Prescribing practices in psychiatric hospitals in Eastern Europe

2011 ◽  
Vol 26 (7) ◽  
pp. 414-418 ◽  
Author(s):  
V. Jordanova ◽  
N.P. Maric ◽  
V. Alikaj ◽  
M. Bajs ◽  
T. Cavic ◽  
...  
Keyword(s):  
Eastern Europe ◽  
Western Europe ◽  
Atypical Antipsychotics ◽  
Psychiatric Care ◽  
Anticholinergic Drug ◽  
Psychiatric Hospitals ◽  
Evidence Based ◽  
Prescribing Practices ◽  
The Mean ◽  
Clinical Records

AbstractBackgroundThere has been no evidence about the prescribing practices in psychiatric care in Eastern Europe.AimsTo examine the patterns of psychotropic prescribing in five countries of Eastern Europe.MethodWe conducted a one-day census of psychiatric treatments used in eight psychiatric hospitals in Albania, Croatia, Macedonia, Serbia and Romania. We examined clinical records and medication charts of 1304 patients.ResultsThe use of polypharmacy was frequent across all diagnostic groups. Only 6.8% of patients were on monotherapy. The mean number of prescribed drugs was 2.8 (SD 0.97) with 26.5% receiving two drugs, 42.1% receiving three drugs and 22.1% being prescribed four or more psychotropic drugs. Typical antipsychotics were prescribed to 63% and atypical antipsychotics to 40% of patients with psychosis. Older generations of antidepressants were prescribed to 29% of patients with depression. Anxiolitic drugs were prescribed to 20.4% and benzodiazepines to 68.5% of patients. One third of patients received an anticholinergic drug on a regular basis.ConclusionsOlder generation antipsychotics and antidepressants were used more frequently than in the countries of Western Europe. Psychotropic polypharmacy is a common practice. There is a need for adopting more evidence-based practice in psychiatric care in these countries.

scholarly journals Comparison and evaluation of modelled and GOME measurement derived tropospheric NO<sub>2</sub> columns over Western and Eastern Europe

2005 ◽  
Vol 5 (1) ◽  
pp. 169-190 ◽  
Author(s):  
I. B. Konovalov ◽  
M. Beekmann ◽  
R. Vautard ◽  
J. P. Burrows ◽  
A. Richter ◽  
...  
Keyword(s):  
Eastern Europe ◽  
Western Europe ◽  
Transport Model ◽  
Simulated Data ◽  
Horizontal Resolution ◽  
Random Errors ◽  
Multiplicative Character ◽  
Continental Scale ◽  
Tropospheric No2 ◽  
The Mean

Abstract. We present the results of a first comparison of the tropospheric NO2 column amounts derived from the measurements of the Global Ozone Monitoring Experiment (GOME) with the simulated data from a European scale chemistry transport model (CTM) which is distinct from existing global scale CTMs in higher horizontal resolution and more detailed description of the boundary layer processes and emissions. We employ, on the one hand, the newly developed extended version of the CHIMERE CTM, which covers both Western and Eastern Europe, and, on the other hand, the most recent version (Version 2) of GOME measurement based data-products, developed at the University of Bremen. We evaluate our model with the data from ground based monitoring of ozone and verify that it has a sufficiently high level of performance, which is expected for a state-of-the-art continental scale CTM. The major focus of the study is on a systematic statistical analysis and a comparison of spatial variability of the tropospheric NO2 columns simulated with CHIMERE and derived from GOME measurements. The analysis is performed separately for Western and Eastern Europe using the data for summer months of 1997 and 2001. In this way, we obtain useful information on the nature and magnitudes of uncertainties of spatial distributions of the considered data. Specifically, for Western Europe, it is found that the uncertainties of NO2 columns from GOME and CHIMERE are predominantly of the multiplicative character, and that the mean relative random (multiplicative) errors of the GOME measurement derived and simulated data averaged over the summer seasons considered do not exceed 23% and 32%, respectively. The mean absolute (additive) errors of both kinds of the data are estimated to be less than 3x1014mol/cm2. In Eastern Europe, the uncertainties have more complex character, and the separation between their multiplicative and additive parts is not sufficiently unambiguous. It is found, however, that the total random errors of NO2 columns from both GOME and CHIMERE over Eastern Europe are not, on the average, larger than the errors of the NO2 columns with similar magnitudes over Western Europe.

