Using Machine Learning To Build Individualized Prediction Models Of Future Quality Of Life In Psychosis Patients

2017 ◽  
Vol 27 ◽  
pp. S464
Author(s):  
Janos Kalman ◽  
Monika Budde ◽  
Dominic Dwyer ◽  
Sergi Papiol ◽  
Heike Anderson-Schmidt ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Machine Learning ◽  
Prediction Models ◽  
Individualized Prediction

The PSYchiatric Clinical Outcome Prediction (PSYCOP) cohort: Leveraging the potential of electronic health records in the treatment of mental disorders

2021 ◽  
pp. 1-27
Author(s):  
Lasse Hansen ◽  
Kenneth C. Enevoldsen ◽  
Martin Bernstorff ◽  
Kristoffer L. Nielbo ◽  
Andreas A. Danielsen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Machine Learning ◽  
Mental Illness ◽  
Clinical Outcome ◽  
Outcome Prediction ◽  
Prediction Models ◽  
Health Records ◽  
Machine Learning Methods ◽  
Clinical Outcome Prediction

Abstract Background The quality of life and lifespan are greatly reduced among individuals with mental illness. To improve prognosis, the nascent field of precision psychiatry aims to provide personalized predictions for the course of illness and response to treatment. Unfortunately, the results of precision psychiatry studies are rarely externally validated, almost never implemented in clinical practice, and tend to focus on a few selected outcomes. To overcome these challenges, we have established the PSYchiatric Clinical Outcome Prediction (PSYCOP) cohort, which will form the basis for extensive studies in the upcoming years. Methods PSYCOP is a retrospective cohort study that includes all patients with at least one contact with the psychiatric services of the Central Denmark Region in the period from January 1, 2011 to October 28, 2020 (n=119,291). All data from the electronic health records (EHR) are included, spanning diagnoses, information on treatments, clinical notes, discharge summaries, laboratory tests etc. Based on these data, machine learning methods will be used to make prediction models for a range of clinical outcomes, such as diagnostic shifts, treatment response, medical comorbidity, and premature mortality, with an explicit focus on clinical feasibility and implementation. Discussion We expect that studies based on the PSYCOP cohort will advance the field of precision psychiatry through the use of state-of-the-art machine learning methods on a large and representative dataset. Implementation of prediction models in clinical psychiatry will likely improve treatment and, hopefully, increase the quality of life and lifespan of those with mental illness.

scholarly journals Analysis of ergonomic and unergonomic human lifting behaviors by using Inertial Measurement Units

2017 ◽  
Vol 3 (1) ◽  
pp. 7-10 ◽  
Author(s):  
Jan Kuschan ◽  
Henning Schmidt ◽  
Jörg Krüger
Keyword(s):  
Quality Of Life ◽  
Machine Learning ◽  
Angular Velocity ◽  
Musculoskeletal System ◽  
Occupational Diseases ◽  
Inertial Measurement Units ◽  
Inertial Measurement ◽  
Measurement Units ◽  
Main Components

Abstract:This paper presents an analysis of two distinct human lifting movements regarding acceleration and angular velocity. For the first movement, the ergonomic one, the test persons produced the lifting power by squatting down, bending at the hips and knees only. Whereas performing the unergonomic one they bent forward lifting the box mainly with their backs. The measurements were taken by using a vest equipped with five Inertial Measurement Units (IMU) with 9 Dimensions of Freedom (DOF) each. In the following the IMU data captured for these two movements will be evaluated using statistics and visualized. It will also be discussed with respect to their suitability as features for further machine learning classifications. The reason for observing these movements is that occupational diseases of the musculoskeletal system lead to a reduction of the workers’ quality of life and extra costs for companies. Therefore, a vest, called CareJack, was designed to give the worker a real-time feedback about his ergonomic state while working. The CareJack is an approach to reduce the risk of spinal and back diseases. This paper will also present the idea behind it as well as its main components.

