Model

Karwinskia humboldtiana is a poisonous plant that grows in semi desertic areas in north and central México. It produces several substances with different toxic effects. One of them designated T-514 damages severely the lung, kidney and liver, producing in the hepatoeyte large intracellular fat deposits and necrosis. Preliminary observations demonstrated that three is a decrease in the amount of peroxisomes in the hepatocytes of experimentally intoxicated rats and monkeys. To study the effect exerted by the T-514 on peroxisomes, a yeast model was selected, thus, three species: Saccha romices cerevisiae, Ilansenula polymorpha and Candida boidinii were used, because there is information concerning their peroxisome's morphology, enzyme content, biological behaviour under different culture conditions and biogenesis.

Some Conditions Necessary for Pinocytosis

1968 ◽  
Vol 26 ◽  
pp. 142-143
Author(s):  
M. W. Brightman
Keyword(s):  
Smooth Muscle ◽  
Cell Membrane ◽  
Toxic Effects ◽  
Cytological Evidence ◽  
Cell Processes

The cytological evidence for pinocytosis is the focal infolding of the cell membrane to form surface pits that eventually pinch off and move into the cytoplasm. This activity, which can be inhibited by oxidative and glycolytic poisons, is performed only by cell processes that are at least 300A wide. However, the interpretation of such toxic effects becomes equivocal if the membrane invaginations do not normally lead to the formation of migratory vesicles, as in some endothelia and in smooth muscle. The present study is an attempt to set forth some conditions under which pinocytosis, as distinct from the mere inclusion of material in surface invaginations, can take place.

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