scholarly journals Comparison and evaluation of modelled and GOME measurement derived tropospheric NO<sub>2</sub> columns over Western and Eastern Europe

2004 ◽  
Vol 4 (5) ◽  
pp. 6503-6558 ◽  
Author(s):  
I. B. Konovalov ◽  
M. Beekmann ◽  
R. Vautard ◽  
J. P. Burrows ◽  
A. Richter ◽  
...  
Keyword(s):  
Eastern Europe ◽  
Western Europe ◽  
Transport Model ◽  
Simulated Data ◽  
Horizontal Resolution ◽  
Random Errors ◽  
Continental Scale ◽  
Upper Limits ◽  
Tropospheric No2 ◽  
The Mean

Abstract. We present the results of a first comparison of the tropospheric NO2 column amounts derived from the measurements of the Global Ozone Monitoring Experiment (GOME) with the simulated data from a European scale chemistry transport model (CTM) which is distinctive from existing global scale CTMs in higher horizontal resolution and more detailed description of the boundary layer processes and emissions. We employ, on the one hand, the newly developed extended version of the CHIMERE CTM, which covers both Western and Eastern Europe, and, on the other hand, the most recent version (Version 2) of GOME measurement based data-products, developed at the University of Bremen. We evaluate our model with the data of ground based monitoring of ozone and verify that it has a sufficiently high level of performance, which is expected for a state-of-the-art continental scale CTM. The major focus of the study is on a systematic statistical analysis and a comparison of spatial variability of the tropospheric NO2 columns simulated with CHIMERE and derived from GOME measurements. The analysis is performed separately for Western and Eastern Europe using the data for summer months of 1997 and 2001. In this way, we evaluate the upper limits to uncertainties of spatial distributions of the considered data. Specifically, for Western Europe, it is found that the mean relative (multiplicative) random errors of the GOME measurement derived and simulated data averaged over the summer seasons considered do not exceed 25% and 35%, respectively, and the mean absolute (additive) errors are less than 3·1014 mol/cm2. The upper limits for the multiplicative errors for Eastern Europe are shown to be smaller than those for Western Europe and do not exceed 15% and 24% for NO2 columns from GOME and CHIMERE, respectively. The relative contribution of the additive errors is found to be much larger for Eastern Europe, but their mean absolute values are less than 2·1014 mol/cm2.

scholarly journals Tackling myths of common prescribing patterns in schizophrenia amongst Egyptian psychiatrists

2020 ◽  
Vol 27 (1) ◽  
Author(s):  
Samir Abolmagd ◽  
Dina Aly El-Gabry ◽  
Hussien Elkholy ◽  
Karim Abdel Aziz
Keyword(s):  
Atypical Antipsychotics ◽  
Treatment Guidelines ◽  
Mood Stabilizer ◽  
Prescribing Patterns ◽  
Anticholinergic Medication ◽  
Evidence Based ◽  
Prescribing Practices ◽  
Cross Sectional Survey ◽  
Related Factors ◽  
Antipsychotic Prescribing

Abstract Background There is limited data related to how psychiatrists actually choose amongst different medications, especially in Egypt. Our aim was to survey a sample of psychiatrists regarding common patterns of antipsychotic prescribing practices and review how these vary from the evidence-based. We conducted a qualitative, cross-sectional survey of 124 psychiatrists of different grades from hospitals across Cairo, Egypt. Questions were asked to elicit attitudes towards common antipsychotic prescribing practices and the use of treatment guidelines in schizophrenia. Results A total 77.4% participants said they would prescribe atypical antipsychotics as first-line treatment if cost were not an issue, 42.7% said they commonly add anticholinergics from the start with antipsychotics, 50% said they would maintain patients on anticholinergics for as long as they were receiving antipsychotics, 93.5% said they commonly or in some situations combine typical depot antipsychotics with oral atypical antipsychotics, 88.7% said they commonly or in some situations use antipsychotics in small doses for sedation, and 55.6% sometimes add a mood stabilizer to enhance the effect of antipsychotic drugs. Using logistic regression, physician grade significantly predicted whether participants commonly add anticholinergic medication from the start with antipsychotics (p = 0.001). Age and gender significantly predicted whether participants sometimes add a mood stabilizer to enhance the effect of antipsychotics (p < 0.05). Conclusions We demonstrated that several antipsychotic prescribing practices were not evidence-based, yet appeared to be prevalent in a large proportion of participants. A number of demographic and psychiatrist-related factors predicted certain prescribing patterns.

