Psychological and Psychophysiological Mechanisms of Mental Stress Reaction in Patients with ‘Hypertension at Work’, as Compared with ‘Classical’ Version of Essential Hypertension

2017 ◽  
Vol 41 (S1) ◽  
pp. S288-S288
Author(s):  
E. Pervichko ◽  
Y. Zinchenko ◽  
O. Ostroumova
Keyword(s):  
Essential Hypertension ◽  
State Anxiety ◽  
Mental Stress ◽  
Stress Reaction ◽  
Angiotensin I ◽  
Lower Growth ◽  
Induced Hypertension ◽  
Before And After ◽  
Response To Stress ◽  
Competing Interest

Introduction‘Hypertension at work’ today is found one of the most frequent forms of stress-induced hypertension.ObjectivesTo inquire into the specifics of psychological and psychophysiological mechanisms of stress reaction in patients with ‘hypertension at work’, as compared with ‘classical’ essential hypertension (EH).Materials and methodsThe study developed simulation of emotional stress with the aspiration level (AL) modeling. The level of state anxiety (SA), BP values, urine catecholamine levels and levels of renin and angiotonin I in blood plasma were taken before and after the experiment. Eighty-five patients with ‘hypertension at work’ (mean age was 45.9 ± 2.8) and 85 patients with ‘classical’ EH (mean age was 47.4 ± 4.5 years) took part in the study.ResultsRates of ‘hypertension at work’ patients, when compared with second group patients, revealed a significant increase (Р < 0.001) of systolic BP in response to stress loads (on average, for 16.1 ± 1.9 mmHg and 4.1 ± 0.7 mmHg, respectively). Initially ‘hypertension at work’ patients had significantly lower levels of catecholamines, than the second group, while the levels of renin and angiotensin I were comparable. During the experiment, the patients in the first group showed a significant decrease in all parameters. After the experiment, the patients with ‘HTN at work’ did not show increase of SA, but revealed more frequent inadequacy (69.4%) and instability (56.5%) on the AL. Patients with ‘classical’ EH more often demonstrate adequate AL and lower growth of BP after the experiment.ConclusionsPatients with ‘hypertension at work’ are more prone to repress their emotions. They reveal physiological features of chronic stress and psychophysiological exhaustion, if compared with second group patients.Disclosure of interestThe authors have not supplied their declaration of competing interest.

The Effect of Mental Stress on Catecholamines, their Metabolites and Plasma Renin Activity in Patients with Essential Hypertension and in Healthy Subjects

1979 ◽  
Vol 57 (s5) ◽  
pp. 229s-231s ◽  
Author(s):  
W. Januszewicz ◽  
M. Sznajderman ◽  
B. Wocial ◽  
T. Feltynowski ◽  
T. Klonowicz
Keyword(s):  
Essential Hypertension ◽  
Plasma Renin Activity ◽  
Urinary Excretion ◽  
Mental Stress ◽  
Healthy Subjects ◽  
Plasma Renin ◽  
Renin Activity ◽  
Vanillylmandelic Acid ◽  
Before And After ◽  
Noradrenaline And Adrenaline

1. Ten patients with essential hypertension and ten healthy men were submitted to mental stress consisting of Kraepelin's arithmetic test combined with noise. Concentrations of plasma and urine catecholamines and of their metabolites as well as plasma renin activity before and after the test were studied. 2. In both groups a significant increase of noradrenaline and adrenaline in blood and noradrenaline in urine was observed. The urinary excretion of dopamine fell significantly in both groups after stress. 3. After mental stress a significant increase in urinary excretion of 3-methoxy-4-hydroxyphenylglycol was observed in both groups. The excretion of vanillylmandelic acid decreased significantly only in healthy subjects. 4. The plasma renin activity rose significantly in both groups but the increase was more pronounced in healthy subjects.

Adrenoceptors on blood cells in patients with essential hypertension before and after mental stress

1989 ◽  
Vol 7 (7) ◽  
pp. 519-524 ◽  
Author(s):  
Sietze J. Graafsma ◽  
Lambertus J. van Tits ◽  
Petronella van Heijst ◽  
Joeke Reyenga ◽  
Jacques W M Lenders ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Blood Cells ◽  
Mental Stress ◽  
Before And After

scholarly journals Training vs. Competition in Sport: State Anxiety and Response of Stress Hormones in Young Swimmers

2021 ◽  
Vol 80 (1) ◽  
pp. 103-112
Author(s):  
Luis Carrasco Páez ◽  
Inmaculada C. Martínez-Díaz
Keyword(s):  
State Anxiety ◽  
Stress Hormones ◽  
National Level ◽  
Training Session ◽  
Physical Stress ◽  
Before And After ◽  
Assessment Time ◽  
Response To Stress ◽  
Significant Release ◽  
Regular Training