Reviewing the use and quality of machine learning in developing clinical prediction models for cardiovascular disease

2021 ◽  
pp. postgradmedj-2020-139352
Author(s):  
Simon Allan ◽  
Raphael Olaiya ◽  
Rasan Burhan
Keyword(s):  
Machine Learning ◽  
Cardiovascular Disease ◽  
Prediction Models ◽  
Bone Fractures ◽  
Statin Treatment ◽  
Computer Algorithms ◽  
Clinical Prediction ◽  
Clinical Prediction Models ◽  
Heart Attacks

Cardiovascular disease (CVD) is one of the leading causes of death across the world. CVD can lead to angina, heart attacks, heart failure, strokes, and eventually, death; among many other serious conditions. The early intervention with those at a higher risk of developing CVD, typically with statin treatment, leads to better health outcomes. For this reason, clinical prediction models (CPMs) have been developed to identify those at a high risk of developing CVD so that treatment can begin at an earlier stage. Currently, CPMs are built around statistical analysis of factors linked to developing CVD, such as body mass index and family history. The emerging field of machine learning (ML) in healthcare, using computer algorithms that learn from a dataset without explicit programming, has the potential to outperform the CPMs available today. ML has already shown exciting progress in the detection of skin malignancies, bone fractures and many other medical conditions. In this review, we will analyse and explain the CPMs currently in use with comparisons to their developing ML counterparts. We have found that although the newest non-ML CPMs are effective, ML-based approaches consistently outperform them. However, improvements to the literature need to be made before ML should be implemented over current CPMs.

scholarly journals Machine-Learning Points at Endoscopic, Quality of Life, and Olfactory Parameters as Outcome Criteria for Endoscopic Paranasal Sinus Surgery in Chronic Rhinosinusitis

2021 ◽  
Vol 10 (18) ◽  
pp. 4245
Author(s):  
Jörn Lötsch ◽  
Constantin A. Hintschich ◽  
Petros Petridis ◽  
Jürgen Pade ◽  
Thomas Hummel
Keyword(s):  
Quality Of Life ◽  
Machine Learning ◽  
Chronic Rhinosinusitis ◽  
Paranasal Sinus ◽  
Endoscopic Sinus Surgery ◽  
Relevant Information ◽  
Olfactory Function ◽  
Sinus Surgery ◽  
Paranasal Sinus Surgery

Chronic rhinosinusitis (CRS) is often treated by functional endoscopic paranasal sinus surgery, which improves endoscopic parameters and quality of life, while olfactory function was suggested as a further criterion of treatment success. In a prospective cohort study, 37 parameters from four categories were recorded from 60 men and 98 women before and four months after endoscopic sinus surgery, including endoscopic measures of nasal anatomy/pathology, assessments of olfactory function, quality of life, and socio-demographic or concomitant conditions. Parameters containing relevant information about changes associated with surgery were examined using unsupervised and supervised methods, including machine-learning techniques for feature selection. The analyzed cohort included 52 men and 38 women. Changes in the endoscopic Lildholdt score allowed separation of baseline from postoperative data with a cross-validated accuracy of 85%. Further relevant information included primary nasal symptoms from SNOT-20 assessments, and self-assessments of olfactory function. Overall improvement in these relevant parameters was observed in 95% of patients. A ranked list of criteria was developed as a proposal to assess the outcome of functional endoscopic sinus surgery in CRS patients with nasal polyposis. Three different facets were captured, including the Lildholdt score as an endoscopic measure and, in addition, disease-specific quality of life and subjectively perceived olfactory function.

scholarly journals Combine Clustering and Machine Learning for Enhancing the Efficiency of Energy Baseline of Chiller System

Energies ◽  
2020 ◽  
Vol 13 (17) ◽  
pp. 4368 ◽  
Author(s):  
Chun-Wei Chen ◽  
Chun-Chang Li ◽  
Chen-Yu Lin
Keyword(s):  
Machine Learning ◽  
Prediction Accuracy ◽  
Prediction Models ◽  
Machine Learning Algorithms ◽  
Learning Models ◽  
Important Method ◽  
Gap Statistic ◽  
Machine Learning Model ◽  
Key Variables

Energy baseline is an important method for measuring the energy-saving benefits of chiller system, and the benefits can be calculated by comparing prediction models and actual results. Currently, machine learning is often adopted as a prediction model for energy baselines. Common models include regression, ensemble learning, and deep learning models. In this study, we first reviewed several machine learning algorithms, which were used to establish prediction models. Then, the concept of clustering to preprocess chiller data was adopted. Data mining, K-means clustering, and gap statistic were used to successfully identify the critical variables to cluster chiller modes. Applying these key variables effectively enhanced the quality of the chiller data, and combining the clustering results and the machine learning model effectively improved the prediction accuracy of the model and the reliability of the energy baselines.

Sign in / Sign up

Export Citation Format

Share Document