scholarly journals Introduction: The economic and social aspects of the family life-cycle in traditional and modern Japan

2000 ◽  
Vol 15 (1) ◽  
pp. 11-15 ◽  
Author(s):  
OSAMU SAITO
Keyword(s):  
Eastern Europe ◽  
Western Europe ◽  
Household Size ◽  
Low Fertility ◽  
Household Formation ◽  
Local Mode ◽  
Developmental Cycle ◽  
The Family ◽  
The Mean ◽  
The Individual

Since the publication of the seminal book of essays Household and family in past time in 1972, much research on the history of the family has concentrated on the situation in western and eastern Europe, and relied almost exclusively on census-type documents. It is, for example, established that whereas mean household size was small, the mean age at first marriage fairly high and neo-localism (the formation of an independent household on marriage) dominant in western Europe, almost the opposite applied in eastern Europe. Yet these findings do not preclude the possibility of discovering regions where in statistical terms the mean household size was not large and the proportion of complex households not particularly high, but where the neo-local mode of household formation was not the norm. Such a region could have a preference for joint families (two or more married sons co-residing with their father) with a low-fertility demographic regime, or stem families (one co-residing married son) with that of intermediate to low fertility.Traditional Japan is an example of just such a stem-family society. There the household, not the individual, was perceived as the basic social and legal unit of society. This unit was called ie and its headship, authority and property were expected to be handed down from the father to a particular son, enabling the household to follow alternating stages of ‘simple’, ‘multiple’ and ‘extended’ forms over the developmental cycle, more or less in accordance with the predictions of Lutz Berkner. As articles in the section of Laslett and Wall's Household and family on Japan have already shown, the mean household size in eighteenth- and nineteenth-century Japan was not higher than that in England, but the mean age at marriage was lower than in the English population. Moreover, household formation and succession rules under the Japanese ie system were not compatible with the simple family mode.

From Black Death to Black Hole

2018 ◽  
Author(s):  
Marcin Piatkowski
Keyword(s):  
Economic Development ◽  
Black Hole ◽  
Sixteenth Century ◽  
Eastern Europe ◽  
Rule Of Law ◽  
Western Europe ◽  
Black Death ◽  
European Continent ◽  
The Past

In this chapter I explain why Poland and most countries in Eastern Europe have always lagged behind Western Europe in economic development. I discuss why in the past the European continent split into two parts and how Western and Eastern Europe followed starkly different developmental paths. I then demonstrate how Polish oligarchic elites built extractive institutions and how they adopted ideologies, cultures, and values, which undermined development from the late sixteenth century to 1939. I also describe how the elites created a libertarian country without taxes, state capacity, and rule of law, and how this ‘golden freedom’ led to Poland’s collapse and disappearance from the map of Europe in 1795. I argue that Polish extractive society was so well established that it could not reform itself from the inside. It was like a black hole, where the force of gravity is so strong that the light could not come out.