Abstract This study was aimed to assess the neuroendocrine response to stress induced by different sports environments (a regular training session and a competitive event), to define the contribution of psychological and physical stress, and to check the possible relationship between state-anxiety and stress hormones responses to competitive and non-competitive sports practices. Twelve young national-level male swimmers participated in this investigation. Endorphins, adrenocorticotropin, and prolactin plasma levels were measured at baseline conditions (t0), before a regular swimming training session (t1), and before and after real swimming competition consisting of 100 m freestyle (t2 and t3, respectively). Moreover, state-anxiety was evaluated in all assessment time-points. The results showed no differences in endorphin, adrenocorticotropin, prolactin and state-anxiety between t0 and t1; however, significant increases in endorphins (142%), prolactin (137%) and state-anxiety (13%) were observed in t2. Huge stress response was observed in t3 (increases of 354%, 387%, and 250% for endorphins, adrenocorticotropin, and prolactin, respectively) although state-anxiety decreased slightly. Lastly, a lack of the relationship between stress hormones and state-anxiety was found in all conditions. Mental and especially physical stress associated with sports competition induces a significant release of stress hormones which is not relevant for the regular training session.

The Effect of Mental Stress on Prostaglandin F2α in Patients with Essential Hypertension and in Healthy Subjects

1979 ◽  
Vol 57 (s5) ◽  
pp. 275s-277s ◽  
Author(s):  
H. Ignatowska-S̀witalska ◽  
T. Klonowicz ◽  
T. Feltynowski
Keyword(s):  
Essential Hypertension ◽  
Plasma Concentration ◽  
Urinary Excretion ◽  
Mental Stress ◽  
Healthy Subjects ◽  
Prostaglandin F2α ◽  
Urine Excretion ◽  
Hypertensive Patients ◽  
Response To Stress ◽  
The Individual

1. The influence of mental stress, 30 min Kraepelin's arithmetic test under noise on the plasma concentration and urinary excretion of prostaglandin (PG) F2α was studied in patients with essential hypertension and in healthy subjects. 2. Before the arithmetic test the plasma PGF2α in hypertensive patients was significantly higher than in healthy subjects. The mental stress produced a significant increase in plasma PGF2α in healthy subjects but not in patients with essential hypertension. 3. Three hour urine excretion of PGF2a before stress was about two times lower in hypertensive patients than in healthy subjects. After exposure to stress a significant decrease in urinary excretion of PGF2α was found in healthy subjects, but not in hypertensive patients. 4. The stress-induced increase in plasma PGF2α of healthy subjects may reflect elevated brain PGF2α synthesis. The individual differences in response to stress in hypertensive patients may result from specific impairments in synthesis and/or prostaglandin turnover.

A violation of emotion regulation as a central link in pathogenesis of stress-induced hypertension

2017 ◽  
Vol 41 (S1) ◽  
pp. S317-S317
Author(s):  
E. Pervichko ◽  
Y. Zinchenko ◽  
O. Ostroumova
Keyword(s):  
Emotion Regulation ◽  
Healthy Subjects ◽  
Emotion Dysregulation ◽  
Second Stage ◽  
New Meanings ◽  
Induced Hypertension ◽  
Before And After ◽  
Regulation Strategies ◽  
Competing Interest ◽  
System Today

IntroductionEssential hypertension (EH) is one of the most common diseases of the cardiovascular system. Today, scientists discover more and more patients whose BP values during work appear to be higher than those values during free time. This form of EH is called “hypertension at work”.ObjectiveTo study the role emotion dysregulation in the pathogenesis of EH.Materials and methodsA projective study of emotion regulation was undertaken with our modified version of Rosenzweig Picture-Frustration Test (Zinchernko, Pervichko). At the second stage of the study, the simulation of emotional stress with the aspiration level modelling was carried out. The level of state anxiety, BP values and levels of catecholamines, renin and angiotonin I were taken before and after the experiment. Eighty-five patients with “hypertension at work” (mean age: 45.9 ± 2.8), 85 patients with “classical” EH (mean age: 47.4 ± 4.5 years) and 82 healthy subjects (mean age: 44.9 ± 3.1) took part in the study.Results“Hypertension at work” patients significantly more frequently than patients from the second group and healthy subjects are more prone to rumination, disasterization and repression of their emotions. They will seldom employ the strategy of subjective-objective interactive transformations; their edibility to actualize new meanings in traumatic situations is diminished. We showed that emotion regulation strategies in “hypertension in the work” patients were ineffective in overcoming the emotional tension and created the conditions for chronization of high blood pressure, and could be considerded as the central link in pathogenesis of stress-induced hypertension.ConclusionThe results contributes to enrich our understanding of etiology and pathogenesis of EH.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Aerodynamic and Acoustic Voice Measures Before and After an Acute Public Speaking Stressor

2020 ◽  
Vol 63 (10) ◽  
pp. 3311-3325
Author(s):  
Brittany L. Perrine ◽  
Ronald C. Scherer
Keyword(s):  
Fundamental Frequency ◽  
Salivary Cortisol ◽  
Public Speaking ◽  
Stress System ◽  
Before And After ◽  
Subglottal Pressure ◽  
Response To Stress ◽  
System Activation ◽  
Speaking Fundamental Frequency ◽  
Pituitary Adrenal Axis

Purpose The goal of this study was to determine if differences in stress system activation lead to changes in speaking fundamental frequency, average oral airflow, and estimated subglottal pressure before and after an acute, psychosocial stressor. Method Eighteen vocally healthy adult females experienced the Trier Social Stress Test (TSST) to activate the hypothalamic–pituitary–adrenal axis. The TSST includes public speaking and performing mental arithmetic in front of an audience. At seven time points, three before the stressor and four after the stressor, the participants produced /pa/ repetitions, read the Rainbow Passage, and provided a saliva sample. Measures included (a) salivary cortisol level, (b) oral airflow, (c) estimated subglottal pressure, and (d) speaking fundamental frequency from the second sentence of the Rainbow Passage. Results Ten of the 18 participants experienced a hypothalamic–pituitary–adrenal axis response to stress as indicated by a 2.5-nmol/L increase in salivary cortisol from before the TSST to after the TSST. Those who experienced a response to stress had a significantly higher speaking fundamental frequency before and immediately after the stressor than later after the stressor. No other variable varied significantly due to the stressor. Conclusions This study suggests that the idiosyncratic and inconsistent voice changes reported in the literature may be explained by differences in stress system activation. In addition, laryngeal aerodynamic measures appear resilient to changes due to acute stress. Further work is needed to examine the influence of other stress systems and if these findings hold for dysphonic individuals.

Reduced latency to first antidepressant treatment in Italian patients with a more recent onset of major depressive disorder

2017 ◽  
Vol 41 (S1) ◽  
pp. S529-S529
Author(s):  
B. Grancini ◽  
B. Dell’Osso ◽  
L. Cremaschi ◽  
F. De Cagna ◽  
B. Benatti ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Antidepressant Treatment ◽  
Stressful Events ◽  
Major Depressive ◽  
Recent Onset ◽  
Valid Predictor ◽  
Before And After ◽  
Competing Interest ◽  
Year 2000

IntroductionMajor depressive disorder (MDD) is a prevalent burdensome disease, which frequently remains untreated. The duration of untreated illness (DUI) is modifiable parameter and a valid predictor of outcome. Previous investigation in patients with MDD revealed a DUI of different years, while recent reports have documented a reduction of DUI across time, in patients with different psychiatric disorders.Objectives/aimsThe present study was aimed to investigate potential differences in terms of DUI and related variables in patients with MDD across time.MethodsAn overall sample of 188 patients with MDD was divided in two subgroups on the basis of their epoch of onset (onset before and after year 2000). DUI and other onset-related variables were assessed through a specific questionnaire and compared between the two subgroups.ResultsThe whole sample showed a mean DUI of approximately 4.5 years, with a lower value in patients with more recent onset compared to the other subgroup (27.1 ± 42.6 vs. 75.8 ± 105.2 months, P < .05). Moreover, patients with onset after 2000 reported higher rates of onset-related stressful events and lower ones for benzodiazepines prescription (65% vs. 81%; P = 0.02; 47% vs. 30%; P = 0.02).ConclusionsThe comparison of groups with different epochs of onset showed a significant reduction in terms of DUI and benzodiazepines prescription, and a higher rate of onset-related stressful events in patients with a more recent onset. Reported findings are of epidemiologic and clinical relevance in order to evaluate progress and developments in the diagnostic and therapeutic pathways of MDD in Italian and other countries.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Co-dependency in mothers of addicted persons: Data from Bulgaria

2016 ◽  
Vol 33 (S1) ◽  
pp. S623-S623
Author(s):  
D. Ivanova ◽  
V. Giannouli
Keyword(s):  
State Anxiety ◽  
Depression Scale ◽  
Poor Mental Health ◽  
Anxiety And Depression ◽  
Future Research ◽  
High School Degree ◽  
Helping Relationship ◽  
Competing Interest ◽  
High Level ◽  
University Degree

IntroductionCo-dependent relationships are characterized as a type of dysfunctional helping relationship in which there is an excessive reliance on other people for approval and identity. This is very common for female relatives who support/enable another person's addiction, poor mental health, immaturity, and/or irresponsibility.ObjectiveThe aim of the present study is to reveal the co-dependence profile of mothers of addicted persons in Bulgaria.MethodFour hundred Bulgarian women coming from Blagoevgrad, Sofia and Stara Zagora (Mage = 53.55, SDage = 5.58; level of education: 71% with high school degree, 29%with university degree; all mothers of addicted persons) were examined at the Municipal Council on Drug Addiction Blagoevgrad with the STAI-state questionnaire, the ZUNG Self Rating Depression Scale and the Questionnaire of Establishment of Codependency.ResultsResults indicated that in a scale of scores ranging from 2 = minimum to 4 = maximum of co-dependence, this group of women had high self-reported levels of co-dependence (M = 3.6375, SD = .52610), a high depressive profile (M = 49.07, SD = 3.23, and high state anxiety (M = 66.60, SD = 5.58).ConclusionsThe present research suggests that mothers of dependent individuals in Bulgaria show a high level of co-dependency, anxiety and depression. Future research should clarify the reasons of this overall negative emotional profile.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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