Conclusion

2017 ◽  
Author(s):  
Detlef Pollack ◽  
Gergely Rosta
Keyword(s):  
Eastern Europe ◽  
Western Europe ◽  
The Other ◽  
Market Model ◽  
Economic Prosperity ◽  
Economic Market ◽  
The Everyday ◽  
Economic Market Model ◽  
The One ◽  
Religious Landscape

The most important conclusions of this summarizing chapter are the following: The religious landscape of Eastern Europe is more diverse than that of Western Europe. The cases of Poland and the GDR confirm the hypothesis that there is a link between the diffusion of functions and the growth in the importance of religion. The strong processes of biographical individualization that occurred in the post-communist states did not necessarily intensify individual religiosity. The economic market model cannot be confirmed for Eastern Europe. There is in Eastern and Central Europe a demonstrable link between economic prosperity and the loosening of religious and church ties. What can act as a bulwark against the eroding effects of modernization is church activity on the one hand, and the everyday proximity, visibility, and concreteness of religious practices and rituals, symbols, images, and objects on the other.

The Puzzle of Populism

2017 ◽  
Author(s):  
Paul D. Kenny
Keyword(s):  
Latin America ◽  
Eastern Europe ◽  
Western Europe ◽  
Party Systems

This chapter sets out the puzzle at the center of the book: what explains the success of populist campaigners in India, Asia, and beyond? It summarizes the existing literature on populist success both in Latin America and Western Europe and argues that these explanations do a poor job of explaining Indian and Asian cases in particular. Populists win elections when the institutionalized ties between non-populist parties and voters decay. However, because different kinds of party systems experience distinct stresses and strains, we need different models of populist success based on the prevailing party­–voter linkage system in place in any given country. The chapter then sets out the rationale for concentrating on explaining populist success in patronage-based party systems, which are common not only to Asia, but also to Latin America and Eastern Europe.

scholarly journals Does age at aortic coarctation repair have an impact on left ventricle size and function?

2021 ◽  
Vol 22 (Supplement_1) ◽  
Author(s):  
S Cardoso Torres ◽  
CX Resende ◽  
PG Diogo ◽  
P Araujo ◽  
RA Pinto ◽  
...  
Keyword(s):  
Aortic Coarctation ◽  
Surgical Repair ◽  
Myocardial Dysfunction ◽  
Global Longitudinal Strain ◽  
Negative Relationship ◽  
Late Complications ◽  
Left Ventricular ◽  
Funding Sources ◽  
The Mean ◽  
Clinical Records

Abstract Funding Acknowledgements Type of funding sources: None. Introduction Adults with repaired aortic coarctation (CoA) require lifelong follow-up due to late complications, including left ventricular (LV) myocardial dysfunction. Age at the time of CoA repair is an important prognostic factor in these patients (pts). Purpose To evaluate LV size, ejection fraction (EF) and global longitudinal strain (GLS) values using 2D speckle tracking echocardiography (STE) in a population of adult pts with repaired CoA and to assess the relationship between these echocardiographic parameters and age at the time of CoA repair. Methods Retrospective analysis of adult pts with repaired CoA, followed in a Grown Up Congenital Heart Disease Centre. Pts with hemodynamically significant concomitant cardiac lesions were ruled out. Epidemiologic and clinical data were obtained from clinical records. Transthoracic echocardiograms were reviewed in order to assess GLS using 2DSTE (Echopac Software, GE). Results The study population consisted of 63 pts (61.9% male), with a mean age of 35.3 years at the time of the echocardiographic evaluation. The mean age at the time of the CoA repair was 117 months (95% CI 89.8-144.1 months). Surgical repair was performed in 46 pts (73%): resection with subclavian artery flap aortoplasty (n = 21); patch aortoplasty (n = 15) and head-to-head anastomosis (n = 10). In 10 pts there was no data regarding the type of surgical repair. Seven pts (11.1%) were submitted to percutaneous intervention (6 with aortic stent implantation and 1 with balloon aortic angioplasty). Mean LVEF was 63.4% (CI 95% 55.6 – 71.2%) and mean LV end-diastolic diameter (LVEDD) was 50mm (CI 95% 43-57mm). Mean GLS was - 17.3 (CI 95% 14.8- 19.8), which is inferior to the mean normal values reported for the software used. Age at the time of CoA repair had a statistically significant positive linear relationship with LVEDD (r= 0.282; p= 0.026) and a linear negative relationship with both GLS (r= -0,29; p= 0.022) and LVEF (r= -0.33; p= 0.05). Conclusion Older age at the time of CoA repair was associated with increased LVEDD and decreased GLS and LVEF. Also, GLS may be an important tool for the identification of subclinical LV dysfunction in adult pts with repaired CoA.

scholarly journals Incidence and Characteristics of Retinoblastoma in Poland: The First Nationwide Study 2010–2017

2021 ◽  
Vol 18 (12) ◽  
pp. 6539
Author(s):  
Michał S. Nowak ◽  
Bożena Romanowska-Dixon ◽  
Iwona Grabska-Liberek ◽  
Michał Żurek
Keyword(s):  
Western Europe ◽  
External Beam Radiotherapy ◽  
Cohort Analysis ◽  
Developed Countries ◽  
Live Births ◽  
Focal Treatment ◽  
Different Types ◽  
The Mean ◽  
Birth Cohort Analysis

Background: The present study aimed to investigate the incidence and characteristics of retinoblastoma in the overall population of Poland. Methods: The retrospective survey of both National Health Fund (NHF) and National Cancer Registry (NCR) databases were performed to identify all retinoblastoma cases in Poland in the years 2010–2017. Results: During 2010–2017, the mean age-standardised incidence of retinoblastoma (the unit of incidence is per 1,000,000 person-years) was 10.15 (95% CI 7.23–13.08) among children aged 0 to 4 years and 5.39 (95% CI 4.18–6.60) in those aged 0 to 9 years. During 2010–2014 (to allow 5 years of follow-up), the mean incidence of retinoblastoma by birth cohort analysis in Poland was 4.89 (95% CI 4.04–5.74) per 100,000 live births, corresponding to an incidence of 1 per 20,561 (95% CI 15,855–25,267) live births. In Poland, 14.6% of children with retinoblastoma had enucleation of the eye globe, 76.8% received different types of chemotherapy combined with focal treatment, 5.9% were treated with external beam radiotherapy, and 2.7% were treated with focal treatments only. Conclusions: The incidence of retinoblastoma and the pattern of medical management of retinoblastoma in Poland was similar to that reported in developed countries in Western Europe, Asia, and North America.

scholarly journals A systematic PRISMA review of individuals with autism spectrum disorder in secure psychiatric care: prevalence, treatment, risk assessment and other clinical considerations

2018 ◽  
Vol 8 (1) ◽  
pp. 58-79 ◽  
Author(s):  
Clare S. Allely
Keyword(s):  
Autism Spectrum Disorder ◽  
Psychiatric Care ◽  
Psychiatric Hospitals ◽  
Autistic Traits ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Bibliographic Databases ◽  
Future Research ◽  
Content Type ◽  
Secure Psychiatric Care

Purpose Patients with autism spectrum disorder (ASD) present with specific assessment, specific difficulties, needs and therapeutic issues and therefore are a challenging group for forensic services. Given the challenge that individuals with ASD present to forensic services, the suggested increase in the number of this group within this setting and the relatively little amount of research which suggests they face a number of difficulties within the prison environment, the purpose of this paper is to identify and review all the studies which have been carried out investigating any aspect of ASD in relation to secure hospital settings. Design/methodology/approach Seven internet-based bibliographic databases were used for the present review. The review followed the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines. Findings A total of 12 studies were included in this review; 3 looked at the prevalence of ASD in secure psychiatric hospitals. One study evaluated the clinical utility of the AQ screening tool to assess self-reported autistic traits in secure psychiatric settings. Three explored any type of characteristics of patients with ASD detained in secure psychiatric hospitals. One study investigated the experiences or quality of life of patients with an ASD detained in secure psychiatric care. Two studies investigated awareness, knowledge and/or views regarding patients with ASD held by staff working within secure psychiatric hospitals. Lastly, three studies (one of which was also included in the prevalence category above) looked at the effectiveness of interventions or treatment of patients with ASD in secure psychiatric hospitals. Clinical recommendations and future research directions are discussed. Originality/value To the author’s knowledge, this is the first review to explore what research has been carried out looking specifically at patients with ASD in relation to secure forensic settings.

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